Zobrazeno 1 - 10
of 106
pro vyhledávání: '"SATORU SUGIMOTO"'
Autor:
Hiroshi Nittono, Mitsuyoshi Suzuki, Hiromi Suzuki, Satoru Sugimoto, Jun Mori, Rieko Sakamoto, Yugo Takaki, Hisamitsu Hayashi, Hajime Takei, Akihiko Kimura
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Inborn errors of bile acid metabolism (IEBAM) cause cholestasis during the neonatal period, and 8 types of IEBAM have been reported to date. IEBAM accounts for approximately 2% of cases of cholestasis of unknown cause. As only 10 patients have been i
Externí odkaz:
https://doaj.org/article/042438bd43724392be42c9a47166f6fd
Autor:
Yoichi Muramoto, Naoya Murakami, Tatsuki Karino, Satoru Sugimoto, Jun Takatsu, Masaki Oshima, Yasuo Kosugi, Terufumi Kawamoto, Takashi Hirayama, Kazunari Fujino, Yasuhisa Terao, Naoto Shikama
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 42, Iss , Pp 100659- (2023)
We first used MucoUp®, a hyaluronic acid used in endoscopic resection, as a spacer in brachytherapy. In five cervical cancer patients, MucoUp® insertion increased a 90% dose of the high-risk CTV to over 80 Gy while decreasing the dose of organs at
Externí odkaz:
https://doaj.org/article/34dbbd28527e446491529a2cd054b25d
Autor:
Farnaz Shamsi, Ruidan Xue, Tian Lian Huang, Morten Lundh, Yang Liu, Luiz O. Leiria, Matthew D. Lynes, Elena Kempf, Chih-Hao Wang, Satoru Sugimoto, Pasquale Nigro, Kathrin Landgraf, Tim Schulz, Yiming Li, Brice Emanuelli, Srinivas Kothakota, Lewis T. Williams, Niels Jessen, Steen Bønløkke Pedersen, Yvonne Böttcher, Matthias Blüher, Antje Körner, Laurie J. Goodyear, Moosa Mohammadi, C. Ronald Kahn, Yu-Hua Tseng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue. Here the authors show that FGF6 and FGF9 induce UCP1 expression in adipocytes and preadipocytes, via modulation of a transcriptional network that is disso
Externí odkaz:
https://doaj.org/article/de377e337a5a402280aaea762fc97cbe
Autor:
Takeshi Ota, Jun Mori, Yasuhiro Kawabe, Hidechika Morimoto, Shota Fukuhara, Kazuki Kodo, Satoru Sugimoto, Kitaro Kosaka, Hisakazu Nakajima, Hajime Hosoi
Publikováno v:
Children, Vol 9, Iss 10, p 1421 (2022)
Genetic factors play critical roles in the onset and progression of obesity. Brown adipose tissue (BAT) activity is also critical for adiposity. The objective of this study was to evaluate the prevalence and effects of BAT gene polymorphisms in pedia
Externí odkaz:
https://doaj.org/article/b7b700ccb5ec4fbea2105c8c90c4ff0b
Autor:
Shota Fukuhara, Hisakazu Nakajima, Satoru Sugimoto, Kazuki Kodo, Keiichi Shigehara, Hidechika Morimoto, Yusuke Tsuma, Masaharu Moroto, Jun Mori, Kitaro Kosaka, Masafumi Morimoto, Hajime Hosoi
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210184 (2019)
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutation of the methyl-CpG-binding protein 2 (MECP2) gene. Although RTT has been associated with obesity, the underlying mechanism has not yet been elucidated. In this study, fe
Externí odkaz:
https://doaj.org/article/93c43a2564d1446480f57e9f4c56f8aa
Autor:
Kazuki Kodo, Satoru Sugimoto, Hisakazu Nakajima, Jun Mori, Ikuyo Itoh, Shota Fukuhara, Keiichi Shigehara, Taichiro Nishikawa, Kitaro Kosaka, Hajime Hosoi
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173661 (2017)
Erythropoietin (EPO), clinically used as a hematopoietic drug, has received much attention due to its nonhematopoietic effects. EPO reportedly has beneficial effects on obesity and diabetes mellitus. We investigated whether interscapular brown adipos
Externí odkaz:
https://doaj.org/article/e0684de7e0fe47e9807a3ba831586cf7
Publikováno v:
Physica Medica. 100:105-111
We investigated the localization accuracy of the off-isocenter targets using SyncTraX FX4, a new image registration device.In a phantom study, we used a MultiMet-WL Cube with metal targets at different distances from the isocenter. Image registration
Autor:
Satoru Sugimoto, Hebe Agustina Mena, Brian E. Sansbury, Shio Kobayashi, Tadataka Tsuji, Chih-Hao Wang, Xuanzhi Yin, Tian Lian Huang, Joji Kusuyama, Sean D. Kodani, Justin Darcy, Gerson Profeta, Nayara Pereira, Rudolph E. Tanzi, Can Zhang, Thomas Serwold, Efi Kokkotou, Laurie J. Goodyear, Aaron M. Cypess, Luiz Osório Leiria, Matthew Spite, Yu-Hua Tseng
Publikováno v:
Nature Metabolism. 4:775-790
Obesity induces chronic inflammation resulting in insulin resistance and metabolic disorders. Cold exposure can improve insulin sensitivity in humans and rodents, but the mechanisms have not been fully elucidated. Here, we find that cold resolves obe
Autor:
Ryosuke Shirata, Tatsuya Inoue, Satoru Sugimoto, Anneyuko I Saito, Motoko Omura, Yumiko Minagawa, Keisuke Sasai
Publikováno v:
BJR|Open. 5
Objective: Intensity-modulated radiotherapy (IMRT) is a well-established radiotherapy technique for delivering radiation to cancer with high conformity while sparing the surrounding normal tissue. Two main purposes of this study are: (1) to investiga
Autor:
TORU KAWABATA, SATORU SUGIMOTO, CHIE KUROKAWA, KEISUKE USUI, TATSUYA INOUE, HIRONORI NAGATA, HIROYUKI WATANABE, KEISUKE SASAI
Publikováno v:
Juntendo Medical Journal. 68:590-598