Mechanism of degrader-targeted protein ubiquitinability.

Autor: Crowe C; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, UK.; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, James Black Centre, Dow Street, Dundee DD1 5EH, UK., Nakasone MA; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, UK.; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, James Black Centre, Dow Street, Dundee DD1 5EH, UK., Chandler S; Division of Molecular, Cellular and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Craigon C; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, UK., Sathe G; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, UK., Tatham MH; Division of Molecular, Cellular and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Makukhin N; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, James Black Centre, Dow Street, Dundee DD1 5EH, UK., Hay RT; Division of Molecular, Cellular and Developmental Biology, School of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK., Ciulli A; Centre for Targeted Protein Degradation, School of Life Sciences, University of Dundee, 1 James Lindsay Place, Dundee DD1 5JJ, UK.; Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, James Black Centre, Dow Street, Dundee DD1 5EH, UK.

Publikováno v: Science advances [Sci Adv] 2024 Oct 11; Vol. 10 (41), pp. eado6492. Date of Electronic Publication: 2024 Oct 11.

Targeted dephosphorylation of TFEB promotes its nuclear translocation.

Autor: Zhao JF; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Shpiro N; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Sathe G; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Brewer A; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Macartney TJ; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Wood NT; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Negoita F; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark., Sakamoto K; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen, Denmark., Sapkota GP; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.

Publikováno v: IScience [iScience] 2024 Jun 29; Vol. 27 (8), pp. 110432. Date of Electronic Publication: 2024 Jun 29 (Print Publication: 2024).

An In-depth Proteomic Map of Leishmania donovani Isolate from Post Kala-azar Dermal Leishmaniasis (PKDL) Patient.

Autor: Routaray CB; Department of Zoology, Centre for Advanced Study, Savitribai Phule Pune University, Pune, 411007, India., Kumar A; INNODx Solutions Pvt Ltd, Biotech Bioincubator (BBB), Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, 1221001, India., Sundar S; Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India., Sathe G; Institute of Bioinformatics, International Technology Park, Bangalore, 560066, India. gajanan@ibioinformatics.org.; Manipal Academy of Higher Education, Manipal, India. gajanan@ibioinformatics.org., Pawar H; Faculty of Biology, Technion-Israel Institute of Technology, 3200003, Haifa, Israel. harshpawar@campus.technion.ac.il.; Division of Biomedical & Life Sciences, Faculty of Health & Medicine, Lancaster University, Lancaster, UK. harshpawar@campus.technion.ac.il., Pai K; Department of Zoology, Centre for Advanced Study, Savitribai Phule Pune University, Pune, 411007, India. drkalpanapai@gmail.com.

Publikováno v: Acta parasitologica [Acta Parasitol] 2022 Jun; Vol. 67 (2), pp. 687-696. Date of Electronic Publication: 2022 Jan 12.

Neuroanatomical zones of human traumatic brain injury reveal significant differences in protein profile and protein oxidation: Implications for secondary injury events.

Autor: Gowthami N; Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Pursotham N; Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Dey G; Proteomics and Bioinformatics Laboratory, Neurobiology Research Center, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.; Institute of Bioinformatics, Bengaluru, India., Ghose V; Proteomics and Bioinformatics Laboratory, Neurobiology Research Center, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.; Institute of Bioinformatics, Bengaluru, India., Sathe G; Proteomics and Bioinformatics Laboratory, Neurobiology Research Center, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.; Institute of Bioinformatics, Bengaluru, India., Pruthi N; Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Shukla D; Department of Neurosurgery, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Gayathri N; Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Santhoshkumar R; Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Padmanabhan B; Department of Biophysics, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Chandramohan V; Department of Biotechnology, Siddaganga Institute of Technology (SIT), Tumakuru, India., Mahadevan A; Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India., Srinivas Bharath MM; Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.

Publikováno v: Journal of neurochemistry [J Neurochem] 2023 Oct; Vol. 167 (2), pp. 218-247. Date of Electronic Publication: 2023 Sep 11.

Phosphoprotein network analysis of corneal epithelium of keratoconus patients.

Autor: Amit C; Department of Nanobiotechnology, Vision Research Foundation, Sankara Nethralaya Campus, Chennai, India., Ghose V; Institute of Bioinformatics, Bangalore, Karnataka, India., Narayanan J; Department of Nanobiotechnology, Vision Research Foundation, Sankara Nethralaya Campus, Chennai, India., Padmanabhan P; Department of Cornea, Medical Research Foundation Sankara Nethralaya, Chennai, India., Sathe G; Institute of Bioinformatics, Bangalore, Karnataka, India.; Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India., Elchuri S; Department of Nanobiotechnology, Vision Research Foundation, Sankara Nethralaya Campus, Chennai, India.

Publikováno v: Proteomics [Proteomics] 2022 Sep; Vol. 22 (18), pp. e2100416. Date of Electronic Publication: 2022 Jul 13.