Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction

Autor: Robinson, Maximillian A., Kennedy, Alan, Orozco, Carolina T., Chen, Hung-Chang, Waters, Erin, Giovacchini, Dalisay, Yeung, Kay, Filer, Lily, Hinze, Claudia, Lloyd, Christopher, Dovedi, Simon J., Sansom, David M.

Publikováno v: In Cell Reports 24 September 2024 43(9)

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects

Autor: Schwab, Charlotte, Gabrysch, Annemarie, Olbrich, Peter, Patiño, Virginia, Warnatz, Klaus, Wolff, Daniel, Hoshino, Akihiro, Kobayashi, Masao, Imai, Kohsuke, Takagi, Masatoshi, Dybedal, Ingunn, Haddock, Jamanda A., Sansom, David M., Lucena, Jose M., Seidl, Maximilian, Schmitt-Graeff, Annette, Reiser, Veronika, Emmerich, Florian, Frede, Natalie, Bulashevska, Alla, Salzer, Ulrich, Schubert, Desirée, Hayakawa, Seiichi, Okada, Satoshi, Kanariou, Maria, Kucuk, Zeynep Yesim, Chapdelaine, Hugo, Petruzelkova, Lenka, Sumnik, Zdenek, Sediva, Anna, Slatter, Mary, Arkwright, Peter D., Cant, Andrew, Lorenz, Hanns-Martin, Giese, Thomas, Lougaris, Vassilios, Plebani, Alessandro, Price, Christina, Sullivan, Kathleen E., Moutschen, Michel, Litzman, Jiri, Freiberger, Tomas, van de Veerdonk, Frank L., Recher, Mike, Albert, Michael H., Hauck, Fabian, Seneviratne, Suranjith, Pachlopnik Schmid, Jana, Kolios, Antonios, Unglik, Gary, Klemann, Christian, Speckmann, Carsten, Ehl, Stephan, Leichtner, Alan, Blumberg, Richard, Franke, Andre, Snapper, Scott, Zeissig, Sebastian, Cunningham-Rundles, Charlotte, Giulino-Roth, Lisa, Elemento, Olivier, Dückers, Gregor, Niehues, Tim, Fronkova, Eva, Kanderová, Veronika, Platt, Craig D., Chou, Janet, Chatila, Talal A., Geha, Raif, McDermott, Elizabeth, Bunn, Su, Kurzai, Monika, Schulz, Ansgar, Alsina, Laia, Casals, Ferran, Deyà-Martinez, Angela, Hambleton, Sophie, Kanegane, Hirokazu, Taskén, Kjetil, Neth, Olaf, Grimbacher, Bodo

Publikováno v: In The Journal of Allergy and Clinical Immunology December 2018 142(6):1932-1946

Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity

Autor: Hou, Tie Zheng, Olbrich, Peter, Soto, Jose Manuel Lucena, Sanchez, Berta, Moreno, Paula Sanchez, Borte, Stephan, Stauss, Hans J., Burns, Siobhan O., Walker, Lucy S.K., Pan-Hammarström, Qiang, Hammarström, Lennart, Sansom, David M., Neth, Olaf

Publikováno v: In Clinical Immunology March 2018 188:94-102

CTLA-4: a moving target in immunotherapy

Autor: Rowshanravan, Behzad ^*, Halliday, Neil ^*, Sansom, David M.

Publikováno v: In Blood 4 January 2018 131(1):58-67

Thymus transplantation for complete DiGeorge syndrome: European experience

Autor: Davies, E. Graham, Cheung, Melissa, Gilmour, Kimberly, Maimaris, Jesmeen, Curry, Joe, Furmanski, Anna, Sebire, Neil, Halliday, Neil, Mengrelis, Konstantinos, Adams, Stuart, Bernatoniene, Jolanta, Bremner, Ronald, Browning, Michael, Devlin, Blythe, Erichsen, Hans Christian, Gaspar, H. Bobby, Hutchison, Lizzie, Ip, Winnie, Ifversen, Marianne, Leahy, T. Ronan, McCarthy, Elizabeth, Moshous, Despina, Neuling, Kim, Pac, Malgorzata, Papadopol, Alina, Parsley, Kathryn L., Poliani, Luigi, Ricciardelli, Ida, Sansom, David M., Voor, Tiia, Worth, Austen, Crompton, Tessa, Markert, M. Louise, Thrasher, Adrian J.

Publikováno v: In The Journal of Allergy and Clinical Immunology December 2017 140(6):1660-1670