Zobrazeno 1 - 10
of 258
pro vyhledávání: '"SANG YUN HA"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma (HCC) often arises in the cirrhotic livers, highlighting the intricate link between hepatic fibrosis and carcinogenesis. Reactive oxygen species produced by NADPH oxidase 4 (NOX4) contribute to liver injury leading t
Externí odkaz:
https://doaj.org/article/23bf81cb4bac434a9ce96abb1a7a318c
Autor:
Ji Eun Kim, Minjee Kim, Min-Ji Kim, Eun Ran Kim, Sung Noh Hong, Dong Kyung Chang, Sang Yun Ha, Young-Ho Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Limited research has been performed to determine if histologic improvement serves as a prognosticator for endoscopic remission, a key therapeutic target for ulcerative colitis (UC). The primary aim of the study was to evaluate if histologica
Externí odkaz:
https://doaj.org/article/07c59cee6d3e44729125d6e3d42d3b48
Autor:
Sangbin Han, Ji Hye Kwon, Kyo Won Lee, Sanghoon Lee, Gyu Sung Choi, Jong Man Kim, Justin Sangwook Ko, Mi Sook Gwak, Gaab Soo Kim, Sang Yun Ha, Jae-Won Joh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Greater graft-failure-risk of female-to-male liver transplantation (LT) is thought to be due to acute decrease in hepatic-estrogen-signaling. Our previous research found evidence that female hepatic-estrogen-signaling decreases after 40 year
Externí odkaz:
https://doaj.org/article/e97e4320938f4a69988ab730fb100529
Autor:
So Young Kang, Deok Geun Kim, Hyunjin Kim, Yoon Ah Cho, Sang Yun Ha, Ghee Young Kwon, Kee-Taek Jang, Kyoung-Mee Kim
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-10 (2022)
Abstract Background Mutations in the telomerase reverse transcriptase (TERT) promoter region have been proposed as novel mechanisms for the transcriptional activation of telomerase. Two recurrent mutations in the TERT promoter, C228T and C250T, are p
Externí odkaz:
https://doaj.org/article/6732b5db0fa54118b8e97dd30cc5be89
Autor:
Jung Yong Hong, Hee Jin Cho, Jason K. Sa, Xiaoqiao Liu, Sang Yun Ha, Taehyang Lee, Hajung Kim, Wonseok Kang, Dong Hyun Sinn, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Hee Chul Park, Tae Wook Kang, Hyunchul Rhim, Su Jin Lee, Razvan Cristescu, Jeeyun Lee, Yong Han Paik, Ho Yeong Lim
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background A limited number of studies have characterized genomic properties of hepatocellular carcinoma (HCC) patients in response to anti-PD-1 immunotherapy. Methods Herein, we performed comprehensive molecular characterization of immediat
Externí odkaz:
https://doaj.org/article/9436a920f67a4275b778a98aec3608cb
Autor:
Dong Ik Cha, Tae Wook Kang, Ji Hye Min, Ijin Joo, Dong Hyun Sinn, Sang Yun Ha, Kyunga Kim, Gunwoo Lee, Jonghyon Yi
Publikováno v:
Ultrasonography, Vol 40, Iss 4, Pp 565-574 (2021)
Purpose The aim of this study was to develop and validate a fully-automatic quantification of the hepatorenal index (HRI) calculated by a deep convolutional neural network (DCNN) comparable to the interpretations of radiologists experienced in ultras
Externí odkaz:
https://doaj.org/article/de59266c5a5c4b958d1513baaace0d4f
Deep learning-based virtual cytokeratin staining of gastric carcinomas to measure tumor–stroma ratio
Autor:
Yiyu Hong, You Jeong Heo, Binnari Kim, Donghwan Lee, Soomin Ahn, Sang Yun Ha, Insuk Sohn, Kyoung-Mee Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The tumor–stroma ratio (TSR) determined by pathologists is subject to intra- and inter-observer variability. We aimed to develop a computational quantification method of TSR using deep learning-based virtual cytokeratin staining algorithms
Externí odkaz:
https://doaj.org/article/665a23e325834b819fadac98a5eb0531
Autor:
Hongsik Kim, Ryul Kim, Hyunji Jo, Hye Ryeon Kim, Joohyun Hong, Sang Yun Ha, Joon Oh Park, Seung Tae Kim
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 15 (2022)
Background: Expression of programmed death-ligand 1 (PD-L1) has been reported to correlate with response to immune checkpoint inhibitors (ICIs) in various tumor types. However, there are few data on the role of PD-L1 expression as a predictive and pr
Externí odkaz:
https://doaj.org/article/919143fb97924cfb80ed8df532815d79
Autor:
Dong Ik Cha, Min Woo Lee, Woo Kyoung Jeong, Sang Yun Ha, Soo Hyun Ahn, Hyunchul Rhim, Hyo Keun Lim
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 332-340 (2021)
Objective To evaluate the performance of dual internally cooled wet tip (ICWT) radiofrequency electrodes in comparison to dual internally cooled tip (ICT) electrodes. Methods Twenty ablation zones were created for each type of electrodes. Planned pro
Externí odkaz:
https://doaj.org/article/bd299787869f49da86d316cdc9aa4637
Autor:
Hongsik Kim, Ryul Kim, Hye Ryeon Kim, Hyunji Jo, Hana Kim, Sang Yun Ha, Joon Oh Park, Young Suk Park, Seung Tae Kim
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
HER2 aberrations have been reported as a novel biomarker in HER2-directed therapy or as a prognostic marker in various tumor types. However, in advanced biliary tract cancer (BTC), there have been few studies regarding HER2 aberrations as a biomarker
Externí odkaz:
https://doaj.org/article/5e4b89c2f10e47c5b4f8a0fe7c49f9d7