Zobrazeno 1 - 10
of 240
pro vyhledávání: '"SANG RYONG KIM"'
Autor:
Sehwan Kim, Chanchal Sharma, Jungwan Hong, Jong-Heon Kim, Youngpyo Nam, Min Sung Kim, Tae Yong Lee, Kyung-Suk Kim, Kyoungho Suk, Ho-Won Lee, Sang Ryong Kim
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Defects in the ataxin-2 (ATXN-2) protein and CAG trinucleotide repeat expansion in its coding gene, Atxn-2, cause the neurodegenerative disorder spinocerebellar ataxia type 2 (SCA2). While clinical studies suggest potential benefi
Externí odkaz:
https://doaj.org/article/e3e724309f424a239fa4f88000060773
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2507 (2024)
Spinocerebellar ataxia (SCA) is a heterogeneous disorder characterized by impaired balance and coordination caused by cerebellar dysfunction. The absence of treatments approved by the U.S. Food and Drug Administration for SCA has driven the investiga
Externí odkaz:
https://doaj.org/article/110caf4066ed439c80101e95786f0675
Autor:
Eunju Leem, Sehwan Kim, Chanchal Sharma, Youngpyo Nam, Tae Yeon Kim, Minsang Shin, Seok-Geun Lee, Jaekwang Kim, Sang Ryong Kim
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 380 (2024)
Although granule cell dispersion (GCD) in the hippocampus is known to be an important feature associated with epileptic seizures in temporal lobe epilepsy (TLE), the endogenous molecules that regulate GCD are largely unknown. In the present study, we
Externí odkaz:
https://doaj.org/article/1c22e324f30c4b8eab3bf3aafb1308d3
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 28, Iss , Pp 100593- (2023)
We recently demonstrated that prothrombin kringle-2 (pKr-2) derived from blood-brain barrier (BBB) disruption could induce hippocampal neurodegeneration and object recognition impairment through neurotoxic inflammatory responses in the five familial
Externí odkaz:
https://doaj.org/article/d4e15b25c4d34d0dbdeb4f414d216f50
Autor:
Chanchal Sharma, Sang Ryong Kim
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 9, Pp 1948-1949 (2023)
Externí odkaz:
https://doaj.org/article/4113693f08054b5e88e5c2e18340d865
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1383 (2023)
The blood–brain barrier (BBB) restricts entry of neurotoxic plasma components, blood cells, and pathogens into the brain, leading to proper neuronal functioning. BBB impairment leads to blood-borne protein infiltration such as prothrombin, thrombin
Externí odkaz:
https://doaj.org/article/ddfb494a57fc45e1a14157b887e5ccd3
Autor:
Shinrye Lee, Seyeon Kim, Ha-Young Kang, Hye Ryeong Lim, Younghwi Kwon, Myungjin Jo, Yu-Mi Jeon, Sang Ryong Kim, Kiyoung Kim, Chang Man Ha, Seongsoo Lee, Hyung-Jun Kim
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-22 (2020)
Abstract Background Cytoplasmic inclusions of transactive response DNA binding protein of 43 kDa (TDP-43) in neurons and astrocytes are a feature of some neurodegenerative diseases, such as frontotemporal lobar degeneration with TDP-43 (FTLD-TDP) and
Externí odkaz:
https://doaj.org/article/c7b701015c05417c8041f989cf386104
Autor:
Jae Man Lee, Sang Ryong Kim
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2675-2676 (2022)
Externí odkaz:
https://doaj.org/article/4aea8e1cf7e74f879d29a3f6011e7ffd
Autor:
Shinrye Lee, Younghwi Kwon, Seyeon Kim, Myungjin Jo, Yu-Mi Jeon, Mookyung Cheon, Seongsoo Lee, Sang Ryong Kim, Kiyoung Kim, Hyung-Jun Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Transactive response DNA-binding protein 43 (TDP-43)-induced neurotoxicity is currently well recognized as a contributor to the pathology of amyotrophic lateral sclerosis (ALS), and the deposition of TDP-43 has been linked to other neurodegenerative
Externí odkaz:
https://doaj.org/article/7fb100decca949a7bea5b2ea20b8929b
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 742 (2022)
The blood–brain barrier (BBB) plays a vital role in maintaining the specialized microenvironment of the brain tissue. It facilitates communication while separating the peripheral circulation system from the brain parenchyma. However, normal aging a
Externí odkaz:
https://doaj.org/article/d65df15c74694478b2f4ecd12aeb73c3