Zobrazeno 1 - 10
of 45
pro vyhledávání: '"SANDRO PERCARIO"'
Autor:
Ângelo Antônio Barbosa de Moraes, Celeste de Jesus Pereira Franco, Oberdan Oliveira Ferreira, Everton Luiz Pompeu Varela, Lidiane Diniz do Nascimento, Márcia Moraes Cascaes, Dehon Ricardo Pereira da Silva, Sandro Percário, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Publikováno v:
Molecules, Vol 27, Iss 17, p 5460 (2022)
The Myrtaceae family is one of the most representative in the Amazon. Several species have high added-value pharmacological potential. In order to contribute to the knowledge of the aromatic profile of Myrtaceae species from the Amazon, the present s
Externí odkaz:
https://doaj.org/article/ee5591d4517d45aa9d77e32c3bf0e65a
Autor:
João Victor da Silva e Silva, Helliton Patrick Cordovil Brigido, Kelly Cristina Oliveira de Albuquerque, Josiwander Miranda Carvalho, Jordano Ferreira Reis, Lara Vinhal Faria, Márlia Regina Coelho-Ferreira, Fernando Tobias Silveira, Agnaldo da Silva Carneiro, Sandro Percário, Andrey Moacir do Rosário Marinho, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 24, Iss 4, p 785 (2019)
Chemotherapy is limited in the treatment of leishmaniasis due to the toxic effects of drugs, low efficacy of alternative treatments, and resistance of the parasite. This work assesses the in vitro activity of flavopereirine on promastigote cultures o
Externí odkaz:
https://doaj.org/article/cb62eb519a2c44d1b9b134e1ca1eec67
Autor:
Antônio Rafael Quadros Gomes, Ana Laura Gadelha Castro, Gleison Gonçalves Ferreira, Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Valdicley Vieira Vale, Liliane Almeida Carneiro, Maria Fâni Dolabela, Sandro Percario
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
In vitro studies with Plasmodium falciparum have demonstrated the antiparasitic activity of E. plicata, attributed to its naphthoquinones. This study reports on pro-inflammatory changes in mice infected with P. berghei and correlates these changes wi
Externí odkaz:
https://doaj.org/article/449d64e562a549b285b7ea511d854186
Autor:
EVERTON LUIZ P. VARELA, ANTÔNIO RAFAEL Q. GOMES, ALINE S.B. DOS SANTOS, JORDDY N. DA CRUZ, ELIETE P. DE CARVALHO, BENEDITO ANTÔNIO P. DOS PRAZERES, MARIA FANI DOLABELA, SANDRO PERCARIO
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 3 (2024)
Abstract Oxidative stress is involved in the pathogenesis of malaria, causing anemia, respiratory complications, and cerebral malaria. To mitigate oxidative stress, we investigated the effect of nutritional supplementation whit lycopene (LYC) on the
Externí odkaz:
https://doaj.org/article/9521e30f3542454fae72e8acc3701f99
Autor:
Kelly Cristina Oliveira de Albuquerque, Andreza do Socorro Silva da Veiga, Fernando Tobias Silveira, Marliane Batista Campos, Ana Paula Lima da Costa, Ananda Karolyne Martins Brito, Paulo Ricardo de Souza Melo, Sandro Percario, Fábio Alberto de Molfetta, Maria Fâni Dolabela
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Introduction: Leishmaniasis is caused by protozoa of the genus Leishmania, classified as tegumentary and visceral. The disease treatment is still a serious problem, due to the toxic effects of available drugs, the costly treatment and reports of para
Externí odkaz:
https://doaj.org/article/322bc5febfe34e7e8011bcef5e2c058f
Autor:
Rufine Azonsivo, Kelly Cristina Oliveira de Albuquerque, Ana Laura Gadelha Castro, Juliana Correa-Barbosa, Helena Joseane Raiol de Souza, Andryo Orfi de Almada-Vilhena, Gleison Gonçalves Ferreira, Anderson Albuquerque de Souza, Andrey Moacir do Rosario Marinho, Sandro Percario, Cleusa Yoshiko Nagamachi, Julio Cesar Pieczarka, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 28, Iss 14, p 5336 (2023)
The alkaloids isolated from Zanthoxylum rhoifolium have demonstrated great pharmacological potential; however, the toxic profiles of these extracts and fractions are still not well elucidated. This study evaluated the toxicity of the ethanol extract
Externí odkaz:
https://doaj.org/article/1549686c0fd24f3d8c51faf9f205d5ef
Autor:
Antônio Rafael Quadros Gomes, Jorddy Neves Cruz, Ana Laura Gadelha Castro, Heliton Patrick Cordovil Brigido, Everton Luiz Pompeu Varela, Valdicley Vieira Vale, Liliane Almeida Carneiro, Gleison Gonçalves Ferreira, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 28, Iss 14, p 5557 (2023)
From Eleutherine plicata, naphthoquinones, isoeleutherine, and eleutherol were isolated, and previous studies have reported the antioxidant activity of these metabolites. The present work evaluated the role of oxidative changes in mice infected with
Externí odkaz:
https://doaj.org/article/f5df926b26904defa91e180bebd66971
Autor:
Antonio Rafael Quadros Gomes, Natasha Costa da Rocha Galucio, Kelly Cristina Oliveira de Albuquerque, Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Ana Laura Gadelha Castro, Valdicley Vieira Vale, Marcelo Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfeta, Liliane Almeida Carneiro, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1480-1487 (2021)
Eleutherine plicata has been shown to be a promising medicinal plant, and its activity has been associated with naphthoquinones. The present study aimed at evaluating the cytotoxicity, genotoxicity, and oral toxicity of the ethanol extract (EEEp), di
Externí odkaz:
https://doaj.org/article/b9b57379b9ae405281cf9a6653e7f86f
Autor:
Kelly Cristina Oliveira de Albuquerque, Natasha Costa da Rocha Galucio, Gleison Gonçalves Ferreira, Ana Carolina Sousa Quaresma, Valdicley Vieira Vale, Marcelo de Oliveira Bahia, Rommel Mario Rodriguez Burbano, Fábio Alberto de Molfetta, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 28, Iss 4, p 1630 (2023)
This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular doc
Externí odkaz:
https://doaj.org/article/fed33be150bb468c810d7b40a972710d
Autor:
Gleison Gonçalves Ferreira, Ana Carolina Sousa Quaresma, Dayse Lúcia do Nascimento Brandão, Andrey Moacir do Rosario Marinho, José Edson de Sousa Siqueira, Kamila Leal Correa, José Otávio Carréra Silva-Júnior, Sandro Percario, Maria Fâni Dolabela
Publikováno v:
Molecules, Vol 28, Iss 1, p 231 (2022)
Cancer is a multifactorial organic dysfunction for which great efforts are being devoted in searching for new treatments and therapeutic adjuvants. Annona muricata is a fruit that has promising activity against several types of cancer, as it contains
Externí odkaz:
https://doaj.org/article/c6ad231157404ecf8d39f3d21a0d75db