Zobrazeno 1 - 10
of 68
pro vyhledávání: '"SANDRA MEGANTARA"'
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 6, Pp 1079-1089 (2024)
Context: Simvastatin can be modified by the formation of multicomponent crystals to increase its solubility. Aims: To compare the solubility of multicomponent simvastatin crystals to pure simvastatin. Methods: The in silico study of simvastatin
Externí odkaz:
https://doaj.org/article/99c2a2b386f34cbba2670a6e497be27d
Publikováno v:
Journal of HerbMed Pharmacology, Vol 13, Iss 3, Pp 491-500 (2024)
Introduction: Costus cuspidatus and Costus subsessilis have shown cytotoxic effects in HL60, Jurkat, and THP-1 cells. This study aimed to evaluate the cytotoxicity and apoptotic activity of the ethanol extract and fractions of C. speciosus leaves aga
Externí odkaz:
https://doaj.org/article/dec676226c584ef585679c4eca74fa6a
Publikováno v:
Pharmacia, Vol 70, Iss 4, Pp 1479-1486 (2023)
A Carvedilol is a member of BCS class II, it has a low solubility and bioavailability. This work intends to increase the solubility of carvedilol using a multicomponent crystal method. Based on in silico investigations showed that carvedilol-arginine
Externí odkaz:
https://doaj.org/article/b38c6ca1fc46469da31d9e32926e51ce
Publikováno v:
Pharmacia, Vol 70, Iss 2, Pp 283-290 (2023)
Multicomponent crystallization is a method that can modify the physicochemical properties of Carvedilol (CVD), thereby increasing its solubility. Based on in silico screening the coformers (Benzoic Acid, Isonicotinamide, and Saccharin) showed non-cov
Externí odkaz:
https://doaj.org/article/c1862af2c86342068fda984761de6818
Autor:
Hanggara Arifian, Rani Maharani, Sandra Megantara, Nur Kusaira Khairul Ikram, Muchtaridi Muchtaridi
Publikováno v:
Applied Sciences, Vol 14, Iss 13, p 5549 (2024)
Natural compounds have demonstrated good biological activity when combined with certain amino acids. For example, a glycine-conjugated glycyrrhetinic acid exhibits heightened efficiency against MCF7 cancer cells. Consequently, a molecular modeling an
Externí odkaz:
https://doaj.org/article/ce69ad63468144c78de14494c4e46524
Publikováno v:
Molecules, Vol 29, Iss 13, p 2983 (2024)
Statins are cholesterol-lowering drugs with a mechanism of inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase, but long-term use can cause side effects. An example of a plant capable of reducing cholesterol levels is Angelica keiskei (ashitaba). The
Externí odkaz:
https://doaj.org/article/23303c7a4909496297d80af65aba17f7
Publikováno v:
Molecules, Vol 29, Iss 7, p 1680 (2024)
Metals are beneficial to life, but the presence of these elements in excessive amounts can harm both organisms and the environment; therefore, detecting the presence of metals is essential. Currently, metal detection methods employ powerful instrumen
Externí odkaz:
https://doaj.org/article/95af2e77206a41c78f30bf6c83103a3a
Publikováno v:
Indonesian Journal of Chemistry, Vol 23, Iss 2, Pp 349-357 (2023)
Carvedilol (CVD) is a non-selective β-blocker. CVD is included in BCS class II. It has low water solubility. In this research, solid dispersion was used to increase the solubility and dissolution profile of CVD. In silico study using the ligand-liga
Externí odkaz:
https://doaj.org/article/987f515a3abd4586bf48900fa10f7456
Publikováno v:
Cosmetics, Vol 11, Iss 1, p 21 (2024)
Kojic acid (KA) has emerged as a prominent tyrosinase inhibitor with considerable potential in cosmetic applications; however, its susceptibility to instability during storage poses a challenge to its widespread use. This review explores the advancem
Externí odkaz:
https://doaj.org/article/c5f0d463a8d14be6a503ec55fd45098c
Autor:
Mutakin, Nyi Mekar Saptarini, Riezki Amalia, Sri Adi Sumiwi, Sandra Megantara, Febrina Amelia Saputri, Jutti Levita
Publikováno v:
Cosmetics, Vol 10, Iss 6, p 149 (2023)
In Indonesia, plants have been indigenously used to treat various diseases and as cosmetics. It is always challenging to explore the molecular interactions of phenolic compounds towards the levels of constituents that contribute to the biological act
Externí odkaz:
https://doaj.org/article/e513b5033d96425ba54f30b2f495e67c