Výsledky vyhledávání - "SAMIR MOHAMED AWAD"

Akademický článek

Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors

Autor: Sahar A. Ali, Samir Mohamed Awad, Ahmed Mohammed Said, Shahenda Mahgoub, Heba Taha, Naglaa Mohamed Ahmed

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 847-863 (2020)

Oxidative stress is one of the main causes of significant severe diseases. The discovery of new potent antioxidants with high efficiency and low toxicity is a great demand in the field of medicinal chemistry. Herein, we report the design, synthesis m

Externí odkaz: https://doaj.org/article/77ea4f1e407d4572a3f773abe54807fd

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Akademický článek

Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents

Autor: Samir Mohamed Awad, Shima Mahmoud Ali, Yara Essam Mansour, Samar Said Fatahala

Publikováno v: Molecules, Vol 26, Iss 10, p 2988 (2021)

Since herpes simplex virus type 1 (HSV-1) infection is so widespread, several antiviral drugs have been developed to treat it, among which are uracil nucleosides. However, there are major problems with the current medications such as severe side-effe

Externí odkaz: https://doaj.org/article/adc6e2d43d4d45e4875b73bce918bb1b

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Design, synthesis, ADME, biological evaluation and molecular dynamic studies of natural and synthetic remedy of Herpes simplex virus type-1

Autor: Suhad Sami, Humadi, Samir Mohamed, Awad, Ahmed Abd, Elkader El-Rashedy, Mohamed Fathy, El-Shehry

Publikováno v: Pakistan journal of pharmaceutical sciences. 35(4(Special))

Garlic (known as; Allium sativum) is one of the most widely used medicinal plants in the world. Allicin is the major agent of garlic that gives its known pharmacological activities as anti-inflammatory, antibacterial, antifungal, antiviral and antiox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65327ce1ba4689bd1235c46f2a193662
https://pubmed.ncbi.nlm.nih.gov/36218096

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Synthesis and antimicrobial evaluation of some 6-aryl-5-cyano-2-thiouracil derivatives

Autor: MOSAAD SAYED MOHAMED, SAMIR MOHAMED AWAD, NAGLAA MOHAMED Ahmed

Publikováno v: Acta Pharmaceutica
Volume 61
Issue 2

A series of 6-aryl-5-cyano-2-thiouracil derivatives (1a-d) was synthesized by the reaction of ethyl cyanoacetate with thiourea and aldehydes. These products were used as intermediate compounds for the synthesis of a number of thiouracil derivatives (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______951::b3ce372dbd97f0ca7c06ffeb058709e7
https://hrcak.srce.hr/66190

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