Zobrazeno 1 - 10
of 594
pro vyhledávání: '"SAM68"'
Autor:
Sehoon Hong, Kyurae Kim, Young-Ri Shim, Jiyeon Park, Sung Eun Choi, Hyungyu Min, Seulgi Lee, Ji-Joon Song, Suk-Jo Kang, Won-Il Jeong, Rho Hyun Seong, Seyun Kim
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Phospholipase C gamma 1 (PLCγ1) is an important mediator of the T cell receptor (TCR) and growth factor signaling. PLCγ1 is activated by Src family kinases (SFKs) and produces inositol 1,4,5-triphosphate (InsP3) from phosphatidy
Externí odkaz:
https://doaj.org/article/29ed39e31ccc47c68fe3da67de62d33d
Autor:
Zeshen Wu, Yulu Peng, Longbin Xiong, Jun Wang, Zhen Li, Kang Ning, Minhua Deng, Ning Wang, Wensu Wei, Zhiyong Li, Pei Dong, Chunping Yu, Fangjian Zhou, Zhiling Zhang
Publikováno v:
Cancer Medicine, Vol 11, Iss 19, Pp 3674-3686 (2022)
Abstract Sunitinib is one of the first‐line targeted drugs for metastatic renal cell carcinoma (RCC) with dual effects of antiangiogensis and proapoptosis. Sam68 (Src‐associated in mitosis, 68 KDa), is found being involved in cell apoptosis. This
Externí odkaz:
https://doaj.org/article/c2a28f99e24840dca26deb11cf889c05
Akademický článek
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Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 473-487 (2021)
Mounting evidence reveals that dysregulation of circular RNAs (circRNAs) is involved in the development of glioblastoma. Leucine-rich repeat-containing 4 (LRRC4) has been shown to suppress tumors in glioblastoma. However, whether LRRC4 can regulate t
Externí odkaz:
https://doaj.org/article/1ce7fa5cd8954ffda577243f7151b819
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Xingjia Lu, Jian Zhong, Linlin Liu, Wenzhu Zhang, Shengdi Zhao, Liang Chen, Yuxian Wei, Hong Zhang, Jingxuan Wu, Wenlin Chen, Fei Ge
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer is the most common female malignancy, but the mechanisms regulating gene expression leading to its development are complex. In recent years, as epigenetic research has intensified, RNA-binding proteins (RBPs) have been identified as a c
Externí odkaz:
https://doaj.org/article/74e0827832134e1a86081353878805e1
Autor:
Chiara Naro, Federica Barbagallo, Cinzia Caggiano, Monica De Musso, Valentina Panzeri, Silvia Di Agostino, Maria Paola Paronetto, Claudio Sette
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer subtype. Poor prognosis in TNBC is partly due to lack of efficacious targeted therapy and high propensity to metastasize. Dysregulation of alternative splicing has rece
Externí odkaz:
https://doaj.org/article/8fd102bbf5064ca7ba9da7c9767fb0ff
Autor:
Teresa Vilariño-García, Antonio Pérez-Pérez, Esther Santamaría-López, Nicolás Prados, Manuel Fernández-Sánchez, Víctor Sánchez-Margalet
Publikováno v:
Endocrine Connections, Vol 9, Iss 6, Pp 479-488 (2020)
Introduction: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding protein with signaling functi
Externí odkaz:
https://doaj.org/article/c0a796d4ca7845628dade7ad81e7827f
Autor:
Teresa Vilariño-García, Pilar Guadix, Mónica Dorado-Silva, Pascual Sánchez-Martín, Antonio Pérez-Pérez, Víctor Sánchez-Margalet
Publikováno v:
Cells, Vol 11, Iss 18, p 2821 (2022)
Background and objective: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, which leads to subfertility. PCOS is the most frequent metabolic diso
Externí odkaz:
https://doaj.org/article/db6ae8952b274bd485ab6dfc9d9cbe97
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11469 (2022)
Hepatic glucose production (HGP) is an important component of glucose homeostasis, and deregulated HGP, particularly through gluconeogenesis, contributes to hyperglycemia and pathology of type-2 diabetes (T2D). It has been shown that the gluconeogeni
Externí odkaz:
https://doaj.org/article/e020f2e198324e0bbb57bd88f0c1f382