Zobrazeno 1 - 10
of 440
pro vyhledávání: '"SALEM CHOUAIB"'
Autor:
Mohammad A. Iqbal, Shumaila Siddiqui, Kirk Smith, Prithvi Singh, Bhupender Kumar, Salem Chouaib, Sriram Chandrasekaran
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108059- (2023)
Summary: Extensive metabolic heterogeneity in breast cancers has limited the deployment of metabolic therapies. To enable patient stratification, we studied the metabolic landscape in breast cancers (∼3000 patients combined) and identified three su
Externí odkaz:
https://doaj.org/article/5062fb9301bd411584858f4d2002c818
Autor:
Sabina Di Matteo, Enrico Munari, Piera Filomena Fiore, Silvia Santopolo, Camilla Sampaoli, Andrea Pelosi, Salem Chouaib, Nicola Tumino, Paola Vacca, Francesca Romana Mariotti, Stefan Ebert, Markus Machwirth, Dorothee Haas, Marco Pezzullo, Gabriella Pietra, Melania Grottoli, Stephanie Buart, Erwan Mortier, Enrico Maggi, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundMelanoma is a lethal skin cancer, and the risk of developing it is increased by exposure to ultraviolet (UV) radiation. The production of cytokines such as interleukin-15 (IL-15), induced by the exposure of skin cells to UV rays, could also
Externí odkaz:
https://doaj.org/article/019fa5592eae43aba1002be803c63084
Autor:
Raefa Abou Khouzam, Mohak Sharda, Shyama Prasad Rao, Stephanie Maame Kyerewah-Kersi, Nagwa Ahmed Zeinelabdin, Ayda Shah Mahmood, Husam Nawafleh, Munazza Samar Khan, Goutham Hassan Venkatesh, Salem Chouaib
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Hypoxia afflicts the microenvironment of solid tumors fueling malignancy. We investigated the impact of long hypoxia exposure on transcriptional remodeling, tumor mutational burden (TMB), and genomic instability of cancer cells that were grouped base
Externí odkaz:
https://doaj.org/article/6fed90ce929d4c819d8d8363db37fa79
Autor:
Saravanan Ramesh, Preethi Selvakumar, Mohamed Yazeer Ameer, Sen Lian, Abdulqadir Ismail M. Abdullah Alzarooni, Shreesh Ojha, Anshuman Mishra, Ashutosh Tiwari, Ajeet Kaushik, Young Do Jung, Salem Chouaib, Vinoth-Kumar Lakshmanan
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The development of new therapeutic strategies is on the increase for prostate cancer stem cells, owing to current standardized therapies for prostate cancer, including chemotherapy, androgen deprivation therapy (ADT), radiotherapy, and surgery, often
Externí odkaz:
https://doaj.org/article/e3471f6e5b224238a8c51f9bf7ea002e
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/b543b008b19a4c98bcc11855f9c54b5e
Publikováno v:
Immuno, Vol 1, Iss 3, Pp 160-173 (2021)
Evading the immune system is one of the hallmarks of cancer. Tumors escape anti-tumor immunity through cell-intrinsic means and the assembly of an immunosuppressive tumor microenvironment. By significantly boosting the host immune system, cancer immu
Externí odkaz:
https://doaj.org/article/4ebe87c03b174c12a9867d1f8511f7c5
Autor:
Bassam Janji, Salem Chouaib
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Almost all solid tumors display hypoxic areas in the tumor microenvironment associated with therapeutic failure. It is now well established that the abnormal growth of malignant solid tumors exacerbates their susceptibility to hypoxia. Therefore, tar
Externí odkaz:
https://doaj.org/article/b25b4c3ca625440ca4853a208901f97f
Autor:
Laurence Albiges, Bernard Escudier, Catherine Sautes-Fridman, Benoit Beuselinck, Lydie Cassard, Maxime Meylan, Nathalie Rioux-Leclercq, Aude Desnoyer, Guillaume Lacroix, Nathalie Chaput-Gras, Marie Naigeon, Lisa Boselli, Salem Chouaib, Lucia Carril-Ajuria, Cécile Dalban, Yann Vano, Sylvie Chabaud, Janice Barros-Monteiro, Antoine Bougoüin, Irelka Colina-Moreno, Florence Tantot, Caroline De Oliveira, Wolf Herve Fridman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)
Background The phase II NIVOREN GETUG-AFU 26 study reported safety and efficacy of nivolumab in patients with metastatic clear cell renal cell carcinoma (m-ccRCC) in a ‘real-world setting’. We conducted a translational-research program to determi
Externí odkaz:
https://doaj.org/article/3b8448255849403eaa7f2df395db9ee2
Autor:
Stéphanie Corgnac, Fathia Mami-Chouaib, Isabelle Damei, Gwendoline Gros, Aziza Caidi, Stéphane Terry, Salem Chouaib, Marc Deloger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/b9a28dd064d1416086a83c3d2bbc1a7f
Autor:
Agnete S. T. Engelsen, Maria L. Lotsberg, Raefa Abou Khouzam, Jean-Paul Thiery, James B. Lorens, Salem Chouaib, Stéphane Terry
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development and implementation of Immune Checkpoint Inhibitors (ICI) in clinical oncology have significantly improved the survival of a subset of cancer patients with metastatic disease previously considered uniformly lethal. However, the low res
Externí odkaz:
https://doaj.org/article/2325540166db4535942a5d6fcd305dd0