Zobrazeno 1 - 10
of 30
pro vyhledávání: '"SAKI HIRAKATA"'
Autor:
Saki Hirakata, MD, Hiroki Aoki, MD, PhD, Satoko Ohno-Urabe, MD, PhD, Michihide Nishihara, MD, PhD, Aya Furusho, MD, PhD, Norifumi Nishida, MD, Sohei Ito, MD, Makiko Hayashi, MD, Hideo Yasukawa, MD, PhD, Tsutomu Imaizumi, MD, PhD, Sinichi Hiromatsu, MD, PhD, Hiroyuki Tanaka, MD, PhD, Yoshihiro Fukumoto, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
Summary: Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of
Externí odkaz:
https://doaj.org/article/83a8bf407ee34e8189a3a5b7ac49083d
Autor:
Sohei Ito, Yohei Hashimoto, Ryohei Majima, Eichi Nakao, Hiroki Aoki, Michihide Nishihara, Satoko Ohno-Urabe, Aya Furusho, Saki Hirakata, Norifumi Nishida, Makiko Hayashi, Koichiro Kuwahara, Yoshihiro Fukumoto
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229888 (2020)
Aortic dissection (AD) is a major cause of acute aortic syndrome with high mortality due to the destruction of aortic walls. Although recent studies indicate the critical role of inflammation in the disease mechanism of AD, it is unclear how inflamma
Externí odkaz:
https://doaj.org/article/5fa6f76b2ac84e608e3e7b1cff7720d9
Autor:
Aya Furusho, Hiroki Aoki, Satoko Ohno‐Urabe, Michihide Nishihara, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Tsutomu Imaizumi, Shinichi Hiromatsu, Hidetoshi Akashi, Hiroyuki Tanaka, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 6 (2018)
BackgroundAbdominal aortic aneurysm (AAA) is a potentially life‐threatening disease that is common in older individuals. Currently, therapeutic options are limited to surgical interventions. Although it has long been known that AAA tissue is enrich
Externí odkaz:
https://doaj.org/article/9492db002dcb45b3a1cfd72148deaa27
Autor:
Satoko Ohno‐Urabe, Hiroki Aoki, Michihide Nishihara, Aya Furusho, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Hideo Yasukawa, Tsutomu Imaizumi, Hidetoshi Akashi, Hiroyuki Tanaka, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 2 (2018)
BackgroundAortic dissection (AD) is a life‐threatening medical emergency caused by the abrupt destruction of the intimomedial layer of the aortic walls. Given that previous studies have reported the involvement of proinflammatory cytokine interleuk
Externí odkaz:
https://doaj.org/article/cd499ab5c5b544cfb1f158a739decd87
Autor:
Michihide Nishihara, Hiroki Aoki, Satoko Ohno, Aya Furusho, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Tsutomu Imaizumi, Yoshihiro Fukumoto
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185923 (2017)
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence is accumulating to support a central role for inflammation. Inflammatory responses are coordinated by various soluble cytokines of which IL-6 is one of the major p
Externí odkaz:
https://doaj.org/article/12462ace24eb4b049d9036d97bc276c0
Publikováno v:
Journal of Cardiology. 77:471-474
Aortic dissection (AD) is a medical emergency, in which acute destruction of aortic wall occurs with unknown etiology. Recent studies have uncovered the critical role of inteleukin-6 (IL-6) and inflammatory cells including macrophages in the disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89630113fb1dcf77c4c0c0c2bb13697
https://doi.org/10.1016/j.jjcc.2020.10.010
https://doi.org/10.1016/j.jjcc.2020.10.010
Autor:
Hiroyuki Tanaka, Satoko Ohno-Urabe, Hiroki Aoki, Tsutomu Imaizumi, Sinichi Hiromatsu, Saki Hirakata, Makiko Hayashi, Yoshihiro Fukumoto, Sohei Ito, Aya Furusho, Norifumi Nishida, Michihide Nishihara, Hideo Yasukawa
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
Summary: Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e0c46afd4f4d1a9d0e7f16e9c345a8
https://doi.org/10.1016/j.jacbts.2019.10.010
https://doi.org/10.1016/j.jacbts.2019.10.010
Autor:
Eichi Nakao, Hiroki Aoki, Ryohei Majima, Youhei Hashimoto, Ryo Shibata, Makiko HAYASHI, Satoko Ohno, Aya Furusho, Norifumi Nishida, SAKI HIRAKATA, Yoshihiro Fukumoto
Publikováno v:
Circulation. 144
Background: Aortic dissection (AD) is a catastrophic disease that occurs suddenly. The acute mortality is high and those who survived frequently suffer from serious complications. Currently, pathogenesis of AD is largely unknown, which hampers the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f27f0df7ceb77b18fb38b9c7312477b
https://doi.org/10.1161/circ.144.suppl_1.12818
https://doi.org/10.1161/circ.144.suppl_1.12818
Autor:
Ryo Shibata, Norifumi Nishida, Ryohei Majima, Aya Furusho, Y Hashimoto, Hiroki Aoki, Saki Hirakata, Makiko Hayashi, Eichi Nakao, Yoshihiro Fukumoto, Satoko Ohno-Urabe
Publikováno v:
European Heart Journal. 42
Background Aortic dissection (AD) is a catastrophic disease that occurs suddenly. The acute mortality is high and those who survived frequently suffer from serious complications such as aneurysm formation and distal ischemia due to progressive destru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2400cf6402a2b8419ec002bef6304dc3
https://doi.org/10.1093/eurheartj/ehab724.3404
https://doi.org/10.1093/eurheartj/ehab724.3404
Autor:
Makiko Hayashi, Eichi Nakao, Yoshihiro Fukumoto, Ryohei Majima, Norifumi Nishida, Sohei Ito, Aya Furusho, Hiroki Aoki, Saki Hirakata, Y Hashimoto
Publikováno v:
European Heart Journal. 41
Background Aortic dissection (AD) is a serious clinical condition that frequently results in fatal outcome. Although recent studies indicate the critical role of inflammation in AD, the molecular pathogenesis of AD is still unclear. Syk is a tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fabe6ff9a552f93c2767566f7f42574a
https://doi.org/10.1093/ehjci/ehaa946.2312
https://doi.org/10.1093/ehjci/ehaa946.2312