Soluble and pelletable factors in porcine, canine and human notochordal cell-conditioned medium: implications for IVD regeneration

Autor: FC Bach, SAH de Vries, FM Riemers, J Boere, FWM van Heel, M van Doeselaar, SS Goerdaya, PGJ Nikkels, K Benz, LB Creemers, AF Maarten Altelaar, BP Meij, K Ito, MA Tryfonidou

Publikováno v: European Cells & Materials, Vol 32, Pp 163-180 (2016)

During intervertebral disc (IVD) maturation, notochordal cells (NCs) are replaced by chondrocyte-like cells (CLCs) in the nucleus pulposus, suggesting that NCs play a role in maintaining tissue health. Affirmatively, NC-conditioned medium (NCCM) exer

Externí odkaz: https://doaj.org/article/dd49067ba6dc45d48bab91803fd316f4

Notochordal cell matrix: An inhibitor of neurite and blood vessel growth?

Autor: de Vries SAH; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, Eindhoven, the Netherlands., van Doeselaar M; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, Eindhoven, the Netherlands., Meij BP; Faculty of Veterinary Medicine, Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, the Netherlands., Tryfonidou MA; Faculty of Veterinary Medicine, Department of Clinical Sciences of Companion Animals, Utrecht University, Utrecht, the Netherlands., Ito K; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, P.O. Box 513, Eindhoven, the Netherlands.; Department of Orthopaedics, University Medical Center, Utrecht, the Netherlands.

Publikováno v: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2018 Dec; Vol. 36 (12), pp. 3188-3195. Date of Electronic Publication: 2018 Aug 06.

Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside.

Autor: Bach FC; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., Tellegen AR; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., Beukers M; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., Miranda-Bedate A; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., Teunissen M; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., de Jong WAM; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., de Vries SAH; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, MB 5600, The Netherlands., Creemers LB; Department of Orthopedics, University Medical Centre Utrecht, Utrecht, 3584 CX, The Netherlands., Benz K; TETEC AG, Reutlingen 72770, Germany., Meij BP; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands., Ito K; Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, MB 5600, The Netherlands.; Department of Orthopedics, University Medical Centre Utrecht, Utrecht, 3584 CX, The Netherlands., Tryfonidou MA; Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, 3584 CM, The Netherlands.

Publikováno v: Oncotarget [Oncotarget] 2018 May 29; Vol. 9 (41), pp. 26507-26526. Date of Electronic Publication: 2018 May 29 (Print Publication: 2018).