Zobrazeno 1 - 10
of 16
pro vyhledávání: '"SAC, spindle assembly checkpoint"'
Kniha
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Autor:
Edmond Fleischer, Vincent Kam Wai Wong, Thorsten Berg, Sara Abdelfatah, Thomas Efferth, Anette Klinger, Li Jun Yang, Qi Huang, Sami Hamdoun, Henry Johannes Greten, Angela Berg
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 1021-1034 (2019)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Po
Publikováno v:
The Journal of Biological Chemistry
The clinical efficacy of docetaxel (DTX) in prostate cancer treatment is barely satisfactory due to diverse responses of the patients, including the development of resistance. Recently, aberrant androgen receptor (AR) signaling, including expression
Autor:
Hyewon Park, Hae-Young Kim, Chad Slawson, Victoria A. Hassebroek, Yoshiaki Azuma, Mizuki Azuma
Publikováno v:
The Journal of Biological Chemistry
Ewing sarcoma is a pediatric bone cancer that expresses the chimeric protein EWSR1/FLI1. We previously demonstrated that EWSR1/FLI1 impairs the localization of Aurora B kinase to the midzone (the midline structure located between segregating chromoso
Akademický článek
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Akademický článek
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Autor:
Batra PJ; Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, Maharashtra, India., Kumari A; Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, Maharashtra, India., Liao VWY; Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia., Hibbs DE; Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia., Groundwater PW; Sydney Pharmacy School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia., Panda D; Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, Maharashtra, India.; National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali 160062, Punjab, India.
Publikováno v:
Journal of biochemistry [J Biochem] 2023 Jul 31; Vol. 174 (2), pp. 143-164.
Autor:
Abdelfatah S; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz 55128, Germany., Berg A; Leipzig University, Institute of Organic Chemistry, Leipzig 04103, Germany., Huang Q; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China., Yang LJ; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China., Hamdoun S; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz 55128, Germany., Klinger A; MicroCombiChem GmbH, Wiesbaden 65203, Germany., Greten HJ; Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto 4099-003, Portugal., Fleischer E; MicroCombiChem GmbH, Wiesbaden 65203, Germany., Berg T; Leipzig University, Institute of Organic Chemistry, Leipzig 04103, Germany., Wong VKW; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China., Efferth T; Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz 55128, Germany.
Publikováno v:
Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2019 Sep; Vol. 9 (5), pp. 1021-1034. Date of Electronic Publication: 2019 Feb 10.
Autor:
Corkery DP; a Department of Biochemistry & Molecular Biology ; Dalhousie University ; Halifax , NS Canada., Le Page C, Meunier L, Provencher D, Mes-Masson AM, Dellaire G
Publikováno v:
Cell cycle (Georgetown, Tex.) [Cell Cycle] 2015; Vol. 14 (7), pp. 1059-69.
Autor:
Tarailo-Graovac M; a Department of Molecular Biology and Biochemistry ; Simon Fraser University ; Burnaby , BC Canada., Wong T, Qin Z, Flibotte S, Taylor J, Moerman DG, Rose AM, Chen N
Publikováno v:
Cell cycle (Georgetown, Tex.) [Cell Cycle] 2014; Vol. 13 (19), pp. 3089-199.