Zobrazeno 1 - 10
of 208
pro vyhledávání: '"S1PR3"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Background Inflammation and endothelial barrier dysfunction are the major pathophysiological changes in acute respiratory distress syndrome (ARDS). Sphingosine-1-phosphate receptor 3 (S1PR3), a G protein-coupled receptor, has been found to m
Externí odkaz:
https://doaj.org/article/32ffabffc0994b17887acc9802ed5d2f
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35532- (2024)
Background: Studies verified that sphingosine kinase 1 (SPHK1)/sphingosine 1-phosphate receptors (S1PRs) and platelet-derived growth factor receptors (PDGFRs) play important roles in tumor occurrence and progression. However, the expression and clini
Externí odkaz:
https://doaj.org/article/0718b802099a4639bd9605701da06f78
Autor:
Sagarika Chakrabarty, Quyen Bui, Leylla Badeanlou, Kelly Hester, Jerold Chun, Wolfram Ruf, Theodore P Ciaraldi, Fahumiya Samad
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 69-83 (2022)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that interacts via 5 G-protein coupled receptors, S1PR1-5, to regulate signalling pathways critical to biological processes including cell growth, immune cell trafficking, and inflammation.We
Externí odkaz:
https://doaj.org/article/b5842b2215f440ccb953cfdf3e9745aa
Autor:
Byunghyun Park, Yu Sun Jeong, Wonseok Hu, Mingyu Lee, Ji Cheol Kim, Geon Ho Bae, Yong-Soo Bae, Yoe-Sik Bae
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMultiple sclerosis (MS) is a potentially disabling disease that damages the brain and spinal cord, inducing paralysis of the body. While MS has been known as a T-cell mediated disease, recent attention has been drawn to the involvement of
Externí odkaz:
https://doaj.org/article/bc56a6f02ece46ceb48a44a6e4e17b12
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Anlin Feng, Wenli Ma, Reem Faraj, Gabriel T. Kelly, Stephen M. Black, Michael B. Fallon, Ting Wang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Background Sepsis is a life-threatening complication of infection that rapidly triggers tissue damage in multiple organ systems and leads to multi-organ deterioration. Up to date, prognostic biomarkers still have limitations in predicting th
Externí odkaz:
https://doaj.org/article/ee40b66ba78d4e5aa5a48af5d9dea403
Autor:
Xuehui Fan, Hongping Chen, Chen Xu, Yingju Wang, Pengqi Yin, Meng Li, Zhanbin Tang, Fangchao Jiang, Wan Wei, Jihe Song, Guozhong Li, Di Zhong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Ischemic stroke is the most common stroke incident. Sphingosine-1-phosphate (S1P) receptor 3 (S1PR3) is a member of the downstream G protein-coupled receptor family of S1P. The effect of S1PR3 on ischemic stroke remains elusive.Methods: W
Externí odkaz:
https://doaj.org/article/c2b0bc61f3744c2d85a4ba888a221579
Autor:
Xuehui Fan, Hongping Chen, Chen Xu, Yingju Wang, Pengqi Yin, Meng Li, Zhanbin Tang, Fangchao Jiang, Wan Wei, Jihe Song, Guozhong Li, Di Zhong
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
BackgroundIschemic stroke (IS) is a common disease endangering human life and health. Cerebral ischemia triggers a series of complex harmful events, including excitotoxicity, inflammation and cell death, as well as increased nitric oxide production t
Externí odkaz:
https://doaj.org/article/d890935a2ab448b48c3390ebe25c7f2c