Zobrazeno 1 - 10
of 79
pro vyhledávání: '"S1P2"'
Autor:
Hanye Liu, Liangchang Li, Zhengai Chen, Yilan Song, Weidong Liu, Ge Gao, Li Li, Jingzhi Jiang, Chang Xu, Guanghai Yan, Hong Cui
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
This study is to investigate the role of Sphingosine-1-phosphate (S1P) in the asthma progression, and the involvement of autophagy. Airway remodeling mice were subjected to the HE, PAS, and Masson staining. Protein expression levels in the tissues, s
Externí odkaz:
https://doaj.org/article/cc06dab7fb63423d876c1a747be7caa8
Autor:
Chi-Ho Lee, Ji Woong Choi
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1706 (2021)
The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases. Here, we provide experimental evidence supporting the regulatory role of sphingosine-1-phosphate (S1P) in NLRP3 inflammasome activation in mouse bone-marrow-deriv
Externí odkaz:
https://doaj.org/article/7e20c0f07dec4bf4ac2bcc30dcb53a7e
Autor:
Ganbaatar, Byambasuren, Fukuda, Daiju, Shinohara, Masakazu, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Hirata, Ken-ichi, Sata, Masataka
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 28(6):630-642
Aim: The bioactive lipid, sphingosine-1-phosphate (S1P), has various roles in the physiology and pathophysiology of many diseases. There are five S1P receptors; however, the role of each S1P receptor in atherogenesis is still obscure. Here we investi
Publikováno v:
Biomolecules, Vol 3, Iss 3, Pp 351-368 (2013)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that activates a family of G protein coupled-receptors (GPCRs) implicated in mammalian development, angiogenesis, immunity and tissue regeneration. S1P functions as a trophic factor for many c
Externí odkaz:
https://doaj.org/article/f8d9166f532145e896e4d16928b709b0
Autor:
Byambasuren Ganbaatar, Hirotsugu Yamada, Takeshi Soeki, Shusuke Yagi, Masataka Sata, Ken-ichi Hirata, Masakazu Shinohara, Daiju Fukuda, Kenya Kusunose
Publikováno v:
Journal of Atherosclerosis and Thrombosis
Aim: The bioactive lipid, sphingosine-1-phosphate (S1P), has various roles in the physiology and pathophysiology of many diseases. There are five S1P receptors; however, the role of each S1P receptor in atherogenesis is still obscure. Here we investi
Publikováno v:
Biomolecules & Therapeutics
Sphingosine-1-phosphate (S1P) and its receptors have been implicated in atopic dermatitis. S1P2 was found to function as a pro-allergic receptor, while its antagonist JTE-013 was found to suppress allergic asthma in mice. Topical application of JTE-0
Publikováno v:
Pharmaceuticals, Vol 4, Iss 1, Pp 117-137 (2011)
Atherosclerosis is a chronic inflammatory process involving complex interactions of modified lipoproteins, monocyte-derived macrophages or foam cells, lymphocytes, endothelial cells (ECs), and vascular smooth muscle cells. Sphingosine-1-phosphate (S1
Externí odkaz:
https://doaj.org/article/e1202cd23e6a4cf38ccb52c637091d1a
Akademický článek
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Autor:
Ji Woong Choi, Chi-Ho Lee
Publikováno v:
Antioxidants, Vol 10, Iss 1706, p 1706 (2021)
Antioxidants
Volume 10
Issue 11
Antioxidants
Volume 10
Issue 11
The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases. Here, we provide experimental evidence supporting the regulatory role of sphingosine-1-phosphate (S1P) in NLRP3 inflammasome activation in mouse bone-marrow-deriv
Autor:
Chi-Ho, Lee, Ji Woong, Choi
Publikováno v:
Antioxidants
The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases. Here, we provide experimental evidence supporting the regulatory role of sphingosine-1-phosphate (S1P) in NLRP3 inflammasome activation in mouse bone-marrow-deriv