Zobrazeno 1 - 10
of 69
pro vyhledávání: '"S.V. Girman"'
Autor:
Peter G. Schultz, V. Deshmukh, Jonathan G. Swoboda, Shaomei Wang, Weijun Shen, Bin Lu, Matthew S. Tremblay, Charles Y. Cho, Eric C. Peters, Jimmy Elliott, S.V. Girman, Lorenzo de Lichtervelde
Publikováno v:
ACS Chemical Biology. 8:1407-1411
Retinal pigment epithelial (RPE) cells form a monolayer adjacent to the retina and play a critical role in the visual light cycle. Degeneration of RPE cells results in retinal disorders such as age-related macular degeneration. Cell transplant strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2e49978617311bb93b24a5c0a9f7bd
https://doi.org/10.1021/cb4001712
https://doi.org/10.1021/cb4001712
Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration
Autor:
R. D. Lund, Benjamin Cottam, Trevor J. McGill, Chunyu Tian, Stephen L. Huhn, Shaomei Wang, S.V. Girman, Alexandra Capela, Bin Lu
Publikováno v:
European Journal of Neuroscience. 35:468-477
Stem cells derived from the human brain and grown as neurospheres (HuCNS-SC) have been shown to be effective in treating central neurodegenerative conditions in a variety of animal models. Human safety data in neurodegenerative disorders are currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6082a25b6f62d45ae5cba2c214215bf1
https://doi.org/10.1111/j.1460-9568.2011.07970.x
https://doi.org/10.1111/j.1460-9568.2011.07970.x
Autor:
R. D. Lund, S.V. Girman
Publikováno v:
Journal of Neurophysiology. 98:161-177
The uppermost layer (stratum griseum superficiale, SGS) of the superior colliculus (SC) provides an important gateway from the retina to the visual extrastriate and visuomotor systems. The majority of attention has been given to the role of this “v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13535a6223d8b23f389034638eb34340
https://doi.org/10.1152/jn.00059.2007
https://doi.org/10.1152/jn.00059.2007
Autor:
Irina Klimanskaya, Bin Lu, S.V. Girman, Shaomei Wang, Robert Lanza, N. Bischoff, Toby Holmes, Rebeca Ramos-Kelsey, Raymond D. Lund, Yves Sauve
Publikováno v:
Cloning and Stem Cells. 8:189-199
Embryonic stem cells promise to provide a well-characterized and reproducible source of replacement tissue for human clinical studies. An early potential application of this technology is the use of retinal pigment epithelium (RPE) for the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49db49cd68852c677f405a4f5e069c8
https://doi.org/10.1089/clo.2006.8.189
https://doi.org/10.1089/clo.2006.8.189
Publikováno v:
Vision Research. 45(3):343-354
To examine how rod and cone function are differentially affected during retinal degeneration, and after subretinal cell grafting, we obtained light- and dark-adaptation curves by recording threshold multiunit responses from the superior colliculus of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09eaaf4a3f4ba21ea303bb039d2fa09e
Autor:
S.V. Girman, Raymond D. Lund
Publikováno v:
Visual Neuroscience. 22:37-43
In the Royal College of Surgeons, rat photoreceptor degeneration occurs over the first several months of life, causing deterioration of visual cortical responsiveness seen as greater numbers of cells being nonresponsive to visual stimulation, poor tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9250f670ebabc31daba1a1cf0c3e0b98
https://doi.org/10.1017/s0952523805221041
https://doi.org/10.1017/s0952523805221041
Publikováno v:
Neuroscience. 114:389-401
The dystrophic RCS rat undergoes progressive photoreceptor degeneration due to a primary defect in retinal pigment epithelial (RPE) cells. This has a major impact on central visual responsiveness. Here we have examined how functional deterioration is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c8b25367b0f5b0d590b5d816e7b2e4
https://doi.org/10.1016/s0306-4522(02)00271-3
https://doi.org/10.1016/s0306-4522(02)00271-3
Autor:
Peter J. Coffey, A Zerbib, Laurence Beauchéne, Raymond D. Lund, Yves Sauve, Peter Adamson, Helen L Winton, John Greenwood, Len Hetherington, Pierre-Olivier Couraud, Anthony S. L. Kwan, David J Keegan, S.V. Girman, Shaomei Wang, Naheed Kanuga
Publikováno v:
Proceedings of the National Academy of Sciences. 98:9942-9947
Royal College of Surgeons rats are genetically predisposed to undergo significant visual loss caused by a primary dysfunction of retinal pigment epithelial (RPE) cells. By using this model, we have examined the efficacy of subretinal transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8701ffc32ddef1dbd0a31407ba83e46
https://doi.org/10.1073/pnas.171266298
https://doi.org/10.1073/pnas.171266298
Autor:
S.V. Girman
Publikováno v:
Neuroscience. 60:989-997
Electrophysiological and anatomical studies were carried out in parallel to investigate the ability of lateral geniculate body neurons to regenerate axons damaged by the removal of the primary visual cortex and to innervate graft neurons functionally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d066213826f112c701fcb2250d6002
https://doi.org/10.1016/0306-4522(94)90278-x
https://doi.org/10.1016/0306-4522(94)90278-x
Autor:
R. D. Lund, S.V. Girman
Publikováno v:
Journal of neurophysiology. 104(6)
In the primary visual cortex (V1), it has been shown that the neuronal response elicited by a grating patch in the receptive field (RF) center can be suppressed or facilitated by an annular grating presented in the RF surround area; the effect depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281f0b818488dcddeffb7d9d7e2a9fa7
https://pubmed.ncbi.nlm.nih.gov/20861426
https://pubmed.ncbi.nlm.nih.gov/20861426