Zobrazeno 1 - 10
of 128
pro vyhledávání: '"S.T. Dheen"'
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:2073-2087
The interplay between implant design, biomaterial characteristics, and the local microenvironment adjacent to the implant is of utmost importance for implant performance and success of the joint replacement surgery. Reactive oxygen and nitrogen speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4a97584dad254febb0b9a58dd35ed8
https://doi.org/10.1002/jbm.b.34546
https://doi.org/10.1002/jbm.b.34546
Autor:
Senthil Kumar Anantharajan, S.T. Dheen, Silambarasan Maskomani, Niyou Wang, Ganesh Kumar Meenashisundaram, Jerry Y. H. Fuh
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 117
Hybrid implants combine both Titanium (Ti) and Magnesium (Mg) are prevalent nowadays. The long-term implications of Ti and Mg implants within the human body are not yet fully understood. Many implant failure cases due to inflammation, allergic respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4e0d7e8a68138a2fe7c8c99f84b3e7
https://pubmed.ncbi.nlm.nih.gov/32919646
https://pubmed.ncbi.nlm.nih.gov/32919646
Publikováno v:
Aging Cell
Progressive memory loss is one of the most common characteristics of Alzheimer's disease (AD), which has been shown to be caused by several factors including accumulation of amyloid β peptide (Aβ) plaques and neurofibrillary tangles. Synaptic plast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaf4631568007cf80fcafe3468b0b9e
https://pubmed.ncbi.nlm.nih.gov/31625272
https://pubmed.ncbi.nlm.nih.gov/31625272
Publikováno v:
NeuroMolecular Medicine. 18:453-464
Chronic neuroinflammation is a pathological feature of a number of central nervous system (CNS) diseases and is mediated by sustained activation of microglial cells, the innate immune cells of the CNS. Studies have mainly focused on identifying the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038315f3c24e20725cd0ba43e9c0be60
https://doi.org/10.1007/s12017-016-8430-x
https://doi.org/10.1007/s12017-016-8430-x
Publikováno v:
Neuroscience. 311:398-414
Microglia are the prime cellular sources of reactive oxygen species (ROS) in the central nervous system (CNS). Chronic activation of microglia has been linked to aging-associated neurodegenerative diseases such as Alzheimer's disease (AD) and Parkins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc00300e0ab02bd0dd732168d0977542
https://doi.org/10.1016/j.neuroscience.2015.10.048
https://doi.org/10.1016/j.neuroscience.2015.10.048
Autor:
Niyou Wang, S.T. Dheen, Ganesh Kumar Meenashisundaram, Silambarasan Maskomani, Sharon Mui Ling Nai, Shenglu Lu, Jerry Y. H. Fuh, Senthil Kumar Anantharajan, Jun Wei
Publikováno v:
Materials Science and Engineering: C. 108:110478
A semi-degradable Ti + Mg composite with superior compression and cytotoxicity properties have been successfully fabricated using ink jet 3D printing followed by capillary mediated pressureless infiltration technique targeting orthopaedic implant app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269c4832ca7767fc9441601daf8fbf96
https://doi.org/10.1016/j.msec.2019.110478
https://doi.org/10.1016/j.msec.2019.110478
Publikováno v:
Current medicinal chemistry. 26(25)
Background: Preeclapmsia (PE) is characterized by early onset symptoms such as elevated blood pressure, proteinuria and edema in the pregnant woman, and may result in seizures in the affected female. Currently, there are no therapeutic drugs availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51400284aaba4d35f7204c546feb999
https://pubmed.ncbi.nlm.nih.gov/30836908
https://pubmed.ncbi.nlm.nih.gov/30836908
Akademický článek
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Publikováno v:
Current Medicinal Chemistry. 21:4215-4226
Nanomedicine, an emerging therapeutic tool in current medical frontiers, offers targeted drug delivery for many neurodegenerative disorders. Neuroinflammation, a hallmark of many neurodegenerative disorders, is mediated by microglia, the resident imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be88961e80295952c5f3fbf4d1febf3
https://doi.org/10.2174/0929867321666140716101258
https://doi.org/10.2174/0929867321666140716101258
Autor:
D. Nayak, Srinivasan Dinesh Kumar, Eng-Ang Ling, Y. Huo, Peter Natesan Pushparaj, S.T. Dheen, W.X.T. Kwang
Publikováno v:
Neuroscience. 166:132-144
Microglial activation has been implicated as one of the causative factors for neuroinflammation in various neurodegenerative diseases. The sphingolipid metabolic pathway plays an important role in inflammation, cell proliferation, survival, chemotaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac551861a47adc22f0622edf43c1575
https://doi.org/10.1016/j.neuroscience.2009.12.020
https://doi.org/10.1016/j.neuroscience.2009.12.020