Zobrazeno 1 - 10
of 122
pro vyhledávání: '"S.S. Kerwar"'
Publikováno v:
Archives of Biochemistry and Biophysics. 159:880-884
Free and membrane bound polysomes were prepared from 8-day-old chick embryos. Both polysome preparations were equally active in protein synthesis but procollagen-collagen synthesis was carried out exclusively by the membrane bound polysomes. The coll
Publikováno v:
Biochemical and Biophysical Research Communications. 66:1275-1280
Various proline analogs were examined for their effect on the activity of prolyl hydroxylase in L-929 fibroblasts. Of the analogs tested, L-3,4-dehydroproline and L-azetidine-2-carboxylic acid were effective in reducing the activity of prolyl hydroxy
Autor:
A.L. Oronsky, S.S. Kerwar
Publikováno v:
Advances in Enzyme Regulation. 29:247-265
The present studies have shown that low doses of methotrexate can suppress the inflammation and joint destruction associated with animal models of arthritis. The antiinflammatory effects of methotrexate are probably related to its inhibitory effect o
Autor:
S.S. Kerwar
Publikováno v:
Archives of Biochemistry and Biophysics. 163:609-613
Analysis of pro-α chains released from chick embryo membrane polysomes indicates that they are not disulfide bonded and have a molecular weight of approximately 120,000. Therefore, disulfide bonding which has been observed between pro-α chains is n
Publikováno v:
Archives of Biochemistry and Biophysics. 116:305-318
Methionine synthetase, an enzyme that catalyzes the terminal reaction in the biosynthesis of methionine (5-methyl tetrahydrofolate + homocysteine → tetrahydrofolate + methionine), has been partially purified from pig liver, beef liver, and Escheric
Autor:
Herbert Weissbach, S.S. Kerwar
Publikováno v:
Archives of Biochemistry and Biophysics. 141:525-532
It has been previously shown that norleucine can acylate both tRNAFMet and tRNAFMet and be converted to fNorleu-tRNAFMet. The present studies have compared the reactivity of fNorleu-tRNAFMet with fMet-tRNAFMet in various reactions associated with pro
Publikováno v:
Archives of Biochemistry and Biophysics. 142:231-237
In the present report some aspects of vitamin B 12 metabolism in HeLa cells and other tissue culture lines have been investigated. Mangum et al . (1) previously reported the presence of higher levels of N 5 -methyl- H 4 -folate-homocysteine transmeth
Publikováno v:
Proceedings of the National Academy of Sciences. 70:1378-1382
A cell-free system that actively synthesizes collagen was prepared from L-929 fibroblasts. Chromatographic and electrophoretic techniques were used to demonstrate that the only collagenous products are pro α 1 and pro α 2 chains. The collagen synth
Publikováno v:
Journal of Biological Chemistry. 245:1169-1174
An analogue of vitamin B12 coenzyme in which the ribosyl oxygen has been replaced by —CH2— has been synthesized. This compound has spectral properties very similar to vitamin B12 coenzyme. The chemical properties of the analogue differ from those
Publikováno v:
Archives of biochemistry and biophysics. 182(1)
Hepatic fibrosis in rats was induced by chronic subcutaneous treatment with carbon tetrachloride. The amount of collagen and the specific activity of prolyl hydroxylase were greatly enhanced. On treatment of these fibrotic animals with dl -3,4-dehydr