Zobrazeno 1 - 10
of 82
pro vyhledávání: '"S.N. Suryawanshi"'
Autor:
S.N. Suryawanshi, Suman Gupta, Avinash Tiwari, Susmita Pandey, Yashpal S. Chhonker, Rabi Sankar Bhatta, Rahul Shivahare, Nishi Shakya, Santosh Kumar
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:3979-3982
A series of aryl S , N -ketene acetals 7(a – f) was synthesized and evaluated for their in vitro and in vivo antileishmanial activity against Leishmania donovani . All the 6 compounds exhibited significant in vitro activity against intracellular am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae3de92214b2bd63c517822392bc472
https://doi.org/10.1016/j.bmcl.2013.04.025
https://doi.org/10.1016/j.bmcl.2013.04.025
Autor:
Avinash Tiwari, Rahul Shivahare, Suman Gupta, Monika Mittal, Santosh Kumar, S.N. Suryawanshi, Padam Kant
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2925-2928
A novel series of triazole integrated phenyl heteroterpenoids have been synthesized and screened for their in vitro activity against intracellular amastigote form of Leishmania donovani. Among all tested compounds, compound 3a was found to be the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edfe75128971be9656c25d813ddecbd
https://doi.org/10.1016/j.bmcl.2013.03.055
https://doi.org/10.1016/j.bmcl.2013.03.055
Publikováno v:
European Journal of Medicinal Chemistry. 43:2473-2478
Some novel dihydro-alpha-ionone based chalcones have been synthesized and evaluated for their in vitro antileishmanial activity in promastigote and amastigote model. Some of the compounds showed 100% inhibition at 5 and 2 microm/ml concentration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5713897784541a30fe51abd663d6bb
https://doi.org/10.1016/j.ejmech.2007.12.014
https://doi.org/10.1016/j.ejmech.2007.12.014
Publikováno v:
European Journal of Medicinal Chemistry. 42:1211-1217
Some novel 4-N-substituted terpenyl pyrimidines 5(a-d) and 7(a-g) have been synthesized using novel synthetic methods. The compounds were screened for in vivo antileishmanial screening. When compared to 4-thiomethoxy substituted pyrimidine 2 4-N-subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ee71608462d8da4fe8d6a1f746003d
https://doi.org/10.1016/j.ejmech.2006.10.002
https://doi.org/10.1016/j.ejmech.2006.10.002
Publikováno v:
European Journal of Medicinal Chemistry. 42:669-674
Some novel 2-substituted pyridinone derivatives exemplified by 3 and 4 have been synthesized from 2-methyl-gamma-pyrone and screened towards in vitro antileishmanial activity profile. Some of the compounds such as 3a, 3b, 4i and 4j displayed good ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b3d1cfde636277337f74274b9c2680
https://doi.org/10.1016/j.ejmech.2006.11.011
https://doi.org/10.1016/j.ejmech.2006.11.011
Publikováno v:
European Journal of Medicinal Chemistry. 41:779-785
Some aryl substituted terpenyl pyrimidines 4 (a-p) have been synthesized using novel synthetic methods. The compounds were screened for in vitro antileishmanial activity against promastigotes. Compounds 4c, 4i and 4l showed IC(50) values as 35, 35 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532f20c0c18de6db8ce582f3896d611a
https://doi.org/10.1016/j.ejmech.2006.02.004
https://doi.org/10.1016/j.ejmech.2006.02.004
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(2)
Some novel heteroretinoid-bisbenzylidine ketone hybrids have been synthesized and evaluated for their in vitro antileishmanial activity against intramacrophagic amastigotes of Leishmania donovani. Among all the nine synthetic compounds, five compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebeeaaf5e50bf3daef198249421ac61
https://pubmed.ncbi.nlm.nih.gov/25475205
https://pubmed.ncbi.nlm.nih.gov/25475205
Autor:
Santosh Kumar, Suman Gupta, Avinash Tiwari, Rahul Shivahare, Susmita Pandey, S.N. Suryawanshi
Publikováno v:
ChemInform. 45
Compound (IIIc) exhibits a significant inhibition of parasitic multiplication of 88.4% at a daily dosis of 50mg/kg x 5 days when administered intraperitoneally.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eedd3a4f4018180109d3a50c162a383
https://doi.org/10.1002/chin.201404165
https://doi.org/10.1002/chin.201404165
Autor:
Avinash Tiwari, Susmita Pandey, S.N. Suryawanshi, Suman Gupta, Rahul Shivahare, Santosh Kumar
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(18)
A series of substituted aryl pyrimidine derivatives was synthesized and evaluated in vitro for their antileishmanial potential against intracellular amastigotes of Leishmania donovani using reporter gene luciferase assay. Among all, 8 compounds showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e5ef7f852a0b464fca03282ca87cf6
https://pubmed.ncbi.nlm.nih.gov/23910597
https://pubmed.ncbi.nlm.nih.gov/23910597
Publikováno v:
ChemInform. 44
Heteroretinoid (Ib) and its amide (Ic-i) are synthesized and screened for their in vivo antileishmanial activity against Leishmania donovani in hamsters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c3e0152250f71da0f5e5798f6cb5086
https://doi.org/10.1002/chin.201311129
https://doi.org/10.1002/chin.201311129