Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S.M. Touhidul Islam"'
Publikováno v:
Annals of Hepatology, Vol 19, Iss 5, Pp 466-471 (2020)
Nonalcoholic steatohepatitis (NASH) is a form of fatty liver disease where benign hepatic steatosis leads to chronic inflammation in the steatotic liver of a patient without any history of alcohol abuse. Mechanisms underlying the progression of hepat
Externí odkaz:
https://doaj.org/article/2be10c1b8896449ea07d38510645352b
Autor:
Judong Kim, S.M. Touhidul Islam, Fei Qiao, Avtar K. Singh, Mushfiquddin Khan, Jeseong Won, Inderjit Singh
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102053- (2021)
B cells play both protective and pathogenic roles in T cell-mediated autoimmune diseases by releasing regulatory vs. pathogenic cytokines. B cell-depleting therapy has been attempted in various autoimmune diseases but its efficacy varies and can even
Externí odkaz:
https://doaj.org/article/5657e3a2eabc468db40de747b2a899b1
Autor:
Seungho Choi, Je-Seong Won, Judong Kim, S.M. Touhidul Islam, Inderjit Singh, Nishant Saxena, Avtar K. Singh, Mushfiquddin Khan
Publikováno v:
Immunology
Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase (NOS) inhibitor/uncoupler inducing vascular pathology. Vascular pathology is an important factor for the development and progression of CNS pathology of MS, yet the role of ADM
Publikováno v:
Immunology
Hypoxia‐inducible factor‐1 (HIF‐1) is a heterodimeric (HIF‐1α/ HIF‐1β) transcription factor in which the oxygen‐sensitive HIF‐1α subunit regulates gene transcription to mediate adaptive tissue responses to hypoxia. HIF‐1 is a key m
Autor:
Judong Kim, Mushfiquddin Khan, S.M. Touhidul Islam, Inderjit Singh, Avtar K. Singh, Fei Qiao, Je-Seong Won
Publikováno v:
Neuroscience. 458:31-42
Reactive aldehydes are generated as a toxic end-product of lipid peroxidation under inflammatory oxidative stress condition which is a well-established phenomenon in the pathogenesis of multiple sclerosis (MS) and its animal model, experimental autoi
Autor:
Fei Qiao, Avtar K. Singh, Mushfiquddin Khan, Judong Kim, Inderjit Singh, S.M. Touhidul Islam, Je-Seong Won
Publikováno v:
Redox Biology
Redox Biology, Vol 45, Iss, Pp 102053-(2021)
Redox Biology, Vol 45, Iss, Pp 102053-(2021)
B cells play both protective and pathogenic roles in T cell-mediated autoimmune diseases by releasing regulatory vs. pathogenic cytokines. B cell-depleting therapy has been attempted in various autoimmune diseases but its efficacy varies and can even
Autor:
Mushfiquddin Khan, Pavan Kumar, Je-Seong Won, Avtar K. Singh, S.M. Touhidul Islam, Inderjit Singh, Fei Qiao
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 1, Pp 185-193 (2022)
Neural Regeneration Research
Neural Regeneration Research
Spinal cord injury (SCI) is associated with high production and excessive accumulation of pathological 4-hydroxy-trans-2-nonenal (4-HNE), a reactive aldehyde, formed by SCI-induced metabolic dysregulation of membrane lipids. Reactive aldehyde load ca
Background Experimental autoimmune encephalomyelitis (EAE) is the most commonly used animal model for human multiple sclerosis (MS), a demyelinating autoimmune disease mediated by T and B lymphocytes. The aim of the present study was to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d78479bfd75e0f48fe3fa7a1e7cea79
https://doi.org/10.21203/rs.3.rs-75440/v1
https://doi.org/10.21203/rs.3.rs-75440/v1
Autor:
Wayne Feng, Mushfiquddin Khan, Fei Qiao, Inderjit Singh, Avtar K. Singh, S.M. Touhidul Islam, Je-Seong Won, Pavan Kumar
Publikováno v:
Brain research. 1741
The nitric oxide (NO) metabolome and the NO metabolite-based neurovascular protective pathways are dysregulated after stroke. The major NO metabolite S-nitrosoglutahione (GSNO) is essential for S-nitrosylation-based signaling events and the inhibitio
Autor:
Je-Seong Won, Avtar K. Singh, Fei Qiao, Mushfiquddin Khan, Inderjit Singh, S.M. Touhidul Islam, Tajinder S Dhammu, Pavan Kumar
Publikováno v:
Brain Res
Traumatic spinal cord injury (SCI) enhances the activity of S-nitrosoglutathione reductase (GSNOR) and inhibits the mitochondrial aldehyde dehydrogenase 2 (ALDH2) activity, resulting in prolonged and sustained pain and functional deficits. This study