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The Cholesterol-Raising Factor from Coffee Beans, Cafestol, as an Agonist Ligand for the Farnesoid and Pregnane X Receptors

Autor: Mark V. Boekschoten, Corina J. A. Moen, Martijn B. Katan, David D. Moore, J. Gordon Porter, Arja J. Kreeft, Marten H. Hofker, Michael Müller, Soemini Kasanmoentalib, Rune R. Frants, S.M. Post, Marie-Louise Ricketts, Guido J. E. J. Hooiveld, Hans M.G. Princen

Publikováno v: Molecular endocrinology, 21(7), 1603-1616. ENDOCRINE SOC
Molecular endocrinology, 21(7), 1603-1616
Molecular Endocrinology, 21(7), 1603-1616. The Endocrine Society
Molecular endocrinology 21 (2007) 7
Ricketts, M L, Boekschoten, M V, Kreeft, A J, Hooiveld, G J, Moen, C J, Müller, M, Frants, R R, Kasanmoentalib, S, Post, S M, Princen, H M G, Porter, J G, Katan, M B, Hofker, M H & Moore, D D 2007, ' The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane x receptors ', Molecular Endocrinology, vol. 21, no. 7, pp. 1603-1616 . https://doi.org/10.1210/me.2007-0133
Molecular Endocrinology, 21(7), 1603-1616. Endocrine Society

Cafestol, a diterpene present in unfiltered coffee brews such as Scandinavian boiled, Turkish, and cafetiere coffee, is the most potent cholesterol-elevating compound-knownin the human diet. Several genes involved in cholesterol homeostasis have prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03fd41ea2d7012ad8490d706a9cdc5e
https://doi.org/10.1210/me.2007-0133

Increased Fecal Bile Acid Excretion in Transgenic Mice With Elevated Expression of Human Phospholipid Transfer Protein

Autor: Hans M.G. Princen, Rien van Haperen, Arie van Tol, Rini de Crom, S.M. Post

Publikováno v: Arteriosclerosis Thrombosis & Vascular Biology, 23, 892-897. Lippincott Williams & Wilkins
Arteriosclerosis, Thrombosis, and Vascular Biology, 5, 23, 892-897

Objective— HDL plays a key role in protection against development of atherosclerosis by promoting reverse cholesterol transport from peripheral tissues to the liver for secretion into bile. Phospholipid transfer protein (PLTP) promotes the transfer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3d08bda369d82c541554bb954b92fd
https://doi.org/10.1161/01.atv.0000067702.22390.20