Zobrazeno 1 - 10
of 685
pro vyhledávání: '"S.J. Stohs"'
Publikováno v:
Toxicology Reports, Vol 4, Iss , Pp 598-613 (2017)
Bitter orange (Citrus aurantium L.) extracts are widely used in dietary supplements and bitter oranges are used in various juices and food products. p-Synephrine, the primary active constituent, comprises approximately 90% of total protoalkaloids. Th
Externí odkaz:
https://doaj.org/article/cb5aa5e9a2af42d2812b7dbdd5ceead7
Publikováno v:
Regulatory Toxicology and Pharmacology. 90:318-327
The primary active constituent in bitter orange extract (BOE) is p-synephrine. This study assessed the safety of a BOE standardized to 50% p-synephrine following short-term exposure to rats and by the Ames Test. Following 5000 mg/kg of the extract or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265598d1437cd161aa0a49632a122fe5
https://doi.org/10.1016/j.yrtph.2017.09.027
https://doi.org/10.1016/j.yrtph.2017.09.027
Autor:
S.J. Stohs
Polychlorinated biphenyls (PCBs) are a group of related toxic substances that have been produced intentionally and unintentionally. Exposure occurs through food, water, the atmosphere, and accidental contact. Toxicities demonstrated in animal studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::875c89746d51d02b597b18e084024061
https://doi.org/10.1016/b978-0-12-386454-3.00347-x
https://doi.org/10.1016/b978-0-12-386454-3.00347-x
Autor:
S.J. Stohs, N.Z. Alsharif
Publikováno v:
Chemosphere. 25:899-904
The toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD] and its bioisosteres involves binding to a specific TCDD [Ah] receptor, interaction of this complex with chromatin, and the ultimate production of a pleiotropic response. We have hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6bdee3abdbaf29abd4ecc48ae8e971
https://doi.org/10.1016/0045-6535(92)90082-3
https://doi.org/10.1016/0045-6535(92)90082-3
Autor:
M. Bagchi, S.J. Stohs
Publikováno v:
Chemosphere. 25:905-909
Polyhalogenated cyclichydrocarbons [PCH] including 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD], endrin and lindane [hexachlorocyclohexane] are potent toxins and tumor promoters. Recent studies have shown that these xenobiotics produce an oxidative str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fafa7b90e76b1045969d2c47bb7b9a9f
https://doi.org/10.1016/0045-6535(92)90083-4
https://doi.org/10.1016/0045-6535(92)90083-4
Publikováno v:
Toxicon. 30:977-984
The ability of ricin, the glycoprotein toxin from the castor bean (Ricinus communis), to stimulate oxidative stress was investigated. Following the i.p. administration of 25 μg ricin/kg or the vehicle to female CF-1 mice, the effects of ricin on hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0120837f8f56a07950c7828598ad50
https://doi.org/10.1016/0041-0101(92)90042-4
https://doi.org/10.1016/0041-0101(92)90042-4
Autor:
F.H. Lin, George W. Lucier, S.J. Stohs, Joyce A. Goldstein, Linda S. Birnbaum, George C. Clark
Publikováno v:
Toxicology and Applied Pharmacology. 108:129-139
The present study examines the role of the Ah receptor in the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the binding capacity of the hepatic glucocorticoid (GC) and estrogen (E) receptors in female congenic C57BL/6J mice differing only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df76a89692997160281fc13660cb88b3
https://doi.org/10.1016/0041-008x(91)90276-k
https://doi.org/10.1016/0041-008x(91)90276-k
Autor:
Y.H. Tahseen, S.J. Stohs, S.H. Majeed, M.J. Mahmoud, F.A. Shihab, Dennis H. Robinson, F.W. Ezzedeen
Publikováno v:
International Journal of Pharmaceutics. 59:255-261
The in vitro dissolution, in vitro absorption and in vivo absorption characteristics of Sulfamethoxazole (SMZ) and trimethoprim (TMP) from four commercially available oral suspensions have been studied. In vitro dissolution and absorption profiles fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0b277594233d0fcdd6fdfeb09b5131
https://doi.org/10.1016/0378-5173(90)90116-l
https://doi.org/10.1016/0378-5173(90)90116-l
Publikováno v:
Pharmacology. 41:231-236
Microcystin-LR (MCLR) is a potent cyclic heptapeptide hepatotoxin that is produced by the blue-green algae, Microcystis aeruginosa. This organism forms blooms in freshwater lakes and ponds. Following ingestion of contaminated waters, deaths of wildli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1954772af191a3d60696c50af5de479b
https://doi.org/10.1159/000138723
https://doi.org/10.1159/000138723
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