Zobrazeno 1 - 10
of 37
pro vyhledávání: '"S.J. Kaczmarczyk"'
Publikováno v:
Metabolism. 45:622-626
Increased hepatic glucose production, a feature of (non-insulin-dependent diabetes mellitus [NIDDM]), is present at an early age in the New Zealand Obese (NZO) mouse and is associated with impaired suppression of the gluconeogenic enzyme, fructose-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc228f11451844ef099267bc13f52aa5
https://doi.org/10.1016/s0026-0495(96)90034-7
https://doi.org/10.1016/s0026-0495(96)90034-7
Autor:
G. Rosella, Joseph Proietto, S.J. Kaczmarczyk, Jeffrey D Zajac, Louise Baker, Timothy E. Adams, Sofianos Andrikopoulos
Publikováno v:
Molecular Endocrinology. 9:1396-1404
The effects of an overexpressed, non-insulin-responsive gluconeogenic enzyme, phosphoenolpyruvate carboxykinase (GTP) (PEPCK; EC 4.1.1.32), on glucose homeostasis were investigated. Transgenic rats harboring a metallothionein-driven PEPCK gene (lacki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a0b49b711526d2b7f6789fb07eb511
https://doi.org/10.1210/mend.9.10.8544847
https://doi.org/10.1210/mend.9.10.8544847
Autor:
Anne W. Thorburn, Joseph Proietto, Elizabeth Gaskin, S.J. Kaczmarczyk, G. Rosella, Jeffrey D Zajac, Sofianos Andrikopoulos
Publikováno v:
Diabetes. 42:1731-1736
The New Zealand obese mouse, a model of NIDDM, is characterized by hyperglycemia, hyperinsulinemia, and hepatic and peripheral insulin resistance. The aim of this study was to investigate the biochemical basis of hepatic insulin resistance in NZO mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e49c89c5c325386cc14f68223c4c0f6
https://doi.org/10.2337/diabetes.42.12.1731
https://doi.org/10.2337/diabetes.42.12.1731
Publikováno v:
Molecular Endocrinology. 7:1456-1462
Despite detailed knowledge of the regulation of individual steps in the gluconeogenic pathway, the relative importance of each step to the overall control of gluconeogenesis by insulin is not known. The aim of this study was to determine the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871b914178f0325401813524545334ca
https://doi.org/10.1210/mend.7.11.8114759
https://doi.org/10.1210/mend.7.11.8114759
Autor:
John Y F Wong, Gavin Fabinyi, S.J. Kaczmarczyk, Frederick A.O. Mendelsohn, David W. Howells, Geoffrey A. Donnan, Peter J. Chilcho
Publikováno v:
Brain Research. 622:285-288
To test the hypothesis that proliferation of host dopaminergic tissue in response to injury plays an important role in the response to intrastriatal grafting, we transplanted autologous adrenal medullary to striatum in normal C57-black mice and compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de64a9edc09861dba3f9329bcc57f3a
https://doi.org/10.1016/0006-8993(93)90830-g
https://doi.org/10.1016/0006-8993(93)90830-g
Autor:
George Paxinos, D G Woodhouse, A J Churchyard, R. M. Kalnins, Gavin Fabinyi, Frederick A. O. Mendelsohn, Geoffrey A. Donnan, S.J. Kaczmarczyk, J E Holder, P J Chilco
Publikováno v:
Molecular Neurobiology. 5:421-433
A series of compensatory mechanisms within the dopaminergic system have been shown to maintain clinical function in the presence of dopamine loss. Experimental evidence for increased presynaptic dopamine turnover owing to increased dopamine synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd50b3ff8ed7ea78b1bce895b6d1e0f7
https://doi.org/10.1007/bf02935563
https://doi.org/10.1007/bf02935563
Autor:
V. Grill, G.M.F Pasquini, Rachel A Davey, S.J. Kaczmarczyk, Patricia W. M. Ho, Jeffrey D Zajac, V.P Michelangeli
Publikováno v:
Bone. 31(5)
Parathyroid hormone-related protein (PTHrP) has been implicated as being important in the growth of tumor cells responsive to the peptide. We utilized a rat osteoblastic osteosarcoma cell line, UMR 106-01, which has PTHrP receptors and a PTHrP-respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2318c2268a327f7d01aac7f109ce4de
https://pubmed.ncbi.nlm.nih.gov/12477574
https://pubmed.ncbi.nlm.nih.gov/12477574
Publikováno v:
Molecular and cellular endocrinology. 94(1)
Transcriptional regulation of the human parathyroid hormone-related protein (PTHrP) gene by calcitonin was examined in a lung cancer line (BEN cells). Northern analysis demonstrated that calcitonin caused a rapid 4.5-fold elevation in PTHrP mRNA. Tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f2f9b9d2ce71b12bc1fb2e35db2c48
https://pubmed.ncbi.nlm.nih.gov/7690720
https://pubmed.ncbi.nlm.nih.gov/7690720
Autor:
S.J. Kaczmarczyk, Geoffrey A. Donnan, Peter J. Chilco, R. M. Kalnins, Dianne G. Woodhouse, Frederick A. O. Mendelsohn, George Paxinos
Publikováno v:
The Journal of comparative neurology. 304(3)
Because of the importance of the catecholamine system in Parkinson's disease and its relevance to a variety of clinical movement disorders, catecholamine uptake sites were mapped in the human brain using [3H] mazindol autoradiography. Displacement st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1d454b54ba7d0187ab674fcba8beeb
https://pubmed.ncbi.nlm.nih.gov/2022757
https://pubmed.ncbi.nlm.nih.gov/2022757
Publikováno v:
Journal of the Neurological Sciences. 77:185-191
Motor function was assessed by use of a swim test in C57 Black mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Thirty minutes after the last MPTP injection significant motor impairment was observed while striatal dopamine was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631cdf10f06f20722ffd14f91280af88
https://doi.org/10.1016/0022-510x(87)90121-3
https://doi.org/10.1016/0022-510x(87)90121-3