Zobrazeno 1 - 10
of 74
pro vyhledávání: '"S.G Gilbey"'
Publikováno v:
Journal of Human Nutrition and Dietetics. 6:457-460
A patient with a pancreatic tumour suffered severe diarrhoea as a result of abnormal secretions of vasoactive intestinal polypeptide. Initial elemental feeding and continued nutritional support improved her nutritional status. The patient currently s
Publikováno v:
Experimental Physiology. 78:697-705
The effects of modification of the levels of endogenous plasma insulin on intestinal epithelial cell proliferation were investigated in rats maintained by total parenteral nutrition (TPN) using either a TPN diet that was high in glucose, or a low glu
Autor:
C. Bohuon, A.A.M. Al-Dokhayel, E. Comoy, P.D. Lambert, S.G. Gilbey, Stephen R. Bloom, John P.H. Wilding
Publikováno v:
Endocrinology. 133:29-32
A marked increase in food intake is observed in the rat after central injection of neuropeptide-Y (NPY), dynorphin, or noradrenaline (NA). Levels of both NPY and dynorphin are increased in the hypothalamus of food-deprived rats. The aim of this study
Publikováno v:
Peptides. 13:557-563
Neuropeptide Y (NPY) is a powerful appetite stimulant, and hypothalamic concentrations rise after food deprivation and in experimental diabetes. Serotonergic drugs such as dexfenfluramine are inhibitors of feeding. We measured hyothalamic NPY and NPY
Publikováno v:
Journal of Endocrinology. 132:299-304
Neuropeptide Y (NPY) is the most powerful appetite stimulant known, and chronic administration leads to obesity. The hypothalamic content of NPY varies with nutritional status, suggesting that it is of physiological importance. We measured NPY in spe
Publikováno v:
Diabetologia. 33:115-117
The presence of islet amyloid polypeptide in amyloid within pancreatic islet cells in Type 2 (non-insulin-dependent) diabetes, and its reported inhibition of glucose uptake by skeletal muscle in vitro, has prompted speculation concerning its role in
Autor:
J. Beacham, N. Khandan-Nia, W. M. Bennet, S.G. Gilbey, M. A. Ghatei, S.R. Bloom, John P.H. Wilding
Publikováno v:
Diabetologia. 37(2)
It is suggested that amylin (islet associated polypeptide), co-secreted with insulin from the pancreatic beta cells acts as a circulating hormone which opposes the action of insulin on muscle and increases hepatic glucose production. We have tested t
Autor:
Simon C. Wallis, Graham F. Joplln, S.G. Gilbey, Markus Bettendorf, Judith E. Allanson, Eric Rhéaume, Fernand Labrie, J Simard, Udo Heinrich, Jean-François Lebianc, Gabrielle Mettler
Publikováno v:
Human molecular genetics. 3(2)
Classical 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) deficiency is an autosomal recessive form of congenital adrenal hyperplasia caused by mutations in the type II 3 beta-HSD (HSD3B2) gene. The sequence of the type II 3 beta-HSD gene was determ
Publikováno v:
Peptides. 15(4)
We measured neuropeptide Y (NPY) concentration in microdissected hypothalamic nuclei, by radioimmunoassay, and NPY mRNA in the hypothalamus in rats treated systemically with the nonspecific opioid antagonist, naloxone, to produce mild anorexia. Twent
Publikováno v:
Brain research. 629(1)
Neuropeptide Y (NPY) and the endogenous kappa-opioid receptor ligand, dynorphin (dyn), stimulate feeding when injected centrally in the rat. Norbinaltorphimine (norBNI, 25 nmol) reduced the feeding response to NPY (2.4 nmol) by 67% (P < 0.02). An add