Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S.Edward Lee"'
Autor:
Steven J. Hawrylik, Frank S. Kaczmarek, S.Edward Lee, Kieran F. Geoghegan, Dennis E. Danley, Robert D. Gerard, Arthur Ernest Franke
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1037:16-23
Expression of human recombinant plasminogen activator inhibitor type-1 (PAI-1) in Escherichia coli has led to crystallization of 'latent' PAI-1. Cleavage with restriction endonucleases of a cDNA clone encoding PAI-1 yielded an 1127 base pair fragment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c477cf52a2c76c0a6f5a9e5e546b064
https://doi.org/10.1016/0167-4838(90)90096-x
https://doi.org/10.1016/0167-4838(90)90096-x
Autor:
S.Edward Lee, Peter John Whittle, Stephen Hawrylik, Andrew M. Hemmings, James Merson, James E. Pitts, John P. Overington, Kathryn Shield, Andrew F. Wilderspin, S. P. Wood, Kieran Francis Geoghegan, Laurence H. Pearl, R. Lapatto, Peter M. Hobart, Tom L. Blundell, Dennis Edward Danley, Duncan J. H. Gaskin, Zhang-Yang Zhu
Publikováno v:
Retroviral Proteases ISBN: 9780333536124
HIV-1 proteinase processes its virally encoded polyproteins into mature structural proteins and enzymes that are essential for viral propagation. As a consequence the proteinase is an attractive target for prospective antiviral agents for the treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344cecd549e9dbb42146cbca1fdbf640
https://doi.org/10.1007/978-1-349-11907-3_10
https://doi.org/10.1007/978-1-349-11907-3_10
Autor:
S.Edward Lee, Graham Rickett, Dennis E. Danley, Mark Ammirati, Kathryn G. Scheld, Peter M. Hobart, James R. Merson, Kieran F. Geoghegan, Steven J. Hawrylik
Publikováno v:
Biochemical and Biophysical Research Communications. 165:1043-1050
A plasmid vector was used to express the HIV-1 pol open reading frame under the regulation of the bacterial trp promoter in Escherichia coli. This expression system has been used as a source of recombinant viral protease. The self-processed active en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35cb6e13bf0dbafd5b462b83fa0572c3
https://doi.org/10.1016/0006-291x(89)92707-1
https://doi.org/10.1016/0006-291x(89)92707-1