Zobrazeno 1 - 10
of 14
pro vyhledávání: '"S.E.M., standard error of the mean"'
Autor:
Zhenyi Li, Yali Wang, Sanya Ahmed, Martin Vreugdenhil, Yujiao Zhang, Jianbin Wen, Georgiana Neagu, Chunjie Liu
Publikováno v:
IBRO Reports
IBRO Reports, Vol 6, Iss, Pp 122-131 (2019)
IBRO Reports, Vol 6, Iss, Pp 122-131 (2019)
Highlights • CA3 gamma oscillation (γ) drives CA1 gamma and suppresses CA1 intrinsic fast γ. • μ-opioid receptor (MOR) activation reduces γ frequency in CA3 and CA1. • MOR activation in CA1 phase-uncouples CA1 γ from CA3 γ. • Uncoupling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8867c275a463eabf2fe3c82f772d7b
https://doi.org/10.1016/j.ibror.2019.01.004
https://doi.org/10.1016/j.ibror.2019.01.004
Autor:
Fiona Randall, Peter Atkinson, Fiona E. N. LeBeau, Christopheer M. Morris, Joshua Curry, Clare Tweedy, John-Paul Taylor, Gavin J. Clowry, Daniel Erskine, Amy K. Reeve, Nathan Kindred, Christopher M. Williams
Publikováno v:
Neurobiology of Disease, Vol 149, Iss, Pp 105226-(2021)
Neurobiology of Disease
Neurobiology of Disease
Abnormal excitability in cortical networks has been reported in patients and animal models of Alzheimer's disease (AD), and other neurodegenerative conditions. Whether hyperexcitability is a core feature of alpha(α)-synucleinopathies, including deme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e332102b731825f1f488e183205ac8d9
http://www.sciencedirect.com/science/article/pii/S0969996120305015
http://www.sciencedirect.com/science/article/pii/S0969996120305015
Autor:
Paulo Vitor Moreira Romão, Arquimedes Gasparotto Junior, Denise Brentan Silva, Samara Requena Nocchi, Emerson Luiz Botelho Lourenço, Carlos Calixto dos Santos, Francielly Mourão Gasparotto, Lucas Pires Guarnier, Rhanany Alan Calloi Palozi
Publikováno v:
Toxicology Reports, Vol 6, Iss, Pp 616-624 (2019)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Fruit peels of Plinia cauliflora are widely used in Brazilian traditional medicine. • No studies have proved the safety of its pharmacological effects. • We assessed the safety pharmacology of P. cauliflora
Highlights • Fruit peels of Plinia cauliflora are widely used in Brazilian traditional medicine. • No studies have proved the safety of its pharmacological effects. • We assessed the safety pharmacology of P. cauliflora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fe7a8a0d2bb4952c84b778a8998ce6
https://doi.org/10.1016/j.toxrep.2019.06.017
https://doi.org/10.1016/j.toxrep.2019.06.017
Publikováno v:
The Journal of Biological Chemistry
N-myc-downregulated gene 1 (NDRG1) has potent anti-cancer effects and inhibits cell growth, survival, metastasis, and angiogenesis. Previous studies suggested that NDRG1 is linked to the androgen signaling network, but this mechanistic relationship i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e33581f9dbfbe17c615d55e5392ba6
https://doi.org/10.1016/j.jbc.2021.101414
https://doi.org/10.1016/j.jbc.2021.101414
Publikováno v:
Biochemistry and Biophysics Reports
Human dihydrolipoamide dehydrogenase (hLADH) is a flavoenzyme component (E3) of the human alpha-ketoglutarate dehydrogenase complex (α-KGDHc) and few other dehydrogenase complexes. Pathogenic mutations of hLADH cause severe metabolic diseases (atypi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f253023b9ddcae20aeeaf051add560
https://doi.org/10.1016/j.bbrep.2015.04.006
https://doi.org/10.1016/j.bbrep.2015.04.006
Publikováno v:
European Journal of Pharmacology
Neural precursor cell expressed, developmentally down-regulated protein 4-2 (Nedd4-2) mediates the internalisation / degradation of epithelial Na(+) channel subunits (α-, β- and γ-ENaC). Serum / glucocorticoid inducible kinase 1 (SGK1) and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0731548af26982499e50f69251c7c97
https://pubmed.ncbi.nlm.nih.gov/24657276
https://pubmed.ncbi.nlm.nih.gov/24657276
Autor:
Tracey L. Purvis, Karen Piper Hanley, Neil A. Hanley, Tom Hearn, Cosma Spalluto, David I. Wilson, Victoria J. Knorz, Tilman Sanchez-Elsner
Publikováno v:
Gene
Mutations in the human gene ALMS1 cause Alström syndrome, a disorder characterised by neurosensory degeneration, metabolic defects and cardiomyopathy. ALMS1 encodes a centrosomal protein implicated in the assembly and maintenance of primary cilia. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7364927d2dc392987d5275b8098eb4
Autor:
A. de Vries, Graham A. W. Rook, Andrea Evans, Jacob Harvey Hollis, Jon R. F. Hunt, Julian F. R. Paton, E. van Kampen, B. Pan, Christopher A. Lowry, Stafford L. Lightman, DM Knight, Laura Rosa Brunet
Publikováno v:
Neuroscience
Peripheral immune activation can have profound physiological and behavioral effects including induction of fever and sickness behavior. One mechanism through which immune activation or immunomodulation may affect physiology and behavior is via action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0deba7ba4eddc6a3d2ee77d651fb8bd
Publikováno v:
Neuroscience
Cortical sensory neurons adapt their response properties to use and disuse of peripheral receptors in their receptive field. Changes in synaptic strength can be generated in cortex by simply altering the balance of input activity, so that a persisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed07682244c8db5403df11d376d6bcd
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