Zobrazeno 1 - 10
of 20
pro vyhledávání: '"S.E. Porteus"'
Publikováno v:
Prostaglandins. 18:377-385
Intravenous injection of 600 μg PGE 2 or PGI 2 significantly increased serum LH and prolactin levels in estradiol treated ovariectomized rats. There was no effect on serum FSH concentration. PGE 2 and PGI 2 stimulated LH release in a non-dose depend
Autor:
P. V. Malven, S.E. Porteus
Publikováno v:
Endocrinology. 94:1699-1703
Hypophysectomized female rats which had received renal grafts of anterior pituitary (AP) were sampled by heart puncture under pentobarbital (PB) anesthesia. Serum prolactin in sequential samples from each rat was measured by radioim-munoassay to dete
Autor:
N.R. Mohberg, S.E. Porteus, John W. Wilks, F.A. Kimball, Robert D. Frielink, A.D. Forbes, L.F. Turner, K.T. Kirton
Publikováno v:
Prostaglandins. 18:117-126
Adult male rhesus were treated with PGE2, PGF2 alpha or the 13,14-dihydro-15-keto metabolite of PGE2 in a randomized crossover design. Serum concentrations of FSH, LH and testosterone were determined and compared to the respective values in the same
Publikováno v:
Contraception. 11:91-104
Experimental data in the rat is presented for an approach to male fertility regulation. The concept involves administration of an anti-gonadotropic steroid plus a replacement androgen to inhibit spermatogenesis and to maintain normal secondary sex ch
Autor:
S.E. Porteus, T.J. Lobl
Publikováno v:
Contraception. 17(2)
5-Thio-D-glucose given orally to mice at 50 mg/kg/day for up to 49 days inhibited spermatogenesis and fertility, confirming an earlier report. Contrary to the earlier report, the antispermatogenic activity and the drug-induced infertility were only p
Publikováno v:
Fertility and sterility. 29(1)
Silicone rubber discs containing 15(S)-15-methyl prostaglandin F2 alpha ester (15-Me-PGF2 alpha) in the matrix were implanted in the left side of the scrotums of Sprague-Dawley rats. The effect of 1% and 2% drug concentration was examined for 10, 20,
Autor:
S.E. Porteus, F.A. Kimball
Publikováno v:
Prostaglandins. 16(3)
Pregnant hamsters were administered (SC) prostaglandin or vehicle on the morning of the 4th day of pregnancy. Serum progesterone was significantly depressed (p less than .01) at 0.5, 2, and 6 hours after treatment with 100 microgram PGF2alpha. Serum
Publikováno v:
Fertility and sterility. 29(1)
Male Spraque-Dawley rats receiving implants of silicone rubber discs containing 1% or 2% 15(S)-15-methyl prostaglandin F2 alpha methyl ester (15-Me-PGF 2 alpha) or no prostaglandin were tested in successive breeding trials for potency and fertility.
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