Zobrazeno 1 - 10
of 137
pro vyhledávání: '"S.E. Gandy"'
Autor:
S.E. Gandy, B.K. Reilly
Publikováno v:
Koedoe: African Protected Area Conservation and Science, Vol 47, Iss 1, Pp 119-124 (2004)
The African buffalo is considered the classic African trophy. It is the choice of many hunters who will never go on to hunt any of the other dangerous game animals on the continent. A good trophy is perceived as that of a mature bull with a hardened
Externí odkaz:
https://doaj.org/article/762a53716e334712b9390f5c0b0d8ebb
Akademický článek
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Akademický článek
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Autor:
Eugene Hone, Brian Dean, Catriona McClean, Ralph N. Martins, Elizabeth A. Thomas, Nicola T. Lautenschlager, Simon M. Laws, S.E. Gandy, Elizabeth Scarr, Kevin Taddei, Clive Harper, Colin L. Masters
Publikováno v:
Biological Psychiatry. 54:616-622
Background It is unclear whether altered expression of a specific isoform of apolipoprotein E (apoE) is associated with the pathology of schizophrenia. Methods To address whether apoE may be involved in the pathology of schizophrenia, we measured the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8345042c6175c3be3bb18213239fdd6
https://doi.org/10.1016/s0006-3223(03)00075-1
https://doi.org/10.1016/s0006-3223(03)00075-1
Akademický článek
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Autor:
Paul Greengard, Rong Wang, Gunnar K. Gouras, Norman R. Relkin, Jasmina N. Jovanovic, Joseph D. Buxbaum, Huaxi Xu, S.E. Gandy
Publikováno v:
Europe PubMed Central
Studies of processing of the Alzheimer beta-amyloid precursor protein (betaAPP) have been performed to date mostly in continuous cell lines and indicate the existence of two principal metabolic pathways: the "beta-secretase" pathway, which generates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb613ba08ca7521cc581e03c6a3d76e6
https://doi.org/10.1046/j.1471-4159.1998.71051920.x
https://doi.org/10.1046/j.1471-4159.1998.71051920.x
Autor:
Roger Clarnette, Christopher M. Fisher, S.E. Gandy, P. St. George-Hyslop, C. Chung, Athena Paton, Georgia Martins, Simon M. Laws, Ralph N. Martins, Kevin Taddei, Judith Miklossy, William S. Brooks, Norman R. Relkin, Joachim Hallmayer
Publikováno v:
Molecular Psychiatry. 7:776-781
Mutations in the presenilin-1 (PS-1) gene on chromosome 14 account for the majority of early-onset familial Alzheimer's disease (FAD) cases. To date, more than 90 mutations have been identified and, while most of these mutations are completely penetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601fd17e57bc29a7e69f7523739ceac8
https://doi.org/10.1038/sj.mp.4001072
https://doi.org/10.1038/sj.mp.4001072
Autor:
Paul M. Mathews, Dun-Sheng Yang, Shigeki Arawaka, Gang Yu, Triprayer V. Ramabhadran, S.E. Gandy, Stephen D. Schmidt, Peter St George-Hyslop, Monika Duthie, Paul E. Fraser, Fusheng Chen, Ralph A. Nixon, Hiroshi Hasegawa, Howard T.J. Mount, Anurag Tandon, Haung Yu
Publikováno v:
Journal of Biological Chemistry. 277:28135-28142
Nicastrin is an integral component of the high molecular weight presenilin complexes that control proteolytic processing of the amyloid precursor protein and Notch. We report here that nicastrin is most probably a type 1 transmembrane glycoprotein th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cd193b8ad7ce48802350f343b9c818
https://doi.org/10.1074/jbc.m110871200
https://doi.org/10.1074/jbc.m110871200
Autor:
S.E. Gandy, Suzana Petanceska
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502(1):44-52
Alzheimer’s disease (AD) is characterized by the intracranial accumulation of the 4 kDa amyloid-β peptide (Aβ), following proteolysis of a ∼700-amino acid, integral membrane precursor, the Alzheimer amyloid precursor protein (APP). The best evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc741e06bc82c8e69ae146a4f346adfd
Autor:
Kevin Taddei, Ralph N. Martins, Joachim Hallmayer, Adam Boyt, Suzanne Craft, S.E. Gandy, Erik Helmerhorst
Publikováno v:
Neuroscience. 95:727-734
The deposition of beta amyloid is a critical event in the pathogenesis of Alzheimer's disease. This peptide is a metabolite of the amyloid precursor protein. Recent research suggests that there is a correlation between plasma insulin and glucose conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f5f0e68fb50eb5e923d1f4895c6f91
https://doi.org/10.1016/s0306-4522(99)00458-3
https://doi.org/10.1016/s0306-4522(99)00458-3