Zobrazeno 1 - 10
of 50
pro vyhledávání: '"S.E. Bursell"'
Autor:
S.E. Bursell, N. Horio, T. Abiko, A. Abiko, B. D. Shoelson, Allen C. Clermont, Edward P. Feener
Publikováno v:
Diabetologia. 47:113-123
The renin angiotensin system is emerging as a potential therapeutic target for diabetic retinopathy. This study examines the effects of angiotensin-converting-enzyme inhibition by captopril and angiotensin AT(1) receptor antagonism using candesartan-
Autor:
Allen C. Clermont, Lloyd Paul Aiello, Fumio Umeda, Eric A. Pierce, Teruaki Yamauchi, Izumi Suzuma, Tatsuro Ishibashi, Yasuaki Hata, Hiroyuki Kagokawa, S.E. Bursell, Gregory S. Robinson, Hiroshi Yoshikawa, Toshihiko Hashimoto
Publikováno v:
Journal of Clinical Investigation. 106:541-550
Prostacyclin-stimulating factor (PSF) acts on vascular endothelial cells to stimulate the synthesis of the vasodilatory molecule prostacyclin (PGI2). We have examined the expression, regulation, and hemodynamic bioactivity of PSF both in whole retina
Autor:
S.E. Bursell, George L. King, Toyoshi Inoguchi, Teruo Shiba, William F. Heath, J. R. Sportsman
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 265:E783-E793
The increases in diacylglycerol (DAG) level and protein kinase C (PKC) activity have been characterized biochemically and functionally in the retina and the brain of diabetic rats as well as in cultured vascular cells. PKC specific activities were in
Autor:
Shyamali Ghosh, Bart L. DeCorte, Tuman Robert W, S.E. Bursell, William A. Kinney, Alan C. Clermont, Li Liu, Rosemary J. Santulli, Robert A. Galemmo, Norman Huebert, Lynn C. Shaw, Shaker A. Mousa, Dana L. Johnson, Bruce E. Maryanoff, Bruce P. Damiano, Zhao Zhou, Maria B. Grant
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 324(3)
The alpha(V) integrins are key receptors involved in mediating cell migration and angiogenesis. In age-related macular degeneration (AMD) and diabetic retinopathy, angiogenesis plays a critical role in the loss of vision. These ocular vasculopathies
Autor:
S.E. Bursell, Jun S Wong, Allen C. Clermont, Haytham I. Salti, D. Bursell, Mark T Cahill, Lloyd Paul Aiello, Susan L. Rook, LE Goddard, Christian Rask-Madsen
Publikováno v:
Investigative ophthalmologyvisual science. 47(6)
PURPOSE. Although vascular endothelial growth factor (VEGF) is a key mediator of retinal vascular permeability (RVP), there may be additional humoral contributors. Hepatocyte growth factor (HGF) induces endothelial cell separation, regulates expressi
Autor:
Vivek J. Srinivasan, James G. Fujimoto, Maciej Wojtkowski, Allen C. Clermont, Jay S. Duker, S.E. Bursell, Tony H. Ko
Publikováno v:
SPIE Proceedings.
Non-invasive in vivo functional optical imaging is emonstrated using high-speed, ultrahigh resolution optical coherence tomography (UHR-OCT). A high-speed, UHR-OCT system using spectral/Fourier domain detection was developed for functional imaging ex
Autor:
Robert A. Vigersky, Mary G. Lawrence, Ned Hope, Ingrid Zimmer-Galler, Lisa J. Carnahan, Jerry D. Cavallerano, Wendall Bauman, Mark B. Horton, Gary Buck, Thomas P. Ward, John M. Peters, Ying-Ling Chen, Bernard Szirth, Jay L. Federman, Peter Soliz, Peter M. Kuzmak, Lloyd Paul Aiello, W. Kelly Gardner, Denise Cunningham, Lloyd M. Aiello, Eric Goodall, S.E. Bursell, Diane Parker-Taillon, Jonathan D. Linkous, Richard Bakalar, Robert Read, Eugene Huang, Jehanara Ahmed, Ronald K. Poropatich, Jordana Motzno, Matthew T.S. Tennant, Lloyd Hildebrand, Hiro Matsuzaki, Helen K. Li, Catherine Diver, Adam Darkins, James W. L. Lewis, Mark Janczewski, Larry D. Hubbard, Francis L. McVeigh
Publikováno v:
Telemedicine journal and e-health : the official journal of the American Telemedicine Association. 10(4)
Telehealth holds the promise of increased adherence to evidenced-based medicine and improved consistency of care. Goals for an ocular telehealth program include preserving vision, reducing vision loss, and providing better access to medicine. Establi
Autor:
David Vicent, George L. King, Jacob Ilany, S.E. Bursell, Yaz Y. Kisanuki, Tatsuya Kondo, Keiko Naruse, C. Ronald Kahn, Simon J. Fisher, Masashi Yanagisawa
Publikováno v:
The Journal of clinical investigation. 111(9)
Insulin receptors (IRs) on vascular endothelial cells have been suggested to participate in insulin-regulated glucose homeostasis. To directly address the role of insulin action in endothelial function, we have generated a vascular endothelial cell I
Autor:
James G. Fujimoto, Uwe Morgner, Ravi K. Ghanta, S.E. Bursell, Erich P. Ippen, Wolfgang Drexler, Joel S. Schuman, Franz X. Kärtner
Publikováno v:
New York University Scholars
In vivo ultrahigh resolution, spectroscopic optical coherence tomography (OCT) with 3µm axial resolution allows for an unprecedented visualization of microstructure relevant to pathology in the anterior eye and retina. The visualization of retinal m
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