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Interaction of N-acetylcysteine with DPPC liposomes at different pH: a physicochemical study

Autor: Juan Marcelo Arias, Aida Ben Altabef, S.B. Díaz, M.E. Tuttolomondo, Rafael Alejandro Cobos Picot

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

The N-acetylcysteine (NAC) is a commonly used mucolytic and antioxidant agent. The knowledgeof interactions of the NAC with cell membranes is important to understand its mechanism ofpharmacological action at the molecular level. To gain a deeper insi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa299fde773b65452e44142f16d5743
https://doi.org/10.1039/c9nj06167c

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Interaction of cysteine and its derivatives with monolayers of dipalmitoylphosphatidylcholine

Autor: Fernando Gabriel Dupuy, A. Ben Altabef, S.B. Díaz, Juan Marcelo Arias

Molecular interactions between l-cysteine (Cys) and its ester derivatives (Cysx); l-cysteine ethyl ester (CE), l-cysteine methyl ester (CM) and N-acetyl l-cysteine (NAC) with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) monolayers were investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6f22ac5f85236de7bc361e31619fa75
https://www.sciencedirect.com/science/article/abs/pii/S0927776519306927

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Structural and vibrational characterization of anhydrous and dihydrated species of trehalose based on the FTIR and FTRaman spectra and DFT calculations

Autor: Silvia Antonia Brandán, S.B. Díaz, María Jimena Márquez, Davide Romani

Publikováno v: Journal of King Saud University: Science, Vol 30, Iss 2, Pp 229-249 (2018)

In this study, three anhydrous species of trehalose and their dihydrated form were studied using the Fourier Transform Infrared (FTIR) and Raman spectroscopy combined with theoretical calculations derived from the theory of the functional of the dens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f666887dff41a18052dcf784dc4875c
http://www.sciencedirect.com/science/article/pii/S1018364716306413

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Molecular view of the structural reorganization of water in DPPC multilamellar membranes induced by l -cysteine methyl ester

Autor: Aida Ben Altabef, M.E. Tuttolomondo, S.B. Díaz, Juan Marcelo Arias

Publikováno v: Journal of Molecular Structure. 1156:360-368

In order to study the interaction between L-cysteine methyl ester (CM) and multilamellar vesicles (MLV's) of DPPC, an extensive study was made by various techniques such as Infrared and Raman spectroscopy and Differential Scanning Calorimetry (DSC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1df894625791f10cfdf50bd05fc7f39
https://doi.org/10.1016/j.molstruc.2017.11.124

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Characterization of interactions of eggPC lipid structures with different biomolecules

Autor: F. Corrales Chahar, Claudio A. Gervasi, S.B. Díaz, P. E. Álvarez, A. Ben Altabef

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

In this paper we study the interactions of two biomolecules (ascorbic acid and Annonacin) with a bilayer lipid membrane. Egg yolk phosphatidylcholine (eggPC) liposomes (in crystalline liquid state) were prepared in solutions of ascorbic acid (AA) at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00834b1f28bf1e8cd0d2d00bc99d09a
https://doi.org/10.1016/j.chemphyslip.2017.11.013

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Akademický článek

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Interactions of valproic acid with lipid membranes of 1,2-dimyristoyl-sn-glycero-3-phosphocholine

Autor: P. E. Álvarez, Claudio A. Gervasi, F. Corrales Chahar, A. Ben Altabef, S.B. Díaz

Publikováno v: Chemistry and physics of lipids. 218

Lipid bilayers of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) were prepared in two forms, as a suspension of multilamellar spherical vesicles and as planar membranes deposited on a conductive solid support. We used Fourier Transformed Infrared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993bfaf53b61a24c65663e57a7d82673
https://pubmed.ncbi.nlm.nih.gov/30582895

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Reorganization of Hydration Water of DPPC Multilamellar Vesicles Induced by l-Cysteine Interaction

Autor: Aida Ben Altabef, Juan Marcelo Arias, M.E. Tuttolomondo, S.B. Díaz

Publikováno v: The journal of physical chemistry. B. 122(20)

The aim of this study is to analyze the consequences of water redistribution on the structure and stability of phospholipid bilayers induced by cysteine (Cys). This interaction is studied with 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ec1ca7b2874150b58d455bf7e10fd4
https://pubmed.ncbi.nlm.nih.gov/29717612

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FTIR and Raman analysis ofl-cysteine ethyl ester HCl interaction with dipalmitoylphosphatidylcholine in anhydrous and hydrated states

Autor: S.B. Díaz, Juan Marcelo Arias, M.E. Tuttolomondo, Aida Ben Altabef

Publikováno v: Journal of Raman Spectroscopy. 46:369-376

Interactions of l-cysteine ethyl ester hydrochloride (CE), a bioactive cysteine derivative, with dipalmitoylphosphatidylcholine (DPPC) were investigated. To gain a deeper insight into analyzing l-cysteine ethyl ester HCl interaction with liposomes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e9f012e9447418e82105ef8ea42a88f
https://doi.org/10.1002/jrs.4659

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