Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases

Autor: Ewa Ninio, J.W. Jukema, Erna Peters, James R. Mitchell, S.A.P. Karabina, Johan Frostegård, R.C.M. Jong, A. Bergman, Margreet R. de Vries, I. Dahlbom, Michael R MacArthur, M.M. Ewing, M. Nordzell, D.J. Sexton, J.C. Karper, Paul H.A. Quax, Knut Pettersson, J. Kuiper

Publikováno v: Journal of Internal Medicine, 290 (1)
Journal of Internal Medicine, 290(1), 141-156. WILEY
Journal of Internal Medicine
Journal of Internal Medicine, Wiley, 2020, ⟨10.1111/joim.13234⟩

Background Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated molecular pattern. Previous data have shown that natural IgM anti‐PC protects against cardiovascular disease. We aimed to develop a monoclonal PC IgG antibody

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63977bd8d6d72a00632bfb05a3ee8956
https://hdl.handle.net/20.500.11850/465611

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