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Primary prophylaxis of variceal bleeding in cirrhotics unable to take beta-blockers: a randomized trial of ligation

Autor: G. Leandro, A. Armonis, Jiannis Vlachogiannakos, Alec Avgerinos, Spilios Manolakopoulos, AK Burroughs, A. Kougioumtzian, A. Saveriadis, S.A. Raptis, Christos Triantos, Dimitrios Tzourmakliotis

Publikováno v: Alimentary Pharmacology and Therapeutics. 21:1435-1443

Summary Aim : To compare endoscopic banding ligation vs. no treatment in cirrhotics with intolerance or contraindications to β-blockers for prevention of first bleeding in portal hypertension. Methods : A sample size of 214 was planned with all size

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23953ec19d6173e7d90f88aced60a44f
https://doi.org/10.1111/j.1365-2036.2005.02457.x

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Pulsatile human corticotropin-releasing hormone prevents dexamethasone-induced suppression of the plasma cortisol response to hypoglycemia in normal men

Autor: P C Avgerinos, C K Kiamouris, I K Kleanthous, I P Petrakos, T N Dimitriadis, S.A. Raptis, P A Zorzos, G B Cutler

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 75:1358-1361

Insulin-induced hypoglycemia causes a sequential stimulation of all three components of the hypothalamic-pituitary-adrenal axis. States of acute glucocorticoid excess, such as the overnight (1 mg) dexamethasone suppression test (DST), inhibit both th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24af88093acb5e3a2e4e6cc3e7080342
https://doi.org/10.1210/jcem.75.5.1331166

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The effect of an eucaloric high carbohydrate diet on circulating levels of glucose, fructose and non-esterified fatty acids in patients with cirrhosis

Autor: Alec Avgerinos, Stavros Bousboulas, D. S. Harry, Vasiliki Komesidou, S.A. Raptis, Evangelia Theodossiadou, Neil McIntyre, Athina Pallikari

Publikováno v: Journal of Hepatology. 14:78-87

Twelve cirrhotic patients and six controls were fed an eucaloric high carbohydrate (CHO) diet for 3 days. Fasting serum triglyceride (TG), non-esterified fatty acids (NEFA), glucose, insulin and glycerol were estimated daily. On the 3rd day of the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2315b3947d1a484a4b7a2ab2fdff0afb
https://doi.org/10.1016/0168-8278(92)90134-b

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TNF-alpha, TGF-beta1, IL-10, IL-6, gene polymorphisms in latent autoimmune diabetes of adults (LADA) and type 2 diabetes mellitus

Autor: Anastasia Tsiavou, A. Chaidaroglou, K. Koniavitou, A. Manginas, Erifili Hatziagelaki, D. Degiannis, S.A. Raptis

Publikováno v: Journal of clinical immunology. 24(6)

Abundant evidence suggests that cytokines involve in the pathogenesis of latent autoimmune diabetes of adults (LADA). This is a slowly progressive form of type 1 diabetes, which is initially diagnosed as type 2 diabetes. In this study, healthy indivi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22af594526cc8cdc102b2e345ed8d16
https://pubmed.ncbi.nlm.nih.gov/15622443

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Correlation between intracellular interferon-gamma (IFN-gamma) production by CD4+ and CD8+ lymphocytes and IFN-gamma gene polymorphism in patients with type 2 diabetes mellitus and latent autoimmune diabetes of adults (LADA)

Autor: Antigoni Chaidaroglou, Erifili Hatziagelaki, S.A. Raptis, K. Koniavitou, Anastasia Tsiavou, D. Degiannis

Publikováno v: Cytokine. 31(2)

IFN-gamma is considered to be involved in the pathogenesis of diabetes mellitus. In this study, the presence of T/A mutation at position -874 in IFN-gamma gene was assessed in patients with latent autoimmune diabetes of adults (LADA), in patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3175d779f7648cc2fecb6e79772dc3ec
https://pubmed.ncbi.nlm.nih.gov/15935691

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Intracellular IFN-gamma production and IL-12 serum levels in latent autoimmune diabetes of adults (LADA) and in type 2 diabetes

Autor: D. Degiannis, K. Koniavitou, Erifili Hatziagelaki, S.A. Raptis, Anastasia Tsiavou

Publikováno v: Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 24(7)

Th1 cytokines, such as interleukin-2 (IL-2) and interferon-gamma (IFN-gamma), and Th1-inducing cytokines, such as IL-12, are involved in the pathogenesis of various organ-specific autoimmune diseases, including autoimmune diabetes. In this study, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8490d2295b4aa85afcc66f401b3814b
https://pubmed.ncbi.nlm.nih.gov/15296648

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Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants

Autor: Anastasia Tsiavou, Erifili Hatziagelaki, S.A. Raptis, K. Koniavitou, D. Degiannis

Publikováno v: International immunopharmacology. 2(12)

Interleukin 12 (IL-12) is a potent regulator of the Th1/Th2 pathway, enhancing alloantigen-specific immune functions. In the present study, we developed a flow cytometric assay detecting intracellular IL-12 production by human CD14+ monocytes in orde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd7db5f260a1bb2a5bd5fc1ba50ab4d
https://pubmed.ncbi.nlm.nih.gov/12469945

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