Zobrazeno 1 - 10
of 35
pro vyhledávání: '"S.A. Neale"'
Publikováno v:
British Journal of Pharmacology. 179:1607-1619
BACKGROUND AND PURPOSE As the thalamus underpins almost all aspects of behaviour, it is important to understand how the thalamus operates. Group II metabotropic glutamate (mGlu2 /mGlu3 ) receptor activation reduces inhibition in thalamic nuclei origi
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Autor:
Korrapati V. Sathyasaikumar, Robert Schwarcz, S.A. Neale, Margarita A. Tararina, Hui-Qiu Wu, F. Weisz, Thomas E. Salt
Publikováno v:
Neuroscience. 367
Xanthurenic acid (XA), formed from 3-hydroxykynurenine (3-HK) in the kynurenine pathway of tryptophan degradation, may modulate glutamatergic neurotransmission by inhibiting the vesicular glutamate transporter and/or activating Group II metabotropic
Publikováno v:
The Journal of Physiology. 590:937-951
Group II metabotropic glutamate receptor (mGlu) modulation of sensory processing in the rat ventrobasal thalamic nucleus (VB) has been extensively studied in vivo. However, it is not yet known what the relative contributions are of the Group II mGlu
Akademický článek
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Autor:
Thomas E. Salt, S.A. Neale
Publikováno v:
The Journal of Physiology. 577:659-669
Previous work has indicated that metabotropic glutamate receptors (mGluRs) modulate visual responses of superior colliculus (SC) neurones in vivo in a variety of ways, in a manner that can be dependent upon visual stimulus properties. How this occurs
Publikováno v:
Neuropharmacology. 47:822-832
Previous work from this laboratory indicates that Group II/III metabotropic glutamate (mGlu) receptors modulate responses of SC neurones to visual stimuli in vivo. It is thought that tonic levels of glutamate may be sufficient to activate some mGlu r
Publikováno v:
Molecular Pharmacology. 61:97-104
In the rat isolated optic nerve, nitric oxide (NO) activates soluble guanylyl cyclase (sGC), resulting in a selective accumulation of cGMP in the axons. The axons are also selectively vulnerable to NO toxicity. The experiments initially aimed to dete
Publikováno v:
European Journal of Neuroscience. 14:1313-1319
Metabotropic glutamate (mGlu) receptors are located pre- and postsynaptically at central synapses. Activation of the receptors by exogenous agonists usually results in a reversible depression of fast glutamatergic neurotransmission. Evidence that syn
Publikováno v:
Neuropharmacology. 41:42-49
The actions of reportedly group-selective metabotropic glutamate (mGlu) receptor agonists and antagonists on neurotransmission at parallel fibre-Purkinje cell synapses in the rat cerebellum have been characterised using sharp microelectrode recording