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Consequences of Metabolic Disruption in Alzheimer’s Disease Pathology

Autor: Pedro Rosa-Neto, S. O. Yoon, J. C. Ryu, Eduardo R. Zimmer

Publikováno v: Neurotherapeutics

Alzheimer’s disease (AD) is an irreversible, progressive disease that slowly destroys cognitive function, such as thinking, remembering, and reasoning, to a level that one cannot carry out a daily living. As people live longer, the risk of developi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f084c1782e9019530d5c8c243b87c68c
https://europepmc.org/articles/PMC6694332/

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Akademický článek

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LAB-ANGIOGENESIS AND INVASION

Autor: M. A. Proescholdt, M. J. Merrill, E.-M. Stoerr, A. Lohmeier, A. Brawanski, H. Sim, B. Hu, C. A. Pineda, S.-O. Yoon, M. S. Viapiano, P. Rajappa, W. S. Cobb, Y. Huang, D. C. Lyden, J. Bromberg, J. P. Greenfield, M. Li, A. Mukasa, M. d.-M. Inda, J. Zhang, L. Chin, W. Cavenee, F. Furnari, P.-P. Zheng, M. van der Weiden, P. J. van der Spek, A. J. Vincent, J. M. Kros, H. M. Fathallah-Shaykh, O. Saut, J.-B. Lagaert, T. Colin, L. Araysi, Z. Tang, K. A. Duck, P. Ponnuru, E. B. Neely, J. R. Connor, M. Esencay, P. Gonzalez, A. Gaziel, Y. Safraz, H. Mira, E. Hernando, D. Zagzag, R. A. McDermott, I. Ulasov, N. Kaverina, P. Gabikian, M. Lesniak, A. Iranmahboob, M. Haber, G. Fatterpekar, E. Raz, D. Placantonakis, M. Eoli, C. Rabascio, L. Cuppini, E. Anghileri, S. Pellegatta, A. Calleri, P. Mancuso, P. Porrati, F. Bertolini, G. Finocchiaro, D. F. Seals, K. L. Burger, D. M. Gibo, W. Debinski, N. L. Tran, S. Tuncali, J. Kloss, Z. Yang, C. A. Schumacher, C. Diegel, J. T. Ross, B. O. Williams, J. M. Eschbacher, J. C. Loftus, M. Whiteman, M. Dombovy-Johnson, A. Vangellow, Y. Liu, E. Carson-Walter, K. A. Walter, K. Walter, N. Cortes-Santiago, K. Gabrusiewicz, D. Liu, M. B. Hossain, J. Gumin, X. Fan, C. Conrad, K. Aldape, M. Gilbert, A. Raghunathan, W. K. A. Yung, J. Fueyo, C. Gomez-Manzano, E. Bae, P. Huang, M. Burgett, G. Muller-Greven, N. Kar, C. L. Gladson, J. R. Engler, A. E. Robinson, A. Molinaro, J. J. Phillips, G. Zadeh, K. Burrell, R. Hill, Y. Piao, J. Liang, V. Henry, L. Holmes, E. Sulman, J. F. deGroot, J. F. de Groot, W. Rong, K. Funato, P. Georgala, F. Shimizu, L. Droms, V. Tabar, J. J. Parker, K. R. Dionne, R. Massarwa, M. Klaassen, N. K. Foreman, L. Niswander, P. Canoll, B. K. Kleinschmidt-DeMasters, A. Waziri

Publikováno v: Neuro-Oncology. 14:vi1-vi6

OBJECTIVE: Glioblastoma multiforme is the most frequent primary brain tumor in adults. The major obstacle for successful treatment is the invasive growth pattern. Metabolically, glioblastomas are highly glycolytic, leading to increased levels of lact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e132ca44ee428ab9072f8681150154e
https://doi.org/10.1093/neuonc/nos219

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Relationship between age at diagnosis and outcome of premenopausal breast cancer: age less than 35 years is a reasonable cut-off for defining young age-onset breast cancer

Autor: Wonshik, Han, So Young, Kang, S O, Yoon

Publikováno v: Breast Cancer Research and Treatment. 119:193-200

Previous studies have reported significantly worse outcomes in younger women with breast cancer. The cut-off for young age differed between studies and it is unclear whether the survival-age relationship is a linear function across age in premenopaus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff62a486c53146fecd1cbe5d874cae06
https://doi.org/10.1007/s10549-009-0388-z

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ZBP-89-induced apoptosis is p53-independent and requires JNK

Autor: Juanita L. Merchant, L Bai, P D King, S O Yoon

Publikováno v: Cell Death & Differentiation. 11:663-673

ZBP-89 induces apoptosis in human gastrointestinal cancer cells through a p53-independent mechanism. To understand the apoptotic pathway regulated by ZBP-89, we identified downstream signal transduction targets. Ectopic expression of ZBP-89 induced a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e045d24484d7d106542873d4d4616e
https://doi.org/10.1038/sj.cdd.4401393

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The biological functions and signaling mechanisms of the p75 neurotrophin receptor

Autor: B R, Kraemer, S O, Yoon, B D, Carter

Publikováno v: Handbook of experimental pharmacology. 220

The p75 neurotrophin receptor (p75(NTR)) regulates a wide range of cellular functions, including programmed cell death, axonal growth and degeneration, cell proliferation, myelination, and synaptic plasticity. The multiplicity of cellular functions g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8185063aebdf8b8c92087a8a5d02734a
https://pubmed.ncbi.nlm.nih.gov/24668472

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Akademický článek

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Triple negative breast cancer in Korea-distinct biology with different impact of prognostic factors on survival

Autor: Jung Ah, Lee, Kwan-Il, Kim, Jeoung Won, Bae, Young-Hoon, Jung, Hyonggin, An, Eun Sook, Lee, S O, Yoon

Publikováno v: Breast cancer research and treatment. 123(1)

We analyzed breast cancer subtypes using Korean Breast Cancer Society Registration Program data to compare clinical features and prognosis for triple-negative breast cancer (TNBC). A cohort of 26,767 breast cancer patients were divided in four groups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444d78933d6a690d7668c3c863598b98
https://pubmed.ncbi.nlm.nih.gov/20574671

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