Zobrazeno 1 - 10
of 149
pro vyhledávání: '"S.-M. Yong"'
Publikováno v:
Archives of Metallurgy and Materials, Vol vol. 63, Iss No 3, Pp 1485-1488 (2018)
The effect of additives on the densification behavior and mechanical properties of pure and additive (Zr, B and Mg)-added silica ceramics were investigated for their application to the matrix phase of a silica fiber reinforced silica (SiO2/SiO2f) com
Externí odkaz:
https://doaj.org/article/4e9f8aab5d414512af048a7932b8a278
Publikováno v:
Archives of Metallurgy and Materials, Vol vol. 63, Iss No 3, Pp 1481-1484 (2018)
Y2O3-MgO nanocomposites are one of the most promising materials for hypersonic infrared windows and domes due to their excellent optical transmittance and mechanical properties. In this study, influence of the calcination temperature of Y2O3-MgO nano
Externí odkaz:
https://doaj.org/article/d48eaa61919e4591aef29e46fece36a5
Autor:
Irma Telarovic, Carmen S. M. Yong, Lisa Kurz, Irene Vetrugno, Sabrina Reichl, Alba Sanchez Fernandez, Hung-Wei Cheng, Rona Winkler, Matthias Guckenberger, Anja Kipar, Burkhard Ludewig, Martin Pruschy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Cancer resistance to immune checkpoint inhibitors motivated investigations into leveraging the immunostimulatory properties of radiotherapy to overcome immune evasion and to improve treatment response. However, clinical benefits of radiother
Externí odkaz:
https://doaj.org/article/5e4fb3861c2944398416dd9f676c87db
Autor:
Peter Hillmen, Jing Xie, Alan S. M. Yong, Catherine Waweru, Thuy Anh Sorof, Ravi K. Goyal, Keith L. Davis
Publikováno v:
eJHaem, Vol 2, Iss 2, Pp 219-227 (2021)
Abstract Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in adults in the UK. Ibrutinib, an oral Bruton tyrosine kinase inhibitor (BTKi) for CLL approved by the UK's National Institute for Health and Care Excellence in January 2017,
Externí odkaz:
https://doaj.org/article/64a0d007117945a597b923277fa9e33d
Autor:
Yazad D. Irani, Chung H. Kok, Jade Clarson, Naranie Shanmuganathan, Susan Branford, David T. Yeung, David M. Ross, Timothy P. Hughes, Agnes S. M. Yong
Publikováno v:
Blood Advances. 7:2364-2374
Dysregulation of immune-checkpoint receptors has been reported at diagnosis of chronic myeloid leukemia (CML), however, their role in the maintenance of remission after tyrosine kinase inhibitor (TKI) cessation is unclear. We assessed programmed cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863ea30bd050ebfe93a90f31baaa89cd
https://doi.org/10.1182/bloodadvances.2022008854
https://doi.org/10.1182/bloodadvances.2022008854
Autor:
Agnes S. M. Yong, Amy Hughes
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Chronic myeloid leukemia (CML) is a hematological cancer, characterized by a reciprocal chromosomal translocation between chromosomes 9 and 22 [t(9;22)], producing the Bcr-Abl oncogene. Tyrosine kinase inhibitors (TKIs) represent the standard of care
Externí odkaz:
https://doaj.org/article/999547cc4cd44beab0b1ade6c37ca8f2
Autor:
Catherine Waweru, Peter Hillmen, Keith L. Davis, Ravi K. Goyal, Thuy Anh Sorof, Jing Xie, Alan S. M. Yong
Publikováno v:
eJHaem. 2:219-227
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in adults in the UK. Ibrutinib, an oral Bruton tyrosine kinase inhibitor (BTKi) for CLL approved by the UK's National Institute for Health and Care Excellence in January 2017, represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e58c67b8cf2fc57b4ee7277feb80924
https://doi.org/10.1002/jha2.174
https://doi.org/10.1002/jha2.174
Autor:
Markus G. Manz, Deborah L. White, Jade Clarson, Konrad Aumann, Angel F. Lopez, Cornelius Miething, Wenbo Yu, Timothy P. Hughes, Lutz Hein, Janaki Manoja Vinnakota, Amy Hughes, Sanaz Taromi, Robert Zeiser, Tony Matschulla, Justus Duyster, Khalid Shoumariyeh, Agnes S. M. Yong, Renier Myburgh, Michael P. Brown, Nadia El Khawanky
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Successful treatment of acute myeloid leukemia (AML) with chimeric antigen receptor (CAR) T cells is hampered by toxicity on normal hematopoietic progenitor cells and low CAR T cell persistence. Here, we develop third-generation anti-CD123 CAR T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade50715e480524133a7a77d2fb6b639
https://doi.org/10.1038/s41467-021-26683-0
https://doi.org/10.1038/s41467-021-26683-0
Autor:
Julie Perrault, Anais Rivière, Chloe Goldsmith, Jonas Dehairs, Cédric Mongellaz, Laurent Yvan-Charvet, Naomi Taylor, Valérie S. Zimmermann, Saverio Tardito, Maria I. Matias, Valerie Dardalhon, Océane Delos, Amir Foroushani, Kandice R. Levental, Stefan A. Muljo, Sandrina Kinet, Ilya Levental, Hector Hernandez-Vargas, Ali Talebi, Jean-Charles Portais, Justine Bertand-Michel, Madeline Wong, Ameeta Kelekar, Julien C. Marie, Johannes V. Swinnen, Carmen S M Yong, Erdinc Sezgin
Publikováno v:
Cell Reports
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive CD4 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0285e83f2c785c903977fe07dec51
https://lirias.kuleuven.be/handle/20.500.12942/691431
https://lirias.kuleuven.be/handle/20.500.12942/691431
Autor:
Carmen S M Yong, Jennifer A Westwood, Jan Schröder, Anthony T Papenfuss, Bianca von Scheidt, Maria Moeller, Christel Devaud, Phillip K Darcy, Michael H Kershaw
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140543 (2015)
Genetically modified CD8+ T lymphocytes have shown significant anti-tumor effects in the adoptive immunotherapy of cancer, with recent studies highlighting a potential role for a combination of other immune subsets to enhance these results. However,
Externí odkaz:
https://doaj.org/article/d4ac0e1592d94aa2813a1758c4f98a4c