Zobrazeno 1 - 10
of 25
pro vyhledávání: '"S.-C. Joseph Fu"'
Autor:
S.-C. Joseph Fu, Kaili Wu, Guan Ping Zhu, Harold I. Calvin, Wenjie Li, Ashley L. McCormack, Larry L. David
Publikováno v:
Experimental Eye Research. 75:335-346
Buthionine sulfoximine (BSO), a specific inhibitor of glutathione biosynthesis, induces oxidative cataracts following multiple injections into mice at 1 week of age. Cultures of lenses with 35S-methionine have previously demonstrated altered patterns
Publikováno v:
Experimental Eye Research. 54:611-619
L-buthionine-S,R-sulfoximine (BSO), a specific inhibitor of GSH biosynthesis, was administered four times daily to mouse pups on post-natal days 7 and 8, inducing initiation of opacification on day 9. The initial progression of the cataract (less tha
Publikováno v:
Experimental Eye Research. 54:621-626
Cataracts were induced in suckling mice by multiple injections of L-buthionine-S,R-sulfoximine (BSO), a specific inhibitor of GSH biosynthesis, starting on post-natal day 7. The earliest visible lens aberrations began approximately 2 days after t(o),
Publikováno v:
Experimental Eye Research. 51:79-85
Soluble lens crystallins from 6-10-week-old, galactose-fed, male Sprague-Dawley rats were analyzed by two-dimensional polyacrylamide gel electrophoresis at each of the five Sippel stages of cataractogenesis. Electrophoretograms were compared with sim
Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A
Publikováno v:
Current eye research. 27(5)
To compare the effects of two serine-threonine protein kinase inhibitors in a mouse lens culture system previously designed to investigate cortical cataracts caused by L-buthionine sulfoximine (BSO), inhibitor of GSH biosynthesis.Cataract development
Autor:
Wenjie, Li, Harold I, Calvin, Larry L, David, Kaili, Wu, Ashley L, McCormack, Guan-Ping, Zhu, S-C Joseph, Fu
Publikováno v:
Experimental eye research. 75(3)
Buthionine sulfoximine (BSO), a specific inhibitor of glutathione biosynthesis, induces oxidative cataracts following multiple injections into mice at 1 week of age. Cultures of lenses with (35)S-methionine have previously demonstrated altered patter
Publikováno v:
Experimental eye research. 54(5)
Enzymatic production of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] from exogenous arachidonic acid (AA) was studied in the 9000 g supernatant fraction of either whole rat lens or the capsule-epithelium and cortex-nucleus regions with age (4-180
Autor:
Calvin, Harold I., Kaili Wu, Harold I., Wenjie Li, Li Guo, Benerjee, Urmi, S.-C. Joseph Fu, Urmi
Publikováno v:
Current Eye Research; Nov2003, Vol. 27 Issue 5, p269, 10p
Publikováno v:
Experimental Eye Research. 27:627-635
Reversal of the galactose cataract in neonatal rat lenses involves a decrease in lenticular galactitol, a recovery of existing fiber contour and interdigitation, and a production of new fibers. The onset of neonatal cataractogenesis appeared at 7 day
Publikováno v:
Mechanisms of ageing and development. 31(1)
Lens endopeptidase activity and thermal stability have been determined as a function of (1) cell development, (2) cell age, and (3) animal age. Lenses from animals aged 3 months to 15 years (lens weights 1.15–2.80 g) were divided into epithelial (o