Zobrazeno 1 - 10
of 1 775
pro vyhledávání: '"S. Ziegler"'
Autor:
S. Cheng, X. Cheng, J. Ma, X. Xu, W. Zhang, J. Lv, G. Bai, B. Chen, S. Ma, S. Ziegler, S. Donner, T. Wagner
Publikováno v:
Atmospheric Chemistry and Physics, Vol 23, Pp 3655-3677 (2023)
The tropospheric concentrations of nitrogen dioxide (NO2) and formaldehyde (HCHO) have high spatio-temporal variability, and in situ observations of these trace gases are still scarce, especially in remote background areas. We made four similar circl
Externí odkaz:
https://doaj.org/article/0a42e015d6f24baa808a7a0ce755850f
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Peer-led tutorials are widely used in medical education to promote practical skills acquisition and support faculty staff. Typically, student tutors are custom trained for this specific task. We investigated whether opening up an
Externí odkaz:
https://doaj.org/article/30c21231c32446f5b722c480fb264e8b
Autor:
Jordan Staunton, Pamela Ajuyah, Angela Harris, Chelsea Mayoh, Marie Wong, Megan Rumford, Patricia J. Sullivan, Paul G. Ekert, Noemi Fuentes-Bolanos, Mark J. Cowley, Loretta M. S. Lau, David S. Ziegler, Paulette Barahona, Neevika Manoharan
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Noonan Syndrome (NS) is associated with an increased risk of low-grade central nervous system tumours in children but only very rarely associated with high-grade gliomas. Here we describe the first reported case of a spinal high-grade astroc
Externí odkaz:
https://doaj.org/article/f3ea3867fb7b4b96ba99217da50f78f6
Autor:
Eden G. Robertson, Kate Hetherington, Rebecca Daly, Mark W. Donoghoe, Nicholas Handelsman, David S. Ziegler, Claire E. Wakefield
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Patient‐reported outcomes measures (PROMs) are increasingly being collected within cancer clinical trials, yet limited literature on the feasibility and acceptability of doing so. Methods We collected parent‐proxy and adolesce
Externí odkaz:
https://doaj.org/article/c410b79109df4d86876e4705fb6a2e02
Autor:
Cornelis M. van Tilburg, Lindsay B. Kilburn, Sébastien Perreault, Rene Schmidt, Amedeo A. Azizi, Ofelia Cruz-Martínez, Michal Zápotocký, Katrin Scheinemann, Antoinette Y. N. Schouten-van Meeteren, Astrid Sehested, Enrico Opocher, Pablo Hernáiz Driever, Shivaram Avula, David S. Ziegler, David Capper, Arend Koch, Felix Sahm, Jiaheng Qiu, Li-Pen Tsao, Samuel C. Blackman, Peter Manley, Till Milde, Ruth Witt, David T. W. Jones, Darren Hargrave, Olaf Witt
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549::BRAF fusions and
Externí odkaz:
https://doaj.org/article/6042d3662e6a4c2d9fc8d41531bad22c
Autor:
S. J. Jessop, N. Fuentos‐Bolanos, C. Mayoh, M. E. M. Dolman, G. Tax, M. Wong‐Erasmus, P. Ajuyah, V. Tyrell, G. M. Marshall, D. S. Ziegler, L. M. S. Lau
Publikováno v:
Cancer Reports, Vol 7, Iss 4, Pp n/a-n/a (2024)
Abstract Background Despite advances in therapeutics for adverse‐risk acute myeloid leukaemia (AML), overall survival remains poor, especially in refractory disease. Comprehensive tumour profiling and pre‐clinical drug testing can identify effect
Externí odkaz:
https://doaj.org/article/a1e5a028813d4920bdd7d8ade437319d
Autor:
Carolyn G. Mazariego, Skye McKay, Elijah Tyedmers, Lauren Kelada, Brittany C. McGill, Rebecca Daly, Claire E. Wakefield, David S. Ziegler, Natalie Taylor
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
ObjectivesPaediatric oncologists often encounter challenges when seeking compassionate access to off-label therapies for their patients. This study employed implementation science and co-design techniques to develop the ProCure medicines database, wi
Externí odkaz:
https://doaj.org/article/8abf31985bfa47b2a579f84840cc599c
The UK's engagement with the legal protection of human rights at a European level has been, at varying stages, pioneering, sceptical and antagonistic. The UK government, media and public opinion have all at times expressed concerns about the growing
Autor:
Aaminah Khan, Laura D. Gamble, Dannielle H. Upton, Caitlin Ung, Denise M. T. Yu, Anahid Ehteda, Ruby Pandher, Chelsea Mayoh, Steven Hébert, Nada Jabado, Claudia L. Kleinman, Mark R. Burns, Murray D. Norris, Michelle Haber, Maria Tsoli, David S. Ziegler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Diffuse intrinsic pontine glioma (DIPG) is an almost incurable malignant childhood brain tumor. Here, the authors show that the polyamine synthetic pathway is activated in DIPG and that the dual targeting of polyamine synthesis and uptake results in
Externí odkaz:
https://doaj.org/article/4116e5b63fd745dd8d4fa955d44571c8
Autor:
Sumanth Nagabushan, Loretta M. S. Lau, Paulette Barahona, Marie Wong, Alexandra Sherstyuk, Glenn M. Marshall, Vanessa Tyrrell, Eva A. Wegner, Paul G. Ekert, Mark J. Cowley, Chelsea Mayoh, Toby N. Trahair, Philip Crowe, Antoinette Anazodo, David S. Ziegler
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-6 (2021)
Abstract The prognosis of recurrent malignant peripheral nerve sheath tumors (MPNST) is dismal, with surgical resection being the only definitive salvage therapy. Treatment with chemoradiation approaches has not significantly improved patient outcome
Externí odkaz:
https://doaj.org/article/1017be47b03249d190e20ce279c78746