Zobrazeno 1 - 10
of 11
pro vyhledávání: '"S. Z. Cagen"'
Autor:
E W, Carney, A M, Hoberman, D R, Farmer, R W, Kapp, A I, Nikiforov, M, Bernstein, M E, Hurtt, W J, Breslin, S Z, Cagen, G P, Daston
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 11(6)
Recent concerns about the potential of certain chemicals to modulate estrogen-regulated processes have led to questions as to how chemicals should be tested for such effects. Therefore, AIHC has developed a comprehensive, resource-efficient, and flex
Autor:
J E Gibson, S Z Cagen
Publikováno v:
Environmental Health Perspectives
The purpose of this investigation was to determine the influence of polybrominated biphenyls (PBBs) on hepatic excretory function in developing and adult rats and mice. Prenatal or postnatal dietary exposure to PBBs (50 ppm in diet of pregnant or lac
Publikováno v:
Journal of the American College of Toxicology. 6:233-243
Testicular effects induced by dermal application or dust inhalation of para-tertiary butyl benzoic acid (ptBBA) in Fischer 344 rats were investigated. Similar effects were observed from both dermal and dust inhalation studies. Reduction in testis wei
Publikováno v:
Journal of the American College of Toxicology. 8:1027-1038
The subchronic dermal toxicity of aqueous solutions containing the diethanolamine salt of para-tertiary butyl benzoic acid was determined in Fischer 344 rats. Para-tertiary butyl benzoic acid (pt BBA) has important applications in the manufacture of
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 198(1)
Paraquat poisoning may result in pulmonary damage and hepatotoxicity. To examine the effect of paraquat on liver function, paraquat-treated mice were injected with sulfobromophthalein (BSP, 100 mg/kg) or indocyanine green (20 mg/kg) via the tail vein
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 7(5)
Autor:
C D, Klaassen, S Z, Cagen
Publikováno v:
Advances in experimental medicine and biology.
Autor:
James E. Gibson, S. Z. Cagen
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 154(2)
SummaryCC14 depressed hepatic excretory function in adult and developing rats. In this regard, plasma ouabain concentrations were significantly higher and biliary (intestinal) ouabain was significantly lower in the treated animals. Of particular inte
Autor:
S Z, Cagen, J E, Gibson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 210(1)
The purpose of this investigation was to characterize the development of hepatic excretory function in rats. Cumulative (40 min) intestinal ouabain content was lower and plasma ouabain concentrations were higher in 15-day-old rats than in 21-, 25-, 3
Autor:
S Z, Cagen, C D, Klaasen
Publikováno v:
Federation proceedings. 39(13)
This investigation was designed to evaluate carbon tetrachlorid (CCl4)-induced hepatotoxicity in developing rats and in adult rats pretreated with zinc. Hepatotoxicity of CCl4 in rats as young as 4 days of age was similar to that in adults. However,