Zobrazeno 1 - 10
of 20
pro vyhledávání: '"S. Ya. Proskuryakov"'
Autor:
V.G. Skvortsov, L. D. Smirnov, S. Ya. Proskuryakov, T. N. Nosko, Yu. V. Kuznetsov, A. E. Dontsov
Publikováno v:
Biophysics. 56:276-280
The antiradical and NO-inhibiting activities of β-hydroxy(ethoxy) derivatives of nitrous heterocycles (3-hydroxypyridine, 5-hydroxybenzimodazole, and 6-hydroxy(alkoxy)-benzothiazole) have been studied. The antiradical activity has been studied using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::419e58ae01446409292a18bac94766f9
https://doi.org/10.1134/s000635091102028x
https://doi.org/10.1134/s000635091102028x
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 5:1-9
Using stem cells as an example the review considers a new history and methodology of search for stem cells (SC), found in tissues of adult Homo sapiens and Drosophila melanogaster organisms. These studies of SC resulted in several original hypotheses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ccd186081f792019e4dcc67230fca3
https://doi.org/10.1134/s1990750811010100
https://doi.org/10.1134/s1990750811010100
Autor:
A. A. Mandrugin, Alexey N. Proshin, V. M. Fedoseev, Ya. I. Lys, Olga N. Zefirova, T. P. Trofimova, A. N. Pushin, S. Ya. Proskuryakov
Publikováno v:
Moscow University Chemistry Bulletin. 64:289-293
The present work deals with the synthesis of sixteen compounds with putative inhibiting activity towards NO-synthase on the basis of 2-amino-2-thiazoline and 2-amino-5,6-dihydro-4H-1,3-thiazine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51cfc69124f6ca3a084fd15eaae6937b
https://doi.org/10.3103/s0027131409050101
https://doi.org/10.3103/s0027131409050101
Autor:
A. G. Konoplyannikov, D. Yu. Logunov, B. S. Narodicky, A. L. Gincburg, S. Ya. Proskuryakov, L. P. Ulyanova
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 3:221-236
The thanatogenetic mechanisms of stem cells (sc) of rapidly renewing system of intestinal epithelium still remain unclear. on the one hand they are definitely involved into basic mechanisms of carcinogenesis in the gastrointestinal tract, because dys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2271736eaf7b9f29e16c7c374d49ff8e
https://doi.org/10.1134/s1990750809030020
https://doi.org/10.1134/s1990750809030020
Autor:
V. M. Fedoseev, S. Ya. Proskuryakov, Olga N. Zefirova, Natalia V. Gulyaeva, T. P. Trofimova, Mikhail V. Onufriev, A. A. Mandrugin, D. I. Peregud
Publikováno v:
Moscow University Chemistry Bulletin. 63:274-277
The synthesis and results of in vitro and in vivo testing of 2-N-acetylamino-, 2-N-benzoylamino-,2-N-cyclohexanecarbonylamino-, and 2-N-(1-adamantanecarbonyl)amino-5,6-dihydro-4H-1,3-thiazines for NOS-inhibiting activity have been described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6578e6024f4496a35c9520c9d3759df6
https://doi.org/10.3103/s0027131408050088
https://doi.org/10.3103/s0027131408050088
Autor:
V. M. Fedoseev, A. N. Pushin, Alexey N. Proshin, Adam I. Stash, A. A. Mandrugin, T. P. Trofimova, S. Ya. Proskuryakov
Publikováno v:
Chemistry of Heterocyclic Compounds. 43:370-376
A simple and convenient method is proposed for the synthesis of 2-amino-5-hydroxymethylthiazolines with various substituents in the amino group, which is based on hydrolysis of the corresponding 5-halomethyl derivatives of thiazoline in the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff908f0900cb43b9fc909c87af80f3d5
https://doi.org/10.1007/s10593-007-0054-5
https://doi.org/10.1007/s10593-007-0054-5
Publikováno v:
Biochemistry (Moscow). 70:8-23
Synthesis of compounds containing a fragment similar to the guanidine group of L-arginine, which is a substrate of nitric oxide synthase (NOS), is the main direction in creating NOS inhibitors. The inhibitory effect of such compounds is caused not on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343ba673ba39e1d4976cd2f25676c7b2
https://doi.org/10.1007/s10541-005-0048-9
https://doi.org/10.1007/s10541-005-0048-9
Autor:
A. A. Mandrugin, T. P. Trofimova, A. N. Proschin, S. Ya. Proskuryakov, L. I. Shtein, A. N. Pushin, V. M. Fedoseev
Publikováno v:
Pharmaceutical Chemistry Journal. 41:640-642
A series of 2-amino-2-thiazoline derivatives have been synthesized and characterized with respect to NOS-inhibitor activity in vivo. It was established that the dimensions of the substituents in 2-N-mono-and 2-N,N-disubstituted 2-amino-2-thiazolines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884e367209dcf6718472f18807bce5a6
https://doi.org/10.1007/s11094-008-0029-6
https://doi.org/10.1007/s11094-008-0029-6
Publikováno v:
Bulletin of experimental biology and medicine. 146(4)
In vivo experimental studies showed that 1,2-dimethylhydrazine and product of its metabolism in the body azoximethane improve postradiation survival of two types of stem cells in the adult organism: hemopoietic stem cells and intestinal epithelial st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016db0b8893dc153c47d9c5b97b6f909
https://pubmed.ncbi.nlm.nih.gov/19489337
https://pubmed.ncbi.nlm.nih.gov/19489337
Autor:
S. Ya. Proskuryakov, O. A. Konoplyannikova, A. G. Konoplyannikov, Yu. G. Verkhovskii, A. F. Tsyb, L. I. Shevchenko
Publikováno v:
Biochemistry. Biokhimiia. 74(2)
Pifithrin alpha (PFTalpha), one of the first known low molecular weight modulators of activity of tumor suppressor p53, increases survival of hemopoietic clonogenic cells (evaluated by the criterion of formation of endogenous spleen CFU-C8 colonies i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be815688ea234ef54afe1079874865f
https://pubmed.ncbi.nlm.nih.gov/19267667
https://pubmed.ncbi.nlm.nih.gov/19267667