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pro vyhledávání: '"S. Xiaohu Ouyang"'
Autor:
Thomas D.Y. Chung, Sharon A. Colayco, Baozong Li, Li Du, Jianghai Wang, Yi-Jia Li, Ramir Vega, Daniela B. Divlianska, Grace Aldana-Masangkay, Ekaterina V. Bobkova, Terry D. Lee, Yunan Miao, Marwan Fakih, Eduard Sergienko, Yuan Chen, S. Xiaohu Ouyang, Eric R. Samuels
Publikováno v:
Cell chemical biology. 26(2)
Summary Ubiquitin-like (Ubl) post-translational modifications are potential targets for therapeutics. However, the only known mechanism for inhibiting a Ubl-activating enzyme is through targeting its ATP-binding site. Here we identify an allosteric i