Zobrazeno 1 - 10
of 332
pro vyhledávání: '"S. Worgall"'
Autor:
Cheng Fu, Nan Yang, Jen-Zen Chuang, Nobuyuki Nakajima, Satoshi Iraha, Neeta Roy, Zhenquan Wu, Zhichun Jiang, Wataru Otsu, Roxana A. Radu, Howard Hua Yang, Maxwell Ping Lee, Tilla S. Worgall, Wen-Cheng Xiong, Ching-Hwa Sung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Vacuolar protein sorting 35 (VPS35), the core component of the retromer complex which regulates endosomal trafficking, is genetically linked with Parkinson’s disease (PD). Impaired vision is a common non-motor manifestation of PD. Here, we
Externí odkaz:
https://doaj.org/article/6795212de22b42e1b120beca529a58fb
Autor:
Andrea Heras, Rika Gomi, Madeline Young, Chuchun L. Chang, Emily Wasserman, Anurag Sharma, Wenzhu Wu, Jinghua Gu, Uthra Balaji, Rachel White, Perdita Permaul, Ibrahim Janahi, Tilla S. Worgall, Stefan Worgall
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential nutrients that can affect inflammatory responses. While n-3 PUFAs are generally considered beneficial for cardiovascular disease and obesity, the effects on asthma, the most commo
Externí odkaz:
https://doaj.org/article/1cac500eb2644807bce62ac667718b5f
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Tapia-Alveal, Olsen and Worgall develop a novel strategy for patient-specific multiple myeloma diagnostics platform using DNA aptamers. The high affinity DNA aptamers enabled detection of minimal residual disease (MRD) when conventional MRD methods a
Externí odkaz:
https://doaj.org/article/4eae892611494e1689d790423c725031
Autor:
Elizabeth L. Johnson, Stacey L. Heaver, Jillian L. Waters, Benjamin I. Kim, Alexis Bretin, Andrew L. Goodman, Andrew T. Gewirtz, Tilla S. Worgall, Ruth E. Ley
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Ceramides are a type of sphingolipid (SL) that have been shown to play a role in several metabolic disorders. Here, the authors investigate the effect of SL-production by gut Bacteroides on host SL homeostasis and show that microbiome-derived SLs ent
Externí odkaz:
https://doaj.org/article/a946ac4716d946b782e0ae26fb93f95f
Autor:
Gregory M. LaMonte, Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth, Tilla S. Worgall, Gregory M. Goldgof, Roxanne Mohunlal, T. R. Santha Kumar, Jennifer K. Thompson, Edgar Vigil, Jennifer Yang, Dylan Hutson, Trevor Johnson, Jianbo Huang, Roy M. Williams, Bing Yu Zou, Andrea L. Cheung, Prianka Kumar, Timothy J. Egan, Marcus C. S. Lee, Dionicio Siegel, Alan F. Cowman, David A. Fidock, Elizabeth A. Winzeler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Imidazolopiperazines (IZPs) are a class of compounds under clinical development for malaria, but their mechanism of action is unclear. Here, the authors show that IZPs inhibit the parasite’s secretory pathway, affecting protein trafficking and expo
Externí odkaz:
https://doaj.org/article/30325ebc8f1440eb95a7ef787cbdca69
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103449- (2021)
Summary: Glucosylceramide (GluCer) was accumulated in sphingomyelin synthase 1 (SMS1) but not SMS2 deficient mouse tissues. In current study, we studied GluCer accumulation-mediated metabolic consequences. Livers from liver-specific Sms1/global Sms2
Externí odkaz:
https://doaj.org/article/c1534ea8bb3b4764a344f509814da050
Autor:
J. P. Dyke, A. Voskrebenzev, L. K. Blatt, J. Vogel-Claussen, R. Grimm, S. Worgall, J. M. Perlman, A. Kovanlikaya
Publikováno v:
Pediatric Radiology. 53:1076-1084
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88dbc32783ec0a4d8c92d0085c3e4975
https://doi.org/10.1007/s00247-023-05598-6
https://doi.org/10.1007/s00247-023-05598-6
Publikováno v:
BMC Anesthesiology, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Airway instrumentation can evoke upper airway reflexes including bronchoconstriction and cough which can cause serious complications including airway trauma, laryngospasm or bronchospasm which may in turn lead to difficulty with v
Externí odkaz:
https://doaj.org/article/337aa89a58ce43848cedcf77391e8b43
Publikováno v:
C60. CHILDHOOD INTERSTITIAL LUNG DISEASE (chILD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b93eaf4a5ccb6b863d6f0758f72d93
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5468
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5468
Publikováno v:
A13. ASTHMA, THE NEXT FRONTIER: NEW DEVELOPMENTS IN PATHOPHYSIOLOGY AND TREATMENT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd26ca52dbfcdbfd9354374643bec29
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1003
https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1003