Longitudinal changes in gray matter correspond to changes in cognition across the lifespan: implications for theories of cognition

Autor: Evan T. Smith, Joseph P. Hennessee, Gagan S. Wig, Sarah Frank, Hector Gonzalez, Julia Bacci, Micaela Chan, Claudia A. Carreno, Kristen M. Kennedy, Karen M. Rodrigue, Christopher Hertzog, Denise C. Park

Publikováno v: Neurobiology of Aging. 129:1-14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e392a334c222665f66b7ade4ab4ab64b
https://doi.org/10.1016/j.neurobiolaging.2023.04.014

The relationship of functional hippocampal activity, amyloid deposition, and longitudinal memory decline to memory complaints in cognitively healthy older adults

Autor: Denise C. Park, Michelle E. Farrell, Gagan S. Wig, Melissa M. Rundle, William Moore, Micaela Y. Chan, Xi Chen

Publikováno v: Neurobiology of Aging. 105:318-326

We evaluated whether self-reports of worse cognition in older adults with normal cognitive function reflected actual memory decline, amyloid pathology, and subtle vulnerabilities in hippocampal function. We measured subjective cognitive decline (SCD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0464a9f2a4c8728d5cf15df39e5404ca
https://doi.org/10.1016/j.neurobiolaging.2021.04.020

Relationship of prefrontal brain lateralization to optimal cognitive function differs with age

Autor: Joseph P. Hennessee, Christina E. Webb, Xi Chen, Kristen M. Kennedy, Gagan S. Wig, Denise C. Park

Publikováno v: NeuroImage. 264

There is considerable debate about whether additional fMRI-measured activity in the right prefrontal cortex readily observed in older adults represents compensatory activation that enhances cognition or whether maintenance of youthful brain activity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649114692b3c782dc0d581cbc790e2ff
https://pubmed.ncbi.nlm.nih.gov/36396072

Parallel hippocampal-parietal circuits for self- and goal-oriented processing

Autor: Gagan S. Wig, Dimitrios Alexopoulos, Nicole A Seider, Scott Marek, Marcus E. Raichle, Joshua S. Shimony, Steven M. Nelson, Bradley L. Schlaggar, Andrew N. Van, Dillan J. Newbold, Deanna J. Greene, Evan M. Gordon, Annie Zheng, Jacqueline M. Hampton, Caterina Gratton, Nico U.F. Dosenbach, Kathleen B. McDermott, David F. Montez, Timothy O. Laumann, Benjamin P Kay, Adrian W. Gilmore, Chad M. Sylvester

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 34
Proceedings of the National Academy of Sciences of the United States of America

Significance The finding that human hippocampal-cortical functional connectivity is nonunitary, separated along functional network borders (default mode network [DMN], self-oriented; parietal memory network [PMN], goal-oriented) in the anterior–pos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b0881588f847bac48d6d9e5579b509
https://escholarship.org/uc/item/7pr7t1wj

Parallel Hippocampal-Parietal Circuits for Self- and Goal-oriented Processing

Autor: Joshua S. Shimony, Gagan S. Wig, Annie Zheng, Steven M. Nelson, David F. Montez, Dimitrios Alexopolous, Kathleen B. McDermott, Nicole A Seider, Nico U.F. Dosenbach, Deanna J. Greene, Adrian W. Gilmore, Marcus E. Raichle, Timothy O. Laumann, Scott Marek, Dillan J. Newbold, Chad M. Sylvester, Andrew N. Van, Bradley L. Schlaggar, Evan M. Gordon, Benjamin P Kay, Jacqueline M. Hampton, Caterina Gratton

SUMMARYThe hippocampus is critically important for a diverse range of cognitive processes, such as episodic memory, prospective memory, affective processing, and spatial navigation. The human hippocampus has been thought of as being solely functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93d4fa6502088701c129cd033104fc55
https://doi.org/10.1101/2020.12.01.395210