Zobrazeno 1 - 10
of 34
pro vyhledávání: '"S. Wiederkum"'
Autor:
R. Kircheis, Andreas Nechansky, N. Halanek, P. Siegl, Oliver Szolar, I. Zinoecker, S. Wiederkum
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 49:1014-1020
The fully humanized Lewis-Y carbohydrate specific monoclonal antibody (mAb) IGN311 is currently tested in a passive immunotherapy approach in a clinical phase I trail and therefore regulatory requirements demand qualified assays for product analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c9dbe6a7a0abf414fe630e5f2feeb2
https://doi.org/10.1016/j.jpba.2009.01.029
https://doi.org/10.1016/j.jpba.2009.01.029
Publikováno v:
Cytotechnology. 39:37-45
In this publication different detachment factors were tested for enhancing carrier to carrier transfer for scale-up of macroporous microcarrier based bioprocesses. Two Chinese hamster ovary cell lines, CHO-K1 and a genetically engineered CHO-K1 deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c7904c7cba4f284c55c7dfd17a08300
https://doi.org/10.1023/a:1022455525323
https://doi.org/10.1023/a:1022455525323
Publikováno v:
Cytotechnology. 39(1)
In this publication different detachment factors were tested for enhancing carrier to carrier transfer for scale-up of macroporous microcarrier based bioprocesses. Two Chinese hamster ovary cell lines, CHO-K1 and a genetically engineered CHO-K1 deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfab013f3743a92046fa819bad9fa425
https://pubmed.ncbi.nlm.nih.gov/19003302
https://pubmed.ncbi.nlm.nih.gov/19003302
Autor:
F. Unterluggauer, Hermann Katinger, Karola Vorauer-Uhl, C. Schmatz, S. Wiederkum, Günther Kreismayr, A. Assadian, S. Preis, Otto Doblhoff-Dier, D. Müller
Publikováno v:
Animal Cell Technology: Products from Cells, Cells as Products ISBN: 9780792360759
The following items emerged to be critical when optimizing this proteinfree high cell density perfusion process the initial cell density, cell viability and the stage of cell growth the procedures for the cell attachment phase a well balanced medium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2d6ab6b4102ff2a1d5ea5af0ae95d38
https://doi.org/10.1007/0-306-46875-1_71
https://doi.org/10.1007/0-306-46875-1_71
Autor:
Gordana Simic, G. Blüml, Markus Dürrschmid, Helga Klug, Hermann Katinger, Karlheinz Landauer, S. Wiederkum, Otto Doblhoff-Dier
Publikováno v:
Animal Cell Technology: From Target to Market ISBN: 9789401038973
Many pharmaceutical companies have developed their own protein-free medium for the production of bio-pharmaceuticals to eliminate animal derived media components. In many cases, using such media the morphology and the adherence of animal cells change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e236506b93306fa05fb8ccbd69fa97f6
https://doi.org/10.1007/978-94-010-0369-8_82
https://doi.org/10.1007/978-94-010-0369-8_82
Autor:
W. Steinfellner, Hermann Katinger, S. Wiederkum, C. Schmatz, O. Doblhoff-Dier, G. Blüml, A. Assadian, D. Müller, G. Lhota, G. Kreismayr, G. Klima
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
Monoclonal antibodies for passive immunotherapy demand for cheap large scale manufacturing technologies. Previous studies showed that fluidized bed reactors (FBR) are a promising production system considering scale up potential and volumetric product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c4304a794ce04509c5e69042750a06b
https://doi.org/10.1007/978-94-011-5404-8_71
https://doi.org/10.1007/978-94-011-5404-8_71
Autor:
G. Blüml, W. Steinfellner, D. Müller, G. Kreismayr, C. Schmatz, S. Wiederkum, A. Assadian, Hermann Katinger, O. Doblhoff-Dier, G. Klima, G. Lhota
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
To optimize cell density and productivity several lab-scale fermentations in a fluidized bed reactor (Cytopilot-Mini™, Pharmacia Biotech) have been carried out with recombinant CHO cells immobilized on macroporous microcarriers (Cytoline™ 1, Phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::886896855c2aee356e54100e2829147a
https://doi.org/10.1007/978-94-011-5404-8_72
https://doi.org/10.1007/978-94-011-5404-8_72
Autor:
R. Kircheis, P. Regitnik, W. Weizer, S. Wiederkum, M. Kainer, G. Waxenecker, Thomas Bauernhofer, H. Samonigg, Hans Loibner, B. Lileg
Publikováno v:
Journal of Clinical Oncology. 24:2547-2547
2547 Background: Treatment of CRC patients (pts) with the humanized mAb IGN311 targeting the carbohydrate Lewis Y eliminated circulating tumor cells in blood and thereby confirmed the clinical profile of the parent murine antibody ABL364, which showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2880ae0e56f2192d8a0c7c94dbd1b341
https://doi.org/10.1200/jco.2006.24.18_suppl.2547
https://doi.org/10.1200/jco.2006.24.18_suppl.2547
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