Predictable NHEJ Insertion and Assessment of HDR Editing Strategies in Plants

Autor: Kutubuddin A. Molla, Justin Shih, Matthew S. Wheatley, Yinong Yang

Publikováno v: Frontiers in Genome Editing, Vol 4 (2022)

Canonical CRISPR-Cas9 genome editing technique has profoundly impacted the fields of plant biology, biotechnology, and crop improvement. Since non-homologous end joining (NHEJ) is usually considered to generate random indels, its high efficiency muta

Externí odkaz: https://doaj.org/article/2e22fdb8f62f449ea2b28166617d5f72

Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma

Autor: Jordan F. Hastings, Sharissa L. Latham, Alvin Kamili, Madeleine S. Wheatley, Jeremy Z. R. Han, Marie Wong-Erasmus, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L. Cadell, Yolande E. I. O’Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D. Norris, Michelle Haber, Toby N. Trahair, Frank Speleman, Katleen De Preter, Mark J. Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R. Cox, Walter Kolch, Jamie I. Fletcher, Dirk Fey, David R. Croucher

Publikováno v: SCIENCE ADVANCES

Gene expression noise is known to promote stochastic drug resistance through the elevated expression of individual genes in rare cancer cells. However, we now demonstrate that chemoresistant neuroblastoma cells emerge at a much higher frequency when

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c49f49836711aef2f34b98a0e86d38d
https://doi.org/10.1126/sciadv.abp8314

How reproducible are surface areas calculated from the BET equation?

Autor: Christian Serre, Peyman Z. Moghadam, Feng P, Rama Oktavian, Lin R, Ting, Telalovic S, Omar M. Yaghi, Mark D. Allendorf, Russell E. Morris, Muhammad Sadiq, Philip L. Llewellyn, Jonathan L. Snider, Stavila, Matthew J. Rosseinsky, Hou B, Pütz A, Daniel W. Siderius, Rowlandson J, Randall Q. Snurr, van der Veen M, Nguyen T, Kaneko K, Linares N, Félix Zamora, Zhou H, Camille Petit, Sebastian T. Emmerling, Aran Lamaire, Cui Y, David G. Madden, Salcedo-Abraira P, Krista S. Walton, Soumya Mukherjee, Karam B. Idrees, Doheny Pw, Timur Islamoglu, Azevedo Dcs, Conchi O. Ania, Bu X, Zang X, Martin Schröder, Vilarrasa-García E, Michael T. Huxley, Ken-ichi Otake, Sanchez E, Rega D, Vanspeybroeck, Georges Mouchaham, Carmen Montoro, Lee Sj, David Danaci, Goncalves Rb, Yamil J. Colón, Patricia Horcajada, David S. Sholl, David Fairen-Jimenez, Shane G. Telfer, Bethany M. Connolly, Christian J. Doonan, Ryan P. Lively, D’Alessandro D, Raffaele Ricco, Paul S. Wheatley, Clowes R, Bettina V. Lotsch, Alexandros P. Katsoulidis, François-Xavier Coudert, Dominic Bara, Garcia-Martinez J, Carlos Martí-Gastaldo, Yavuz C, Chen B, Matthew R. Hill, Ross S. Forgan, Shuhei Furukawa, Ghosha Sk, Johannes W.M. Osterrieth, Jack D. Evans, Jorge A. R. Navarro, Suarez Ja, Zhang B, João Marreiros, Jorge Gascon, Neil R. Champness, Kenvin J, Yang S, Iiyuka T, Nakul Rampal, Daniel Maspoch, falcaro p, Rampersad J, Han X, Jacopo Andreo, Benoit Coasne, Yang H, Angelo K, Stefan Wuttke, Santos Bf, Chenyue Sun, Susumu Kitagawa, Luka Skoric, Moreton Jc, Rob Ameloot, Muñoz N, DeWitt Sja, Uemura T, Sven Rogge, Seda Keskin, Lukas W. Bingel, Raghuram Thyagarajan, Mircea Dincă, Seth M. Cohen, Bunzen H, Kukobat R, Omar K. Farha, Sarah L. Griffin, Chen L

Publikováno v: Advanced Materials
Advanced Materials, 2022, 34 (27), pp.2201502. ⟨10.1002/adma.202201502⟩
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Advanced Materials, Wiley-VCH Verlag, 2022, pp.2201502. ⟨10.1002/adma.202201502⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digibug. Repositorio Institucional de la Universidad de Granada
instname
ADVANCED MATERIALS
Osterrieth, J W M, Rampersad, J, Madden, D, Rampal, N, Skoric, L, Connolly, B, Allendorf, M D, Stavila, V, Snider, J L, Ameloot, R, Marreiros, J, Ania, C, Azevedo, D, Vilarrasa-garcia, E, Santos, B F, Bu, X, Chang, Z, Bunzen, H, Champness, N R, Griffin, S L, Chen, B, Lin, R, Coasne, B, Cohen, S, Moreton, J C, Colón, Y J, Chen, L, Clowes, R, Coudert, F, Cui, Y, Hou, B, D'alessandro, D M, Doheny, P W, Dincă, M, Sun, C, Doonan, C, Huxley, M T, Evans, J D, Falcaro, P, Ricco, R, Farha, O, Idrees, K B, Islamoglu, T, Feng, P, Yang, H, Forgan, R S, Bara, D, Furukawa, S, Sanchez, E, Gascon, J, Telalović, S, Ghosh, S K, Mukherjee, S, Hill, M R, Sadiq, M M, Horcajada, P, Salcedo-abraira, P, Kaneko, K, Kukobat, R, Kenvin, J, Keskin, S, Kitagawa, S, Otake, K, Lively, R P, Dewitt, S J A, Llewellyn, P, Lotsch, B V, Emmerling, S T, Pütz, A M, Martí-gastaldo, C, Padial, N M, García-martínez, J, Linares, N, Maspoch, D, Suárez Del Pino, J A, Moghadam, P, Oktavian, R, Morris, R E, Wheatley, P S, Navarro, J, Petit, C, Danaci, D, Rosseinsky, M J, Katsoulidis, A P, Schröder, M, Han, X, Serre, C, Mouchaham, G, Sholl, D S, Thyagarajan, R, Siderius, D, Snurr, R Q, Goncalves, R B, Telfer, S, Lee, S J, Ting, V P, Rowlandson, J L, Uemura, T, Iiyuka, T, Veen, M A, Rega, D, Van Speybroeck, V, Rogge, S M J, Lamaire, A, Walton, K S, Bingel, L W, Wuttke, S, Andreo, J, Yaghi, O, Zhang, B, Yavuz, C T, Nguyen, T S, Zamora, F, Montoro, C, Zhou, H, Kirchon, A & Fairen-jimenez, D 2022, ' How Reproducible are Surface Areas Calculated from the BET Equation? ', Advanced Materials, vol. 34, no. 27, 2201502 . https://doi.org/10.1002/adma.202201502

This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (NanoMOFdeli), ERC-2016-COG 726380, Innovate UK (104384) and EPSRC IAA (IAA/RG85685). N.R. acknowledg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dc175baaf3805a23735e073be21852
https://hdl.handle.net/10023/25464

Synthetic and Crystallographic Investigation of the Layered Coordination Framework Copper-1,3-bis(4-carboxyphenyl)-5-ethoxybenzene

Autor: David B. Cordes, Paul S. Wheatley, Lauren N. McHugh, Alexandra M. Z. Slawin, Russell E. Morris

Publikováno v: Crystal Growth & Design. 20:39-42

The reaction of 1,3-bis(4-carboxyphenyl)-5-ethoxybenzene and copper acetate monohydrate yields copper-1,3-bis(4-carboxyphenyl)-5-ethoxybenzene(DMF), and upon removal of coordinated DMF molecules, copper-1,3-bis(4-carboxyphenyl)-5-ethoxybenzene is att

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4282a853ca2b5d8d58698114083d8735
https://doi.org/10.1021/acs.cgd.9b01369

GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators

Autor: Kimberley M. Hanssen, Madeleine S. Wheatley, Denise M. T. Yu, Gwenaëlle Conseil, Murray D. Norris, Michelle Haber, Susan P. C. Cole, Jamie I. Fletcher

Publikováno v: The FEBS journalReferences. 289(13)

MRP1 (ABCC1) is a membrane transporter that confers multidrug resistance in cancer cells by exporting chemotherapeutic agents, often in a reduced glutathione (GSH)-dependent manner. This transport activity can be altered by compounds (modulators) tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5b11247b01f99de4da5d91dd0c887d
https://pubmed.ncbi.nlm.nih.gov/35080351