Zobrazeno 1 - 10
of 87
pro vyhledávání: '"S. Wayne Mascarella"'
Autor:
Frank Ivy Carroll, Xing Zhang, Philip Abraham, S. Wayne Mascarella, Judith Flippen-Anderson, Jeffrey R. Deschamps
Publikováno v:
ARKIVOC, Vol 2010, Iss 4, Pp 96-103 (2010)
Externí odkaz:
https://doaj.org/article/cb966ffc5a9647429d7b89e659116c0d
Publikováno v:
Annals of the New York Academy of Sciences. 1489:48-77
During 2012-2018, the clandestine manufacture of new psychoactive substances (NPS) designed to circumvent substance control regulations increased exponentially worldwide, with concomitant increase in fatalities. This review focuses on three compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37380b12d1f1da8fbce1c3d9085a4fab
https://doi.org/10.1111/nyas.14349
https://doi.org/10.1111/nyas.14349
Autor:
Herbert H. Seltzman, Jeffrey R. Deschamps, P. Anantha Reddy, S. Wayne Mascarella, Anita H. Lewin, Larry Brieaddy, F. Ivy Carroll, Scott E. Fix, Charles J. McElhinny, Gregory H. Imler
Publikováno v:
Bioorg Chem
Inconsistent results have been reported for the effects of the mitogen-activating extracellular kinase (MEK) inhibitor α-[amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile (SL 327) on ethanol-induced conditioned place prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a55f21d11bcceab0ad9b7d46b9c0e8
https://europepmc.org/articles/PMC8217309/
https://europepmc.org/articles/PMC8217309/
Autor:
Jeffrey R. Deschamps, Gregory H. Imler, F. Ivy Carroll, Larry Brieaddy, S. Wayne Mascarella, P. Anantha Reddy, Anita H. Lewin
Publikováno v:
ACS Chemical Neuroscience. 10:246-251
The demonstrated role of PKCβ in mediating amphetamine-stimulated dopamine efflux, which regulates amphetamine-induced dopamine transporter trafficking and activity, has promoted the research use of the selective, reversible PKCβ inhibitor (9 S)-9-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75d406708f72cbb80407e81ea2bc150b
https://doi.org/10.1021/acschemneuro.8b00196
https://doi.org/10.1021/acschemneuro.8b00196
Autor:
Ann M. Decker, S. Wayne Mascarella, Chad M. Kormos, Timothy R. Fennell, James B. Thomas, Scott P. Runyon, Rodney W. Snyder, Hernán A. Navarro, F. Ivy Carroll, Pauline W. Ondachi
Publikováno v:
Journal of Medicinal Chemistry. 61:7546-7559
Animal pharmacological studies suggest that potent and selective κ opioid receptor antagonists have potential as pharmacotherapies targeting depression, anxiety, and substance abuse (opiates, alcohol, nicotine, cocaine). We recently reported lead co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fa2f6a33a02710ba7bb081d0dfb375
https://doi.org/10.1021/acs.jmedchem.8b00674
https://doi.org/10.1021/acs.jmedchem.8b00674
Autor:
Jeffrey R. Deschamps, Moses G. Gichinga, Chad M. Kormos, S. Wayne Mascarella, F. Ivy Carroll, Gregory H. Imler, Scott P. Runyon, Hernán A. Navarro
Publikováno v:
The Journal of Organic Chemistry. 81:10383-10391
In order to gain additional information concerning the active conformation of the N-substituted trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine (1) class of opioid receptor antagonists, procedures were developed for the synthesis of structurally rig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f667197b3e06ad9819246461b3566c
https://doi.org/10.1021/acs.joc.6b01366
https://doi.org/10.1021/acs.joc.6b01366
Autor:
Pauline W. Ondachi, Hernán A. Navarro, Charles W. Luetje, Michael J. Marks, F. Ivy Carroll, Charles R. Wageman, Ana H. Castro, S. Wayne Mascarella, M. Imad Damaj
Publikováno v:
ACS Chemical Neuroscience. 7:1004-1012
In this study, we report the synthesis, nAChR in vitro and in vivo pharmacological properties of 2'-fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues (5, 6a,b, and 7a,b), which are analogues of our lead structure epibatidine. All of the analo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe43f8609503049b3b626729bfffc35
https://doi.org/10.1021/acschemneuro.6b00107
https://doi.org/10.1021/acschemneuro.6b00107
Autor:
Anita H, Lewin, Larry, Brieaddy, Jeffrey R, Deschamps, Gregory H, Imler, S Wayne, Mascarella, P Anantha, Reddy, F Ivy, Carroll
Publikováno v:
ACS chemical neuroscience. 10(1)
The demonstrated role of PKC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9cb512ea4d33b9f5c3e91a9ffc71f34
https://pubmed.ncbi.nlm.nih.gov/30156829
https://pubmed.ncbi.nlm.nih.gov/30156829
Autor:
Timothy R. Fennell, F. Ivy Carroll, Pauline W. Ondachi, James B. Thomas, Ann M. Decker, S. Wayne Mascarella, Hernán A. Navarro, Rodney W. Snyder, Scott P. Runyon, Chad M. Kormos
Publikováno v:
Journal of medicinal chemistry. 61(17)
Past studies have shown that it has been difficult to discover and develop potent and selective κ opioid receptor antagonists, particularly compounds having potential for clinical development. In this study, we present a structure—activity relatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14904304664351a106e260b89070526f
https://pubmed.ncbi.nlm.nih.gov/30117738
https://pubmed.ncbi.nlm.nih.gov/30117738
Autor:
Zhuo Ye, Charles W. Luetje, Pauline W. Ondachi, M. Imad Damaj, F. Ivy Carroll, Hernán A. Navarro, Ana H. Castro, S. Wayne Mascarella
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:5693-5701
Over the last several years we have synthesized and studied the in vitro and in vivo nAChR pharmacological properties of epibatidine (4) analogs. In this study we report the synthesis, nAChR in vitro and in vivo pharmacological properties of 3'-(subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e0ec66ddb6f75345537a75415ab0c4
https://doi.org/10.1016/j.bmc.2015.07.021
https://doi.org/10.1016/j.bmc.2015.07.021