Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S. W. Sherwood"'
Publikováno v:
Journal of Biological Chemistry. 268:23072-23080
We have shown previously that there are significant differences between mammalian cell lines in response to disruption of the assembly of the mitotic spindle apparatus (Kung, A. L., Sherwood, S. W., and Schimke, R. T. (1990) Proc. Natl. Acad. Sci. U.
Publikováno v:
British Journal of Cancer
In this study we have investigated the interaction of caffeine, a prototypic methylxanthine, and TNF on the induction of cell death in mouse and human cell lines during progression from G1 to successive phases of the cell cycle. Exposure of cells to
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Mechanisms of immunosuppressive action of mycophenolic acid (MPA) on rat lymphocytes and correlations among MPA plasma concentrations (pharmacokinetics) and its suppression of immune functions (pharmacodynamics) were studied in vitro and in vivo. In
Publikováno v:
Investigative ophthalmologyvisual science. 40(1)
To investigate the relation of senescence-related beta-galactosidase activity and telomere shortening to replicative senescence in cultured human retinal pigment epithelial (RPE) cells.A human RPE cell line was serially passaged until 80% of cells we
Autor:
C B, Harley, S W, Sherwood
Publikováno v:
Cancer surveys. 29
Telomere dynamics and changes in telomerase activity are consistent elements of cellular alterations associated with changes in proliferative state. In particular, the highly specific correlations and early causal relationships between telomere loss
Autor:
S W, Sherwood, R T, Schimke
Publikováno v:
Methods in cell biology. 46
Publikováno v:
Cancer research. 54(19)
Chinese hamster ovary (and many rodent cell lines) transiently delay mitosis and progress into a second cell cycle without undergoing cytokinesis when treated with Colcemid, whereas HeLaS3 (and most human cell lines) arrest permanently in mitosis. We
Publikováno v:
The Journal of biological chemistry. 268(31)
We have shown previously that there are significant differences between mammalian cell lines in response to disruption of the assembly of the mitotic spindle apparatus (Kung, A. L., Sherwood, S. W., and Schimke, R. T. (1990) Proc. Natl. Acad. Sci. U.
Publikováno v:
Cancer research. 50(22)
Although agents which act in a cell cycle phase specific manner are commonly used in the clinic and in basic research, it is as yet unclear why these agents are cytotoxic. In this paper, we examine the cellular events associated with the cytotoxicity
Publikováno v:
Cancer research. 50(16)
We have studied antifolate-resistant rodent cell lines with respect to dihydrofolate reductase gene expression and expression of the "classic" multidrug resistance phenotype by flow cytometry. Using a series of antifolate-resistant and colchicine-res