Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. W. Needleman"'
Publikováno v:
Oncogene. 6(9)
Acidic fibroblast growth factor (aFGF), also known as heparin-binding growth factor 1, is a mitogen for a variety of mesoderm- and neuroectoderm-derived cells. Several different aFGF mRNA species resulting from alternative splicing have been reported
Publikováno v:
BioTechniques. 9(2)
Few studies have focused on the significance of ras protein levels in human malignancy, in part because of the inherent difficulty in quantitation of the ras gene product. We have developed a method for the enzymatic determination of the ras gene pro
Autor:
S J, Meltzer, S M, Mane, P K, Wood, J H, Resau, C, Newkirk, J A, Terzakis, B I, Korelitz, W M, Weinstein, S W, Needleman
Publikováno v:
Cancer research. 50(12)
Activation of c-Ki-ras by point mutation within exon 1 was studied in 33 specimens of dysplastic gastrointestinal lesions or of cancers presumed to arise from dysplasia. Samples were obtained from patients with underlying ulcerative colitis or Barret
Publikováno v:
BioTechniques. 8(2)
An improvement over current protocols for sequencing products of the polymerase chain reaction is described. This method allows sequencing products of the reaction without performing costly, time-consuming purification steps which often result in una
Publikováno v:
Hematologic pathology. 4(3)
A case of hypereosinophilic syndrome is presented in which the patient was serially observed for 4 years. Transformation to a disorder resembling chronic myeloid leukemic (CML) occurred 36 months after diagnosis; at 42 months, blastic transformation
Publikováno v:
Postgraduate Medical Journal. 59:508-511
Summary The prompt and accurate recognition of non-malignant complications is of critical importance in the care of cancer patients. Pulmonary thromboembolism is particularly important because it is common, treatable and frequently difficult to diagn
Publikováno v:
Leukemia. 2(2)
Activation of the cellular oncogene c-N-ras has been frequently observed in DNA from leukemic cells in acute myeloid leukemia (AML). Ras gene activation sufficient to mediate in vitro transformation and rodent tumorigenesis usually results from point
Publikováno v:
Cancer. 48(6)
There have been few reports of acute leukemia presenting with a hypocellular bone marrow. All patients diagnosed as having acute leukemia were identified during a recent six-year interval who had blast cells plus promyelocytes of greater than 30% and
Publikováno v:
Leukemia. 3(11)
The proto-oncogene c-N-ras frequently bears point mutations in ANLL cell DNA which endow it with the capacity to transform NIH/3T3 cells in vitro. Chronic myelogenous leukemia (CML) is a neoplasm highly related to ANLL since it involves the same hema
Publikováno v:
Cancer treatment reports. 65(7-8)
Twenty patients are described who received chemotherapy for the diagnosis of acute myeloid leukemia but who were subsequently reclassified as having dysmyelopoietic syndrome using the French-American-British criteria. Thirteen patients had refractory