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pro vyhledávání: '"S. W. Johnny Lau"'
Medication therapy in older adults is complicated by the frequent presence of comorbidity that requires coadministration of multiple therapeutic agents. This need for polypharmacy increases the likelihood of potentially harmful drug interactions and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3c735b5c145a49c3a1a2235b2d0c44
https://doi.org/10.1016/b978-0-12-819869-8.00006-9
https://doi.org/10.1016/b978-0-12-819869-8.00006-9
Autor:
S W Johnny, Lau, Yue, Huang, Julie, Hsieh, Shenggang, Wang, Qi, Liu, Patricia W, Slattum, Janice B, Schwartz, Shiew-Mei, Huang, Robert, Temple
Publikováno v:
JAMA Network Open. 5:e2236149
ImportanceOlder age may be accompanied by changes in the pharmacokinetics or pharmacodynamics or both of medications that can result in altered safety and efficacy profiles.ObjectiveTo assess representation of older adults in clinical trials of new d
Autor:
S. W. Johnny Lau, Raman K. Baweja
Publikováno v:
Developing Drug Products in an Aging Society ISBN: 9783319430973
A few decades ago a term was coined for pediatric drug development, or lack thereof, calling children “therapeutic orphans.” Since then, tremendous strides have been made in developing drugs to benefit children. We are in a similar conundrum now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cddbab9dbe12a5f45b139b373418421
https://doi.org/10.1007/978-3-319-43099-7_35
https://doi.org/10.1007/978-3-319-43099-7_35
Autor:
Kofi Kumi, Veneeta Tandon, Seongeun Cho, Darrell R. Abernethy, S. W. Johnny Lau, Elimika Pfuma
Publikováno v:
Archives of Internal Medicine. 171
The older population is currently the fastest growing age group in the United States, and this trend is expected to continue for several decades. Older individuals, in general, have a higher disease burden compared with younger adults and are the maj