Zobrazeno 1 - 3
of 3
pro vyhledávání: '"S. W. Entwisle"'
Autor:
C. Martinez Calejman, S. Trefely, S. W. Entwisle, A. Luciano, S. M. Jung, W. Hsiao, A. Torres, C. M. Hung, H. Li, N. W. Snyder, J. Villén, K. E. Wellen, D. A. Guertin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
mTORC2 activates Akt, a regulator of cell growth and metabolism, however, the role of mTORC2 in adipocytes is incompletely understood. Here the authors report that a mTORC2-Akt axis specifically activates ACLY to promote lipid synthesis and histone a
Externí odkaz:
https://doaj.org/article/81b2d4b49afe452392aeab8cf473f847
Autor:
C. Martinez Calejman, S. Trefely, S. W. Entwisle, A. Luciano, S. M. Jung, W. Hsiao, A. Torres, C. M. Hung, H. Li, N. W. Snyder, J. Villén, K. E. Wellen, D. A. Guertin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d6c4cabd371847be97bd9a2a413bc3bf
Autor:
C, Martinez Calejman, S, Trefely, S W, Entwisle, A, Luciano, S M, Jung, W, Hsiao, A, Torres, C M, Hung, H, Li, N W, Snyder, J, Villén, K E, Wellen, D A, Guertin
Publikováno v:
Nature communications. 11(1)
mTORC2 phosphorylates AKT in a hydrophobic motif site that is a biomarker of insulin sensitivity. In brown adipocytes, mTORC2 regulates glucose and lipid metabolism, however the mechanism has been unclear because downstream AKT signaling appears unaf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ea809ab564bdb1725a76ad54cde025a4
https://pubmed.ncbi.nlm.nih.gov/32901020
https://pubmed.ncbi.nlm.nih.gov/32901020