Zobrazeno 1 - 10
of 46
pro vyhledávání: '"S. W. De Laat"'
Publikováno v:
Development. 121:1911-1925
There is evidence suggesting that pHi elevation can induce differentiation to cement gland, an extremely anterior structure, during the early development of Xenopus laevis (Picard, J. J. (1975) J. Embryol. exp. Morphol. 33, 957–967; Sive, H. L., Ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a733088fb9fe29b1ccd43a959ac3b4
https://doi.org/10.1242/dev.121.6.1911
https://doi.org/10.1242/dev.121.6.1911
Autor:
S. W. de Laat, Marcel Karperien, Clemens W.G.M. Löwik, L. H. K. Defize, Gino V. Segre, A van de Stolpe, Harald Jüppner, Abdul B. Abou-Samra
Publikováno v:
The Journal of Cell Biology
Parathyroid hormone related peptide (PTHrP), first identified in tumors from patients with the syndrome of "Humoral Hypercalcemia of Malignancy," can replace parathyroid hormone (PTH) in activating the PTH-receptor in responsive cells. Although PTHrP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ef145afa28a86c4e09b18f8889d81c
https://doi.org/10.1083/jcb.120.1.235
https://doi.org/10.1083/jcb.120.1.235
Publikováno v:
Ciba Foundation Symposium 122-Calcium and the Cell
The proliferation of cells in vivo and in culture is regulated by polypeptide growth factors, such as epidermal growth factor (EGF) and platelet-derived growth factor (PDGF). Binding of growth factors to their specific cell-surface receptors initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77dbabb8697ba34bffebb60591f4242a
https://doi.org/10.1002/9780470513347.ch13
https://doi.org/10.1002/9780470513347.ch13
Autor:
S W, de Laat, J, Boonstra, L H, Defize, W, Kruijer, P T, van der Saag, L G, Tertoolen, E J, van Zoelen, J, den Hertog
Publikováno v:
The International journal of developmental biology. 43(7)
Signalling between cells in the developing vertebrate embryo is essential for normal embryonic development. In the mid 1970's, signal transduction research started at the Hubrecht Laboratory with special emphasis on analysis of the signalling mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::956695f3f9682954dddc7949920d86c7
https://pubmed.ncbi.nlm.nih.gov/10668978
https://pubmed.ncbi.nlm.nih.gov/10668978
Autor:
L. H. K. Defize, S. W. De Laat, Marcel Karperien, H. Farih-Sips, Clemens W.G.M. Löwik, Johannes Boonstra
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 11(10)
Differentiation of P19 embryonal carcinoma (EC) and embryonal stem (ES)-5 cells with retinoic acid (RA) induces expression of PTH-related peptide (PTHrP) mRNA. In this study we have characterized a region between nucleotide (nt) −88 and −58 relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ac478baa9d5d712263504442e99049
https://pubmed.ncbi.nlm.nih.gov/9280059
https://pubmed.ncbi.nlm.nih.gov/9280059
Autor:
A, Schootemeijer, G, van Willigen, H, van der Vuurst, L G, Tertoolen, S W, De Laat, J W, Akkerman
Publikováno v:
Thrombosis and haemostasis. 77(1)
The migration of integrins to sites of cell-cell and cell-matrix contact is thought to be important for adhesion strengthening. We studied the lateral diffusion of integrin alpha IIb beta 3 (glycoprotein IIb/IIIa) in the plasma membrane of a cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf1cf0af6626d5a04f1faafe2619c40f
https://pubmed.ncbi.nlm.nih.gov/9031465
https://pubmed.ncbi.nlm.nih.gov/9031465
Activin and basic fibroblast growth factor regulate neurogenesis of murine embryonal carcinoma cells
Autor:
R F, Ameerun, J P, de Winter, A J, van den Eijnden-van Raaij, J, den Hertog, S W, de Laat, L G, Tertoolen
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(12)
Murine P19 embryonal carcinoma (EC) cells can be differentiated into various germ layer derivatives. The addition of retinoic acid (RA) to P19-EC cell aggregates results in a transient activation of receptor protein tyrosine phosphatase-alpha (RPTP a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91d711e5db634ab3b9fa696bc0effe36
https://pubmed.ncbi.nlm.nih.gov/8959336
https://pubmed.ncbi.nlm.nih.gov/8959336
Publikováno v:
The International journal of developmental biology. 40(3)
In this study we describe the spatio-temporal expression of Parathyroid Hormone related Peptide (PTHrP) mRNA during murine postimplantation development from day 5.5 post coitum (pc) until day 12.5 pc. From day 5.5 pc and onwards PTHrP mRNA was detect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8efc48b60247d0cd009df86cfc65bb6f
https://pubmed.ncbi.nlm.nih.gov/8840192
https://pubmed.ncbi.nlm.nih.gov/8840192
Publikováno v:
Advances in space biology and medicine. 4
EGF and related polypeptides are involved in the regulation of cell growth and differentiation of continuously regenerating tissues, in tissue repair processes and in placental and fetal development. Their initial mode of action generally constitutes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e70660468aeedcc8963c0eb87dd6c2db
https://pubmed.ncbi.nlm.nih.gov/7757250
https://pubmed.ncbi.nlm.nih.gov/7757250
Publikováno v:
ASGSB bulletin : publication of the American Society for Gravitational and Space Biology. 5(2)
Epidermal growth factor (EGF) activates a well-characterized signal transduction cascade in human A431 epidermal carcinoma cells. Among the early responses evoked by EGF are receptor clustering, cell rounding, and early gene expression. These process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2d1a3ba2f06a0f76a0dcfd9b267cebb
https://pubmed.ncbi.nlm.nih.gov/11537644
https://pubmed.ncbi.nlm.nih.gov/11537644